张醉 - 复旦大学 - 基础医学院

个人简介

教育经历 2005.09—2009.09 华中科技大学生物药学专业本科生 2009.09—2012.03 华中科技大学基础医学药理专业硕士研究生 2012.10—2016.10 日本名古屋大学分子生物学专业博士研究生工作经历 2016.10—2020.05 复旦大学基础医学院博士后 2020.05—至今复旦大学基础医学院青年副研究员获得奖项 2021，优秀博士后，复旦大学 2019，百特医药青年论文奖一等奖，百特医药公司 2019，中国药剂学大会青年论文展报一等奖，中国药剂学大会

研究领域

脑部疾病领域：发病机制、药物治疗、基于体内功能化策略的脑靶向药物递送方式研究纳米制剂领域：高端纳米载体/基因疫苗的设计和体内过程研究

近期论文

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Wenjing Tang#; Zui Zhang#; Cheng Li#; Yuxiu Chu; Jun Qian; Tianlei Ying*; Weiyue Lu*; Changyou Zhan*. Facile Separation of PEGylated Liposomes Enabled by Anti-PEG scFv, Nano Letters, 2021, 21( 23): 10107-10113 Zui Zhang#; Yuxiu Chu#; Cheng Li#; Wenjing Tang; Jun Qian; Xiaoli Wei; Weiyue Lu; Tianlei Ying*; Changyou Zhan*. Anti-PEG scFv corona ameliorates accelerated blood clearance phenomenon of PE Gylated nanomedicines. J Control Release, 2020, 330: 493-501 Yuxiu Chu#; Wenjing Tang#; Zui Zhang*; Cheng Li#; Jun Qian; Xiaoli Wei; Tianlei Ying; Weiyue Lu; Changyou Zhan*; Deciphering Protein Corona by scFv-Based Affinity Chromatography. Nano Letters, 2021, 21(5): 2124-2131 Zhang, Zui#; Guan, Juan; Jiang, Zhuxuan; Yang, Yang; Liu, Jican; Hua, Wei; Mao, Ying; Li, Cheng; Lu, Weiyue; Qian, Jun; Zhan, Changyou; Brain-targeted drug delivery by manipulating prote in corona functions. Nature Communications, 2019, 10: 0-3561 Zui Zhang#; Yoshiko Takeda-Uchimura; Tahmina Foyez; Shiori Ohtake-Niimi; Narentuya NA; Hir oyasu Akatsu; Kazuchika Nishitsuji; Makoto Michikawa; Tony Wyss-Coray; Kenji Kadomatsu; Kenji Uchimura*; Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's p athology. Proceedings of the National Academy of Sciences of the United States of America, 2017 , 114(14): 2947-2954 Zui Zhang#; Shiori Ohtake-Niimi; Kenji Kadomatsu; Kenji Uchimura ; Reduced molecular size and altered disaccharide composition of cerebral chondroitin sulfate upon Alzheimer's pathogenesi s in mice., Nagoya J. Med. Sci., 2016, 78: 293-301 Huan, Wang; Zui, Zhang; Juan, Guan; Weiyue, Lu; Changyou, Zhan ; Unraveling GLUT-mediated transcytosis pathway of glycosylated nanodisks, Asian Journal of Pharmaceutical Sciences, 2020 Guan, J; Shen, Q; Zhang, Z; Jiang, Z; Yang, Y; Lou, M; Qian, J; Lu, W; Zhan, C. ; Enhance d immunocompatibility of ligand-targeted liposomes by attenuating natural IgM absorption, Nature Communications, 2018, 9(1): 0-2982 Juan Guan; Zui Zhang; Xuefeng Hu; Yang Yang; Zhilan Chai; Xiaoqin Liu; Jican Liu; Bo Gao; Weiyue Lu; Jun Qian; Changyou Zhan ; Cholera Toxin Subunit B Enabled Multifunctional Glioma-Targe ted Drug Delivery, Adv Healthc Mater, 2017, 6(23) Wu, Peng-Fei; Zhang, Zui; Guan, Xin-Lei; Li, Yuan-Long; Zeng, Jian-Hua; Zhang, Juan-Juan; Long, Li-Hong; Hu, Zhuang-Li; Wang, Fang; Chen, Jian-Guo ; A specific and rapid colorimetric meth od to monitor the activity of methionine sulfoxide reductase A., Enzyme Microb Technol, 2013, 53( 6-7): 391-397