蔡三军 - 复旦大学 - 肿瘤研究所

个人简介

复旦大学附属肿瘤医院大肠癌多学科协作组首席专家、复旦大学大肠癌诊治中心主任、上海市抗癌协会大肠癌专业委员会主任委员、上海市疾病控制中心大肠癌专委会主委、CSCO肿瘤营养专委会主委、CSCO大肠癌专委会副主委、中国医师协会MDT专委会副主委、美国临床肿瘤指南(NCCN)中国版专家委员会委员、NCCN大肠癌临床实践指南（中国版）外科执笔人、主要从事结直肠癌基础和临床研究，尤其擅长于大肠癌的手术治疗，是中国著名的大肠癌专家。主编《结直肠肛门肿瘤》（北京大学出版社，2005）及《循证结直肠肛管肿瘤学》（上海科学技术出版社2015）。主持国家自然科学基金课题、国家863及973、复旦211等重大科研课题，累计经费4200余万。近5年发表医学论文90余篇，其中SCI 70余篇。2012获得上海市科学技术及教育部科技进步二等奖，2018获上海预防医学会科学技术二等奖，2019获第三届国之名医盛典-卓越建树奖和科教资讯一等奖。

研究领域

大肠癌、胃癌、软组织腹膜后肿瘤、恶性黑色素瘤等腹部肿瘤的手术治疗局部晚期大肠癌及复发转移性大肠癌的综合治疗大肠癌的早期筛查、分子生物标志物及复发转移机制研究大肠癌类器官平台建设与转化治疗

近期论文

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Chen G#, Peng J#, Xiao Q#, Wu HX#, Wu X, Wang F, Li L, Ding P, Zhao Q, Li Y, Wang D, Shao Y, Bao H, Pang Z, Ding KF*, Cai S*, Wang F*, Xu RH*. Postoperative circulating tumor DNA as markers of recurrence risk in stages II to III colorectal cancer. J Hemoatol Oncol, 2021; 14(1): 80. Hu X#, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ*. Adjuvant Chemotherapy Seemed Not to Have Survival Benefit in Rectal Cancer Patients with ypTis-2N0 After Preoperative Radiotherapy and Surgery from a Population-Based Propensity Score Analysis. Oncologist, 2019; 24(6):803-811. Zhang S#, Yang Y, Weng W, Guo B, Cai G, Ma Y, Cai S*. Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal cancer. J Exp Clin Cancer Res, 2019; 38(1):14. Hu X#, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ*. Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway. J Exp Clin Cancer Res, 2018; 37(1):41. Hu X#, Li YQ, Li QG, Ma YL, Peng JJ*, Cai SJ*. ITGAE Defines CD8+ Tumor-Infiltrating Lymphocytes Predicting a better Prognostic Survival in Colorectal Cancer. EBioMedicine, 2018; 35:178-188. Hu X#, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ*. Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer. EBioMedicine, 2018; 34:35-45. Li Q#, Dai W#, Jia H#, Li Y, Xu Y, Li X*, Cai G*, Cai S*. Prognostic Impact of Hypochloremia in Patients With Stage I to III Colorectal Cancer After Radical Resection. Dis Colon Rectum, 2018; 61(11):1273-1280. Yang Y#, Weng W#, Peng J#, Hong L#, Yang L, Toiyama Y, Gao R, Liu M, Yin M, Pan C, Li H, Guo B, Zhu Q, Wei Q, Moyer MP, Wang P, Cai S*, Goel A*, Qin H*, Ma Y*. Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-kappaB, and Up-regulating Expression of MicroRNA-21. Gastroenterology, 2017; 152(4):851-866. Li Y#, Liang L#, Dai W, Cai G, Xu Y, Li X, Li Q*, Cai S*. Prognostic impact of programed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor infiltrating lymphocytes in colorectal cancer. Mol Cancer, 2016; 15(1):55. Li Y#, Jia H#, Yu W, Xu Y, Li X, Li Q*, Cai S*. Nomograms for predicting prognostic value of inflammatory biomarkers in colorectal cancer patients after radical resection. Int J Cancer, 2016; 139(1):220-31.