个人简介
教育经历
2009.09—2015.01 复旦大学药学院药剂学专业,博士
2005.09—2009.08 复旦大学药学院药学专业,学士
工作经历
2022.01—至今 复旦大学药学院药剂学系,青年研究员
2017.01—2022.01华中科技大学生命科学与技术学院,博士后
2015.10—2016.12 国家纳米药物工程技术研究中心,研究助理
2015.02—2015.09 复旦大学药学院药剂学教研室,研究助理
获奖及荣誉
2014年首届长三角药物制剂发展论坛大会优秀论文二等奖
2013年 AAPS中国论坛(2013 AAPS@China Symposium),Podium Presentation Award
2009年复旦大学优秀毕业生
研究领域
新型口服递药系统设计和促吸收机制研究
口服制剂的制备新工艺和评价新技术研究
近期论文
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Han Luo1, Jianyong Sheng1, Linlin Shi, Xiaoyu Yang, Jitang Chen, Tianhao Peng, Qibing Zhou, Jiangling Wan*, Xiangliang Yang. Noncovalent assembly of albumin nanoparticles by hydroxyl radical: A possible mechanism of the nab technology and a one-step green method to produce protein nanocarriers. Chemical Engineering Journal,2021,404, 126362.
Linlin Shi1, Jianyong Sheng1, Guozhong Chen, Peng Zhu, Changping Shi, Bei Li, Chaiwoo Park, Jingyi Wang, Bixiang Zhang*, Zhi Liu*, Xiangliang Yang*. Combining IL-2-based immunotherapy with commensal probiotics produces enhanced antitumor immune response and tumor clearance.Journal for ImmunoTherapy of Cancer, 2020,8, e000973.
Jianyong Sheng1, Xiaoyu Yang1, Qingyao Liu1, Han Luo, Xiquan Yin, Ming Liang,Wei Liu*, Xiaoli Lan*, Jiangling Wan*, Xiangliang Yang. Coadministration with tea polyphenols enhances the neuroprotective effect of defatted walnut meal hydrolysate against scopolamine-induced learning and memory deficits in mice. Journal of Agricultural and Food Chemistry, 2020, 68, 751-758.
Linlin Shi1, Jianyong Sheng1, Mengli Wang, Han Luo, Jun Zhu, Bixiang Zhang*, Zhi Liu*, Xiangliang Yang*. Combination therapy of TGF-β blockade and commensal-derived probiotics provides enhanced antitumor immune response and tumor suppression. Theranostics, 2019, 9, 4115-4129.
Jianyong Sheng1, Xiaoyu Yang1, Jitang Chen, Tianhao Peng, Xiquan Yin, Wei Liu, Ming Liang*, Jiangling Wan*, Xiangliang Yang. Antioxidative effects and mechanism study of bioactive peptides from defatted walnut (Juglans regia L.) meal hydrolysate. Journal of Agricultural and Food Chemistry, 2019, 67, 3305-3312.
Jianyong Sheng1, Huining He1, Limei Han, Jing Qin, Sunhui Chen, Ge Ru, Ruixiang Li, Pei Yang, Jianxin Wang?, Victor C. Yang?. Enhancing insulin oral absorption by using mucoadhesive nanoparticles loaded with LMWP-linked insulin conjugates. Journal of Controlled Release, 2016,233, 181-190.
Jianyong Sheng, Limei Han, Jing Qin, Ge Ru, Ruixiang Li, Lihong Wu, Dongqi Cui, Pei Yang, Yuwei He, Jianxin Wang*. N?trimethyl chitosan chloride-coated PLGA nanoparticles overcoming multiple barriers to oral insulin absorption. ACS Applied Materials & Interfaces, 2015,7, 15430-15441.
Huining He1, Jianyong Sheng1, Allan E. David, Young Min Kwon, Jian Zhang, Yongzhuo Huang, Jianxin Wang*, Victor C. Yang*. The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption.Biomaterials,2013, 34, 7733-7743.