潘翠萍 - 复旦大学 - 粤港澳大湾区精准医学研究院（广州）

个人简介

课题组长潘翠萍，2008年博士毕业于德国马普生物化学研究所，2013年在美国斯坦福大学遗传系完成博士后培训，随后留校工作。2014年加入美国VA医疗卫生系统任职生物信息学主任，于2021年全职加入粤港澳大湾区精准医学研究院（广州）并担任青年研究员，组建生医智算（Intelligent Computing in Biomedicine）实验室。课题组长在多组学、计算生物学、生物信息学、人群队列大数据、云计算等研究方面积累了丰富的经验，在Cell, JAMA, Circulation, Plos Computational Biology等杂志发表论文23篇。

研究领域

课题组致力于用多组学技术、生物医学大数据、数据科学及数据工程等方法来统筹和融合多维度生物医学数据，以解析人类常见复杂疾病的发生发展机制，并发展人类复杂疾病的精准预测预防方法和个体化药物治疗方案。课题组长期与斯坦福大学心血管研究中心、国内几家知名医院合作，目前的研究重心为心血管代谢疾病、免疫疾病和癌症

近期论文

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Gao H*, Liu S*, Mai Y, Wang Y, Zhang X, Zheng S, Luo C#, Pan C#. Combined Therapy of Prednisone and mTOR Inhibitor Sirolimus for Treating Retroperitoneal Fibrosis. Ann Rheum Dis. 2023 Feb; doi:10.1136/ard-2022-223736 Li J*, Pan C*, Zhang S*, Spin JM, Deng A, Leung LLK, Dalman RL, Tsao PS, Snyder M. Decoding the Genomics of Abdominal Aortic Aneurysm. Cell. 2018 Sep 174 (6): 1361-1372. Dewey FE*, Grove ME*, Pan C*, Goldstein BA, Bernstein J, Chaib H, Goldfeder RL, Ormond KE, Caleshu C, Kingham K, Klein TE, Whirl-Carillo M, Sakamoto K, Wheeler MT, Butte AJ, Merker JD, Ford J, Boxer L, Loannidis JPA, Yeung AC, Altman RA, Assimes TL, Snyder M# , Ashley EA# , Quertermous T# . Clinical Interpretation and Implications of Whole Genome Sequencing. JAMA. 2014;311(10):1035-1045. Bahmani A*, Ferriter K*, Krishnan V, Alavi A, Alavi A, Tsao PS, Snyder MP# , Pan C#. Swarm: A Federated Cloud Framework for Large-Scale Variant Analysis. PLoS Comput Biol. 2021 May 12;17(5):e1008977. Bahmani A*, Xing Z*, Krishnan V*, Ray U*, Mueller F, Alavi AA, Tsao PS, Snyder MP# , Pan C#. Hummingbird: Efficient Performance Prediction for Executing Genomic Applications in the Cloud. Bioinformatics. 2021 Mar 8:btab161. Ross PB, Song J, Tsao PS#, Pan C#. Trellis for efficient data and task management in the VA Million Veteran Program. Sci Rep. 2021 Dec 1;11(1):23229. Pan C*#, McInnes G*, Deflaux N*, Snyder M, Bingham J, Datta S, Tsao PS#. Cloud-based Interactive Analytics for Terabytes of Genomic Variants Data. Bioinformatics. 2017 Dec 1;33(23):3709-3715. Pan C*, Kumar C*, Bohl S, Klingmü U, and Mann M. Comparative Proteomic Phenotyping of Cell lines and Primary Cells to Assess Preservation of Cell Type Specific Functions. Mol Cell Proteomics. Mar 01, 2009; 8: 443-450. Pan C, Olsen JV, Daub H, and Mann M. Global Effects of Kinase Inhibitors on Signaling Networks Revealed by Quantitative Phosphoproteomics. Mol Cell Proteomics. 2009 Dec;8(12):2796-808. Pan C, Gnad F, Olsen JV, and Mann M. Quantitative Phosphoproteome Analysis of a Liver Cell Line Reveals Specificity of Phosphatase Inhibitors. Proteomics. 2008 Nov;8(21):4534-46.