张俊琪 - 复旦大学 - 基础医学院

个人简介

教育经历中国药科大学微生物制药本科、生物药物化学硕士复旦大学病原生物学博士工作经历复旦大学基础医学院病原生物学助教、讲师、副教授美国约翰斯.霍普金斯大学卡耐基研究所访问研究员获得奖项 2020年首届复旦大学教师教学创新比赛一等奖 2020年国家级一流本科课程（袁正宏、瞿涤、张俊琪、谢幼华、吴健） 2020年复旦大学本科教学成果特等奖：“案例驱动法在医学微生物学本科教学中的探索与创新”（袁正宏、瞿涤、张俊琪、谢幼华、吴健） 2020年上海医学院第六届PBL教案撰写大赛英文教案一等奖（吴健、张俊琪）

研究领域

肿瘤微环境响应型智能纳米载药系统的设计、制备及细胞内转运核酸类、多肽类抗病毒药物的设计、筛选与递送核酸适配体在肠道感染性疾病诊治中的应用

近期论文

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Jing Pu, Yu Dai, Qian Wang, Lu Lu, Junqi Zhang, Wei Xu, Lan Xie, Shengqi Wang, Fei Yu, Xiaoyang He, Shibo Jiang. Rational Design of A Novel Small-Molecule HIV-1 Inactivator Targeting Both gp120 and gp41 of HIV-1, Front Pharmacol. 2021 Jan 25;11:613361. Bin Lei, Miaoxin Chen, Yizhou Wang, Junqi Zhang*, Shouhong Xu*, Honglai Liu. Double Security Drug Delivery System DDS Constructed by Multi-Responsive (pH/redox/US) Colloids Surf B Biointerfaces. (2020), https://doi.org/10.1016/j.colsurfb.2020.111022. Yinxing Shen, Mengya Li, Tianqi Liu, Jing Liu, Youhua Xie, Junqi Zhang*, Shouhong Xu*, Honglai Liu. A dual-functional HER2 aptamer-conjugated, pH-activated mesoporous silica nanocarrier-based drug delivery system provides in vitro synergistic cytotoxicity in HER2-positive breast cancer cells. Int J Nanomedicine 2019:14 4029–4044 Yinxing shen†, Junqi Zhang†, Weiju Hao, Tong Wang, Jing liu, Youhua Xie, Shouhong Xu, honglai liu. Copolymer micelles function as pH-responsive nanocarriers to enhance the cytotoxicity of a HER2 aptamer in HER2-positive breast cancer cells, Int J Nanomedicine 2018, 537–553. Weiju Hao, Tong Wang, Danyang Liu, Yazhuo Shang, Junqi Zhang*, Shouhong Xu*, Honglai Liu Folate-conjugated pH-controllable fluorescent nanomicelles acting as tumor targetable drug carriers. Microchimica Acta（2017）, 2881–2891. Weiju Hao, Yinxing Shen, Danyang Liu, Yazhuo Shang, Junqi Zhang*, Shouhong Xu*, Honglai Liu. Dual-pH-sensitivity and tumour targeting core–shell particles for intracellular drug delivery. RSC Advances（2017）,851-860. Weiju Hao, Danyang Liu, Yazhuo Shang, Junqi Zhang*, Shouhong Xu*, Honglai Liu. pH-Triggered copolymer micelles as drug nanocarriers for intracellular delivery. RSC Advances（2016）, 29149–29158. Xiaoli Ye, Ming Zhou, Yonggang He, Yanmin Wan, Weiya Bai, Shuai Tao, Yanqin Ren, Xinxin Zhang, Jianqing Xu, Jing Liu, Junqi Zhang*, Kanghong Hu*, Youhua Xie*. Efficient Inhibition of Hepatitis B Virus Infection by a preS1-binding Peptide. Sci Rep.（2016）, doi: 10.1038/srep29391. Liang Yan, Su Qu, Gang Liu, Lei Liu, Yao Yu, Guohui Ding, Yanfeng Zhao, Yixue Li, Youhua Xie*, Junqi Zhang*, Di Qu*. Comparative Transcriptomic Analysis of Primary Duck Hepatocytes Provides Insight into Differential Susceptibility to DHBV Infection. PLoS One（2016）, DOI:10.1371/journal.pone.0149702. Danyang Liu, Junqi Zhang*, Shouhong Xu* and Honglai Liu. Membrane property and biofunction of phospholiposome incorporated with anomeric galactolipids，Springerplus（2016）, doi: 10.1186/s40064-016-2236-z.

学术兼职

中国微生物学协会和上海市微生物学协会终身会员，美国细胞生物学协会会员 “以学为中心的课程设计（LCCD）”高校教师在线培训项目培训师 FD-QM高等教育在线课程质量标准评审师培训师、评审师