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个人简介

教育经历 2017.09 – 2020.08 复旦大学,病原生物学,博士 2014.09 – 2017.07 中国农业科学院,预防兽医学,硕士 2009.09 – 2014.07 西北农林科技大学,动物医学,本科 工作经历 2022.09- 现在 复旦大学药学院 青年研究员 2020.09- 2022.08 复旦大学 基础医学院 博士后 获奖及荣誉 2023年中组部青年拔尖人才 2023年上海市青年科技启明星

研究领域

新发突发传染病防治策略研究 新型佐剂的研究 高效广谱抗病毒疫苗的研究(冠状病毒/流感病毒/肠道病毒) 抗病毒多肽以及抗体类药物的研究

近期论文

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Z. Liu#*, J. Zhou#, X. Wang#, W. Xu, Z. Teng, H. Chen, M. Chen, G. Zhang, Y. Wang, J. Huang, Q. Wang, S. Jiang*, L. Lu*. A pan-sarbecovirus vaccine based on RBD of SARS-CoV-2 original strain elicits potent neutralizing antibodies against XBB in non-human primates. Proc Natl Acad Sci U S A. 14;120(11):e2221713120. (2023). Z. Liu, L. Lu, S. Jiang*. Up or down: where comes Omicron?. Cell Research 32(7):601-602 (2022). Z. Liu#, JF. Chan#, J. Zhou#, M. Wang#, Q. Wang, G. Zhang, W. Xu, KK. Chik, Y. Zhang, Y. Wang*, KY. Yuen*, L. Lu*, S. Jiang*. A Pan-sarbecovirus Vaccine Induces Highly Potent and Durable Neutralizing Antibody Responses in Non-human Primates against SARS-CoV-2 Omicron Variant. Cell Research 32(5):495-497 (2022). Z. Liu#, J.Zhou#, W. Xu#, W. Deng#, Y. Wang#, M. Wang#, Q. Wang, M. Hsieh, J. Dong, X. Wang, W. Huang, L. Xing, M. He, C. Tao, Y. Xie, Y. Zhang*, Y. Wang*, J. Zhao*, Z. Yuan*, C. Qin*, S. Jiang*, L. Lu*. A novel STING Agonist-Adjuvanted Pan-Sarbecovirus Vaccine Elicits Potent and Durable Neutralizing Antibody and T Cell Responses in Mice, Rabbits and NHPs. Cell Research. 32(3):269-287 (2022). Z. Liu#, W. Xu#, Z. Chen#, W. Fu#, W. Zhan#, Y. Gao#, J. Zhou#, Y. Zhou, J. Wu, Q. Wang, X. Zhang, A. Hao, W. Wu, Q. Zhang, Y. Li, K. Fan, R. Chen, Q. Jiang, CT. Mayer, T. Schoofs, Y. Xie, S. Jiang, Y. Wen, Z. Yuan*, K. Wang*, L. Lu*, L. Sun*, Q. Wang*. An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope. Protein Cell. 13(9):655-675 (2022). Y. Fang#, Z. Liu#, Y. Qiu#, J. Kong, Y. Fu, Y. Liu, C. Wang, J. Quan, Q. Wang, W. Xu, L. Yin, J. Cui, Y. Xu, S. Curry, S. Jiang, L. Lu*, X. Zhou*. Inhibition of viral suppressor of RNAi proteins by designer peptides protects from enteroviral infection in vivo. Immunity. 54(10):2231-2244.e6 (2021). (封面,被Faulty Opionon推荐) Z. Liu#, W. Xu#, S. Xia#, C. Gu#, X. Wang, Q. Wang, J. Zhou, Y. Wu, X. Cai, D. Qu, T. Ying, Y. Xie, L. Lu*, Z. Yuan*, S. Jiang*. RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response. Signal Transduction and Targeted Therapy. 5(1):282 (2020). J. Zhou#, W. Xu#, Z. Liu#, C. Wang#, S. Xia, Q. Lan, Y. Cai, S. Su, J. Pu, L. Xing, Y. Xie*, L. Lu*, S. Jiang*, Q. Wang*. A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases. Acta Pharmaceutica SinicaB. 12(4):1652-1661 (2022). Y. Zhou#, Z. Liu#*, S. Li#, W. Xu#, Q. Zhang, IT. Silva, C. Li, Y. Wu, Q. Jiang, Z. Liu, Q. Wang, Y .Guo, J. Wu, C. Gu, X. Cai, D. Qu, CT. Mayer, X. Wang, S. Jiang, T. Ying, Z. Yuan*, Y. Xie*, Y. Wen*, L. Lu*, Q. Wang*.Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD. Cell Reports. 34(5):108699 (2021). Z. Liu, S. Xia, X. Wang, Q. Lan, P. Li, W. Xu, Q. Wang, L. Lu*, S. Jiang*. Sodium Copper Chlorophyllin Is Highly Effective against Enterovirus (EV) A71 Infection by Blocking Its Entry into the Host Cell. ACS Infect Dis. 26(5):882-890 (2020). N. Zhang#, Q. Ji#, Z. Liu#, K. Tang, Y. Xie, K. Li, J. Zhou, S. Li, H. Shang, Z. Shi, T. Zheng, J. Yao, L. Lu*, S. Yuan*, S. Jiang*. Effect of Different Adjuvants on Immune Responses Elicited by Protein-Based Subunit Vaccines against SARS-CoV-2 and Its Delta Variant. Viruses 14(3):501 (2022). Z. Liu#, S. Xia#, X. Wang, Q. Lan, W. Xu, Q. Wang, S. Jiang*, L. Lu*. Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection. Virol Sin. 35(3):340-343 (2020). Z. Liu, J. Shao, F. Zhao, G. Zhou, S. Gao, W. Liu, J. Lv, X. Li, Y. Li, H. Chang*, Y. Zhang*. Chemiluminescence Immunoassay for the Detection of Antibodies against the 2C and 3ABC Nonstructural Proteins Induced by Infecting Pigs with Foot-and-Mouth Disease Virus. Clin Vaccine Immunol. 24(8):e00153-17 (2017).

学术兼职

中国药理学会抗炎免疫药理青年委员会常务委员 中国疫苗行业协会疫苗基础研究专业委员会 委员 Frontiers in immunology 客座编辑 Current Research in Microbial Sciences 客座编辑

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