张春翌 - 复旦大学 - 基础医学院

个人简介

教育经历 2005.9-2009.6 复旦大学，生物化学与分子生物学，博士 1999.9-2002.6 徐州医学院，生物化学与分子生物学，硕士 1994.9-1999.6 徐州医学院，临床医学，学士工作经历 2003.12-至今历任复旦大学助教、讲师及副教授 2011.12-2012.12 美国克利夫兰医学研究中心，访问学者

研究领域

聚焦肿瘤信号转导，肿瘤表观遗传学和肿瘤免疫的相关机制研究

近期论文

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Chunyi Zhang1*, Kunpeng Zhang1, Jie Gu, Di Ge*, ENO1 promotes antitumor immunity by destabilizing PD-L1 in NSCLC. Cell Mol Immunol. 2021，18(8): 2045-2047. Chunyi Zhang*, Mingming Zhang, Shushu Song, Cathepsin D enhances breast cancer invasion and metastasis through promoting hepsin ubiquitin-proteasome degradation, Cancer letters. 2018, 438: 105-115. Qian Qian Cai1, Yi Wei Dong, Rong Wang, Bing Qi, Jun Xia Guo, Jing Pan, Yuan Yuan Liu, Chun Yi Zhang*, Xing Zhong Wu*, MiR-124 inhibits the migration and invasion of human hepatocellular carcinoma cells by suppressing integrin αV expression, Sci Rep. 2017, 7:40733. Mingming Zhang, Junjie Zhao, Wenyi Tang, Yanru Wang, Peike Peng, Lili Li, Shushu Song, Hao Wu, Can Li, Caiting Yang, Xuefei Wang*, Chunyi Zhang*, Jianxin Gu. High Hepsin expression predicts poor prognosis in Gastric Cancer, Sci Rep. 2016, 6:36902. Mingming Zhang, Jianxin Gu, Chunyi Zhang*, Hepatitis B virus X protein binding to hepsin promotes C3 production by inducing IL-6 secretion from hepatocytes, Oncotarget. 2016, 7 (7):7780-800. Chunyi Zhang, Mingming Zhang, Qingyu Wu, Jianhao Peng, Yuanyuan Ruan, Jianxin Gu, Hepsin inhibits CDK11p58 IRES activity by suppressing unr expression and eIF-2α phosphorylation in prostate cancer, cellular signaling, 2015, 27(4):789-97.