章旭耀 - 复旦大学

个人简介

教育经历 2015.9 – 2018.7 复旦大学药学院博士 2012.9 – 2015.7 郑州大学药学院硕士 2008.9 – 2012.7 郑州大学药学院本科工作经历 2020.9 – 至今复旦大学生物药物学系青年研究员 2018.7 – 2020.8 宾夕法尼亚大学肿瘤生物学博士后获奖及荣誉 2021 上海市青年科技英才“扬帆计划”入选者 2020 上海“海外高层次人才引进计划”入选者 2018 上海市普通高等学校优秀博士毕业生 2017 ESMO Immuno Oncology Congress 2017. Poster Discussion & Travel Award 2017 宝钢教育奖学金特等奖 2017 JSMO Annual Meeting. Oral Presentation & Travel Award 2016 ESMO Asia 2016 Congress. Poster Presentation & Travel Award 2016 JSMO Annual Meeting. Oral Presentation & Travel Award 2015 河南省普通高等学校优秀毕业生 2014 研究生国家奖学金

研究领域

新型免疫治疗药物研发微环境与肿瘤免疫治疗机制研究

近期论文

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Xu C, Ju D*, Zhang X*. Cell Membrane-Derived Vesicle: A Novel Vehicle for Cancer Immunotherapy. Frontiers in Immunology. 2022;13:923598. Wang R, Liu H, He P, An D, Guo X, Zhang X*, Feng M*. Inhibition of PCSK9 enhances the antitumor effect of PD-1 inhibitor in colorectal cancer by promoting the infiltration of CD8+ T cells and the exclusion of Treg cells. Frontiers in Immunology. 2022;13:947756. Xu C, Ju D*, Zhang X*.Chimeric antigen receptor T cell therapy: challenges and opportunities in lung cancer. Antibody Therapeutics. 2022;5:73-83. Feng Z, He X, Zhang X, Wu Y, Xing B, Knowles A, Shan Q, Miller S, Hojnacki T, Ma J, Katona BW, Gade TP, Schrader J, Metz DC, June CH, Hua X*. Eradication of Neuroendocrine Tumors by CDH17CAR T Cells Without Toxicity to Normal Tissue. Nature Cancer. 2022;3:581-594. Zhang X, Wang Y, Fan J, Chen W, Luan J, Mei X, Wang S, Li Y, Ye L,Li S, Tian W, Yin K*, Ju D*. Blocking CD47 efficiently potentiated therapeuticeffects of anti-angiogenic therapy in non-small cell lung cancer. Journal for ImmunoTherapy of Cancer. 2019; 7:346. Zhang X, Fan J, Ju D*. Insights into CD47/SIRPα axis-targetingtumor immunotherapy. Antibody Therapeutics. 2018; 1:37-42. Zhang X, Chen W, Fan J, Wang S, Xian Z, Luan J, Li Y, Wang Y, NanY, Luo M, Li S, Tian W, Ju D*. Disrupting CD47-SIRPα axis alone or combinedwith autophagy depletion for the therapy of glioblastoma. Carcinogenesis. 2018;39:689-699. Zhang X, Wang S, Nan Y, Fan J, Chen W, Luan J, Wang Y, Liang Y, LiS, Tian W, Ju D*. Inhibition of autophagy potentiated the anti-tumor effects ofVEGF and CD47 bispecific therapy in glioblastoma. Applied Microbiology and Biotechnology. 2018; 102:6503-6513. Zhang X, Luan J, Chen W, Fan J, Nan Y, Wang Y, Liang Y, Meng G, JuD*. Mesoporous silica nanoparticles induced hepatotoxicity via NLRP3inflammasome activation and caspase-1-dependent pyroptosis. Nanoscale. 2018;10:9141-9152. Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, Luan J, Wang Z, Song P,Chen Q, Tian W, Ju D*. Targeting CD47 and autophagy elicited enhancedanti-tumor effects in non-small cell lung cancer. Cancer Immunology Research. 2017; 5:363-375. (Spotlight Research) Zhang X, Gu Y, Chen T, Yang D, Wang X, Jiang B, Shao K, Zhao W,Wang C, Wang J, Zhang Q, Liu H*. Synthesis, in vitro and in vivo anticanceractivities of novel 4-substituted 1,2-bis(4-chlorophenyl)-pyrazolidine-3,5-dione derivatives. MedChemComm. 2015, 6:1781-1786.