个人简介
教育经历
2008.09—2013.06 天津医科大学 本科生
2013.09—2018.06 复旦大学病理学与病理生理学 博士研究生
工作经历
2018.06—2020.09 复旦大学 博士后
2020.10—至今 复旦大学基础医学院青年副研究员
获得奖项
2021,第十六届张锡钧基金全国学术交流会优秀口头汇报奖
2020,上海市科学技术奖二等奖
2020,龚兰生青年学者
研究领域
心血管再生和心血管重构机制研究及干预、干细胞生物学及干细胞治疗心血管疾病研究
近期论文
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Wei X#, Guo J#, Li Q, Jia Q, Jing Q, Li Y, Zhou B, Chen J, Gao S, Zhang X, Jia M, Niu C, Yang W, Zhi X, Wang X, Yu D, Bai L, Wang L, Na J, Zou Y, Zhang J, Zhang S*, Meng D*. Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells. Science Advances, 2019; 5(3):eaau7887
Niu C#, Wang S#, Guo J#, Wei X#, Jia M#, Chen Z, Gong W, Qin Y, Wang X, Zhi X, Lu M, Chen S, Gu M, Zhang J, Han J, Lan F*, Meng D*. BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains Pluripotency. Nucleic Acids Research, 2021Jan 2 7;gkab034.
Jiang L#, Yin M#, Wei X#, Liu J, Wang X, Niu C, Kang X, Xu J, Zhou Z, Sun S, Wang X, Zheng XJ, Duan S, Yao K, Qian R, Sun N, Chen AF, Wang R, Zhang J, Chen S*, Meng D*.Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis. Circulation Research. 2015,117 (4):364-75
Jiang L#, Jia M#, Wei X#, Guo J, Hao S, Mei A, Zhi X, Wang X, Li Q, Jin J, Zhang J, Li S*, Meng D*.Bach1-induced suppression of angiogenesis is dependent on the BTB domain. EBioMedicine. 2020, 51:102617.
Guo J#, Wei X#, Li Q#, Li L, Yang Z, Shi Y, Qin Y, Zhang X, Wang X, Zhi X, Meng D*. Single‐cell RNA analysis on ACE2 expression provides insights into SARS‐CoV‐2 potential entry into the bloodstream and heart injury. Journal of Cellular Physiology. 2020 Dec;235(12):9884-9894.
Jin J, Wei X, Zhi X, Wang X, Meng D. Drp1-dependent mitochondrial fission in cardiovascular disease. Acta Pharmacologica Sinica 2020, 0:1–10. doi.org/10.1038/s41401-020-00518-y.
Kang X#, Wei X#, Wang X, Jiang L, Niu C, Zhang J, Chen S, Meng D*. Nox2 contributes to the arterial endothelial specification of mouse induced pluripotent stem cells by upregulating Notch signaling. Scientific Reports. 2016;6: 33737.
Kang X#, Wei X#, Jiang L, Niu C, Zhang J, Chen S*, Meng D*. Nox2 and Nox4 regulate self-renewal of murine induced-pluripotent stem cells. IUBMB Life. 2016, 68 (12):963~ 970.