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Spatial transcriptomics reveals a low extent of transcriptionally active hepatitis B virus integration in patients with HBsAg loss. Xiaoqi Yu, Qiming Gong, Demin Yu, Yongyan Chen, Ying Jing*, Fabien Zoulim*, Xinxin Zhang*. Gut. 2023 Nov 15:gutjnl-2023-330577.
Divergent tumor and immune cell reprogramming underlying immunotherapy response and immune-related adverse events in lung squamous cell carcinoma. Minjiang Chen#, Pengfei Ma#, Yongchang Zhang#, Dong Wang#, Zhuang Yu, Yujie Fu , Xiaojing Zhao, Mengzhao Wang*, Guanglei Zhuang*, Ying Jing*. J Immunother Cancer. 2023 Oct;11(10):e007305.
Single-Nucleus Transcriptome Profiling of Locally Advanced Cervical Squamous Cell Cancer Identifies Neural-Like Progenitor Program Associated with the Efficacy of Radiotherapy. Lei Zhang, Jun Ma, Di Zhou, Junjun Zhou, Bin Hu, Xiumei Ma, Jianming Tang*, Yongrui Bai*, Haiyan Chen*, and Ying Jing*. Advanced Science, 2023 Sep;10(25):e2300348.
Distinct T cell sub-clusters may serve as biomarkers for immune related adverse events. Ying Jing*, Jingwen Yang, Leng Han*. Cell Report Medicine, 2023 Jan 17;4(1):100902.
Advancing CAR T-cell therapy through multi-dimensional omics data. Jingwen Yang#, Yamei Chen#, Ying Jing#, Michael R. Green*, Leng Han*. Nature Review Clinical Oncology, 2023 Jan 31
Harnessing big data to characterize immune-related adverse events. Ying Jing#, Jingwen Yang#, Douglas B Johnson*, Javid J Moslehi*, Leng Han*. Nature Review Clinical Oncology, 2022 Apr;19(4):269-280;
Association of antibiotic treatment with immune-related adverse events in cancer patients receiving immunotherapy. Ying Jing#, Xue Chen#, Kunyan Li#, Yaoming Liu, Zhao Zhang, Yiqing Chen, Yuan Liu, Yushu Wang, Steven H. Lin, Lixia Diao, Jing Wang, YanYan Lou, Douglas B. Johnson, Xiang Chen*, Hong Liu*, Leng Han*. Journal for Immunotherapy of Cancer, 2022, 10(1): e003779
Expression of chimeric antigen receptor therapy targets in subpopulations detected by single-cell sequencing of normal cells may contribute to off-tumor toxicity. Ying Jing#*, Yuan Liu#, Qiang Li, Youqiong Ye, Lixia Diao, Yun Huang, Yubin Zhou, Michael R Green, Gordon B. Mills, Leng Han*. Cancer Cell, 2021 Dec 13; 39(12):1558-1559
Association between sex and immune-related adverse events during immune checkpoint inhibitor therapy. Ying Jing#, Yongchang Zhang#, Youqiong Ye, Yaoming Liu, Yanyan Lou, Steven H. Lin, Lixia Diao, Hong Liu, Gordon B. Mills*, Leng Han*. Journal of the National Cancer Institute, 2021 Mar 10; djab035
Adverse events associated with potential drugs for COVID-19: a case study from real-world data. Ying Jing*, Lixia Diao*, Leng Han*. Briefings in bioinformatics, 2021 Mar 22; 22(2):1232-1238
Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy. Ying Jing#, Jin Liu#, Youqiong Ye, Lei Pan, Hui Deng, Yushu Wang, Yang Yang, Lixia Diao, Steven H. Lin, Gordon B. Mills, Guanglei Zhuang*, Xinying Xue*, Leng Han*. Nature Communications, 2020 Oct 2; 11(1):4946
Baseline immunity and impact of chemotherapy on immune microenviroment in cervical cancer. Yi Zhang#, Minhua Yu#, Ying Jing#, Jiejun Cheng, Caiyan Zhang, Lin Cheng, Haijiao Lu, Mei-chun Cai, Jie Wu, Wenjing Wang, Weihua Lou, Lihua Qiu, Li Tan, Huaiwu Lu, Xia Yin, Guanglei Zhuang*, Wen Di*. British Journal of Cancer, 2021 Jan; 124(2):414-424
Hybrid sequencing-based personal full-length transcriptomic analysis implicates proteostatic stress in metastatic ovarian cancer. Ying Jing#, Yi Zhang#, Hui Zhu#, Ke Zhang, Mei-Chun Cai, Pengfei Ma, Peiye Shen, Zhenfeng Zhang, Minghui Shao, Jing Wang, Minhua Yu, Xia Yin, Meiying Zhang, Yuan Hu, Danni Chen, Wen Di, Xiaojie Wang*, Guanglei Zhuang*. Oncogene, 2019 April; 38(16):3047-3060
Prevalence and clonality of synchronous primary carcinomas in the bladder and prostate. Ying Jing#, Ruiyun Zhang#, Pengfei Ma, Mei-Chun Cai, Guanglei Zhuang*, Haige Chen*. Journal of Pathology, 2018 Jan; 244(1):5-10
Comprehensive genomic profiling of neuroendocrine bladder cancer pinpoints molecular origin and potential therapeutics. Peiye Shen#, Ying Jing#, Ruiyun Zhang#, Mei-chun Cai, Pengfei Ma, Haige Chen*, Guanglei Zhuang*. Oncogene, 2018 May; 37(22):3039-3044
Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors. Shengzhe Zhang#, Meiying Zhang#, Ying Jing#, Xia Yin, Pengfei Ma, Zhenfeng Zhang, Xiaojie Wang, Wen Di, Guanglei Zhuang*. Nature Communications, 2018 Jan; 9(1):215
Clonality, heterogeneity and evolution of synchronous bilateral ovarian cancer. Xia Yin#, Ying Jing#, Mei-Chun Cai#, Pengfei Ma, Yi Zhang, Cong Xu, Meiying Zhang, Wen Di*, Guanglei Zhuang*. Cancer Research, 2017 Dec 1; 77(23):6551-6561
BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by downregulating FoxM1. Zhenfeng Zhang#, Pengfei Ma#, Ying Jing#, Ying Yan, Mei-chun Cai, Meiying Zhang, Shengzhe Zhang, Huixin Peng, Zhi-liang Ji, Wen Di, Zhenyu Gu, Wei-Qiang Gao*, Guanglei Zhuang*. Theranostics, 2016; 6(2):219-30
Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex. Deshui Jia#, Rui Dong#, Ying Jing#, Dan Xu#, Qifeng Wang, Lei Chen, Qigen Li, Yuping Huang, Yuannv Zhang, Zhenfeng Zhang, Li Liu, Shan Zheng, Qiang Xia, Hongyang Wang, Kuiran Dong*, Xianghuo He*. Hepatology, 2014; 60(5): 1686-9
SERPINA5 inhibits tumor cell migration by modulating the fibronectin-integrin β1 signaling pathway in hepatocellular carcinoma. Ying Jing#, Deshui Jia#, Chun-Ming Wong, Irene Oi-Lin Ng, Zhenfeng Zhang, Li Liu, Qifeng Wang, Fangyu Zhao, Jinjun Li, Ming Yao, Xingzhong Wu*, Xianghuo He*. Molecular Oncology, 2014; 8(2):366-77