个人简介
教育经历
2002.09-2005.07,南京农业大学,动物医学院,预防兽医学博士研究生
1999.09-2002.07,山东农业大学,动物科技学院,预防兽医学硕士研究生
1995.09-1999.07,山东农业大学,动物科技学院,畜牧兽医师范专业本科生
工作经历
2007.09-至今,复旦大学,基础医学院,讲师、副教授
2014.11-2015.12,美国宾夕法尼亚大学佩雷尔曼医学院微生物学系,访问学者
2005/09-2007/09,上海交通大学,生命科学院,博士后
获得奖项
2021,复旦大学五四青年奖章集体(主要负责人)
2020,复旦大学抗击新冠肺炎疫情先进个人
研究领域
冠状病毒抗宿主先天免疫调控及致病机制研究
EBV潜伏感染及致瘤机制研究
近期论文
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Yunqing Gu #, Jun Cao # , Xinyu Zhang #, Hai Gao # , Yuyan Wang #, Jia Wang # , Juan He #, Xiaoyi Jiang #, Jinlan Zhang, Guanghui Shen, Jie Yang, Xichen Zheng, Gaowei Hu, Yuanfei Zhu, Shujuan Du , Yunkai Zhu, Rong Zhang, Jianqing Xu, Fei Lan, Di Qu, Guoliang Xu, Yun Zhao*, Dong Gao*, Youhua Xie*, Min Luo* and Zhigang Lu*. Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2. Cell Res. 2022 Jan;32(1):24-37.
Yinghui Liu#, Gaowei Hu#, Yuyan Wang#, Wenlin Ren#, Xiaomin Zhao#, Fansen Ji, Yunkai Zhu, Fei Feng, Mingli Gong, Xiaohui Ju, Yuanfei Zhu, Xia Cai, Jun Lan, Jianying Guo, Min Xie, Lin Dong, Zihui Zhu, Jie Na, Jianping Wu, Xun Lan, Youhua Xie, Xinquan Wang, Zhenghong Yuan, Rong Zhang* and Qiang Ding*. Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2, Proc Natl Acad Sci USA. 2021 Mar 23; 118(12): e2025373118.
Yunkai Zhu#, Fei Feng#, Gaowei Hu#, Yuyan Wang#, Yin Yu, Yuanfei Zhu, Wei Xu, Xia Cai, Zhiping Sun, Wendong Han, Rong Ye, Hongjun Chen, Qiang Ding, Di Qu, Youhua Xie, Qiliang Cai*, Zhenghong Yuan*, Rong Zhang*. A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry, Nature Communications, 2021, 12(1): 961
张荣#,易志刚#,王玉燕#,滕峥#,徐巍,宋武慧,蔡霞,孙志平,谷陈建,周艳秋,陈洪友,叶荣,韩文东,朱云凯,冯飞,房方皓,李崇山,张曦,瞿涤,付晨*,谢幼华*,袁正宏*,新型冠状病毒上海株(nCoV-SH01)的分离和鉴定,微生物与感染,2020,15(1):111-121.
Yuyan Wang#, Shujuan Du#, Caixia Zhu#, Chong Wang#, Nuoya Yu, Ziqi Lin, Jin Gan, Yi Guo, Xinxin Huang, Yuping He, Erle Robertson, Di Qu, Fang Wei, Qiliang Cai*, STUB1 Is Targeted by the SUMO-Interacting Motif of EBNA1 to Maintain Epstein-Barr Virus Latency, PLoS Pathogens, 2020, 16(3):e1008447.
Xiaohui Mo#, Shujuan Du#, Xiaoting Chen#, Yuyan Wang#, Xiaoqing Liu#, Chongqi Zhang, Caixia Zhu, Ling Ding, Ying Li, Yin Tong, Qiang Ju, Di Qu, Fei Tan*, Fang Wei*, Qiliang Cai*. Lactate Induces Production of the tRNA(His) Half to Promote B-lymphoblastic Cell Proliferation, Molecular Therapy, 2020, 28(11): 2442-2457
Feng Gu#, Chong Wang#, Fang Wei#, Yuyan Wang#, Qing Zhu, Ling Ding, Wenjia Xu, Caixia Zhu, Cankun Cai, Zhikang Qian, Zhenghong Yuan, Erle Robertson, Qiliang Cai*, STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus. PLoS Pathogens, 2018, 14(12):e1007416.
Yize Li#, Shuvojit Banerjee#, Yuyan Wang#, Stephen A. Goldstein, Beihua Dong, Christina Gaughan, Robert H. Silverman*, and Susan R. Weiss*. Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses. PNAS, 2016, 113(8):2241-2246.