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个人简介

1999年9月-2003年7月:山东师范大学化学化工与材料科学学院,理学学士;2003年9月-2009年2月:中国科学院上海有机化学研究所,理学博士,导师:胡金波研究员;2009年4月-2012年2月:美国南加州大学化学系Loker碳氢化学研究所George A. Olah教授和G. K. Surya Prakash教授联合研究组,博士后研究助理; 2012年2月-今:中国科学院上海有机化学研究所有机氟化学重点实验室,副研究员(胡金波课题组) 获奖及荣誉: 2009年:上海市优秀毕业生 2008年:中科院朱李月华优秀博士生奖学金

研究领域

基于主族元素配体偶联机理的新型氟化学反应研究 基于过渡金属参与机理的新型氟化学反应研究 具有应用目标导向的新型氟化和氟烷基化技术的开发

近期论文

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Zhang, Wei; Ni, Chuanfa; Hu, Jinbo*, “Selective Fluoroalkylation of Organic Compounds by Tackling the ‘Negative Fluorine Effect’ ”, Topics in Current Chemistry , 2012, 308, 25–44. Prakash, G. K. Surya*; Wang, Fang; Rahm, Martin; Shen, Jingguo; Ni, Chuanfa; Haiges, Ralf; Olah, George A.*, “On the Nature of C-H...F-C Interactions in Hindered CF3-C(sp3) Bond Rotations”, Angew. Chem. Int. Ed. 2011, 50, 11761–11764. Prakash, G. K. Surya*; Wang, Fang; Ni, Chuanfa; Shen, Jingguo; Haiges, Ralf; Yudin, Andrei K.; Mathew, Thomas; Olah, George A.*, “Conformational Study of 9-Dehydro-9-Trifluoromethyl Cinchona Alkaloids via 19F NMR Spectroscopy: Emergence of Trifluoromethyl Moiety as a Conformational Stabilizer and a Probe”, J. Am. Chem. Soc. 2011, 133, 9992 –9995. Prakash, G. K. Surya*; Ni, Chuanfa; Wang, Fang; Hu, Jinbo; Olah, George A.*, “From Difluoromethyl 2-Pyridyl Sulfone to Difluorinated Sulfonates: A Unique Protocol for Nucleophilic Difluoro(sulfonato)methylation”, Angew. Chem. Int. Ed. 2011, 50, 2559–2563. (Highlighted by Synfacts) Ni, Chuanfa; Hu, Jinbo*, “Selective Nucleophilic Fluoroalkylations Facilitated by Removable Activation Groups”, Synlett, 2011, 770-782. (An Invited Account) Prakash, G. K. Surya*; Wang, Fang; Ni, Chuanfa; Thomas, Tito Joe; Olah, George A.*, “Efficient Synthesis of α-(Fluoro/chloro/methoxy)disulfonylmethane Derivatives as Tunable Substituted Methyl Synthons via a New C-S Bond Forming Strategy”, J. Fluorine Chem. 2010, 131, 1007–1012. Ni, Chuanfa; Zhang Laijun; Hu, Jinbo*, “Synthesis of Fluorinated β-Ketosulfones and gem-Disulfones by Nucleophilic Fluoroalkylation of Esters and Sufinates with Di- and Monofluoromethyl Sulfones”, J. Org. Chem. 2009, 74, 3767–3771. Ni, Chuanfa; Hu, Jinbo*, “Palladium/acetic acid-catalyzed fluoroalkylation of alkynes with monofluorinated sulfones as pronucleophiles”, Tetrahedron Lett. 2009, 50, 7252–7255. Ni, Chuanfa; Zhang Laijun; Hu, Jinbo*, “Nucleophilic Fluoroalkylation of α,β-Enones, Arynes and Activated Alkynes with Fluorinated Sulfones: Probing the Hard/Soft Nature of Fluorinated Carbanions”, J. Org. Chem. 2008, 73, 5699–5713. Ni, Chuanfa; Wang Fang; Hu, Jinbo*, “Enantioselective nucleophilic difluoromethylation of aromatic aldehydes With Me3SiCF2SO2Ph and PhSO2CF2H reagents catalysed by chiral quaternary ammonium salts”, Beilstein J. Org. Chem. 2008, 4, No. 21. Ni, Chuanfa; Liu, Jun; Zhang, Laijun; Hu, Jinbo*, “A Remarkably Efficient Fluoroalkylation of Cyclic Sulfates and Sulfamidates with PhSO2CF2H: Facile Entry into β-Difluoromethylated or β-Difluoromethylenated Alcohols and Amines”, Angew. Chem., Int. Ed. 2007, 46, 786–789. Ni, Chuanfa; Li, Ya; Hu, Jinbo*, “Nucleophilic Fluoroalkylation of Epoxides with Fluorinated Sulfones”, J. Org. Chem. 2006, 71, 6829–6833. Li, Ya; Ni, Chuanfa; Liu, Jun; Zhang, Laijun; Zheng, Ji; Zhu, Lingui; Hu, Jinbo*, “Stereoselective Nucleophilic Monofluoromethylation of N-(tert-Butanesulfinyl)imines with Fluoromethyl Phenyl Sulfone”, Org. Lett. 2006, 8, 1693–1696. Ni, Chuanfa; Hu, Jinbo*, “Nucleophilic difluoromethylation of carbonyl compounds using TMSCF2SO2Ph and Mg0-mediated desulfonylation”, Tetrahedron Lett. 2005, 46, 8273–8277.

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