王茜 - 复旦大学 - 基础医学院

个人简介

教育经历 2001.09—2005.06 苏州大学生物技术专业本科生 2006.09—2008.08 韩国庆尚大学环境生命科学专业硕士研究生 2015.09—2019.06 复旦大学病原生物学专业博士研究生工作经历 2008.09—2009.07 清华大学环境科学与工程系科研助理 2009.08—2011.06 中科院上海巴斯德研究所科研助理 2011.07—至今复旦大学基础医学院病原生物学系实验师获得奖项 2021，JB protein for cervical cancer/AIDS prevention，日内瓦发明展览会银奖 2019，双重预防艾滋病和宫颈癌的新型制剂，第二十一届中国国际高新技术成果交易会优秀产品奖

研究领域

重要病毒防治及抗病毒靶点及药物研究，包括病毒入侵环节新靶点的发现及其入侵抑制剂新药物的研发新型抗病毒药物交叉技术研究：mRNA技术+多肽设计技术

近期论文

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Wang, Qian#；Su, Shan#；Xue, Jing#；Yu, Fei；Pu, Jing；Bi, Wenwen；Xia, Shuai；Meng, Yu；Wang, Cong；Yang, Wenqian；Xu, Wei；Zhu, Yun；Zheng, Qinwen；Qin, Chuan*；Jiang, Shibo*；Lu, Lu*. An amphipathic peptide targeting the gp41 cytoplasmic tail kills HIV-1 virions and infected cells. Sci Transl Med. 2020 Jun 3;12(546):eaaz2254，2020 Zhou, Jie#; Xu, We#; Liu, Zezhong#; Wang, Chao#; Xia, Shuai; Lan, Qiaoshuai; Cai, Yanxing; Su, Shan; Pu, Jing; Xing, Lixiao; Xie, Youhua*; Lu, Lu*; Jiang, Shibo*; Wang, Qian*. A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases . Acta Pharm Sin B. 2021 Aug 2. doi: 10.1016/j.apsb.2021.07.026. Online ahead of print, 2021 Xia, Shuai#; Lan, Qiaoshuai#; Su, Shan#; Wang, Xinling#; Xu, Wei; Liu, Zezhong; Zhu, Yun; Wang, Qian*; Lu, Lu*; Jiang, Shibo*. The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin. Signal Transduct Target Ther. 5(1):92; 2020 Wang, Qian#; Dai, Yanyan#; Sun, Zhiwu; Su, Xiaojie; Yu, Yufeng; Hua, Chen; Xu, Wei; Jiang, Shibo*; Lu, Lu*. HIV-1 Env DNA prime plus gp120 and gp70-V1V2 boosts induce high level of V1V2-specific IgG and ADCC responses and low level of Env-specific IgA response: implication for improving RV144 vaccine regimen. Emerg Microbes Infect. 6(11):e102, 2017 Qi, Qianqian#; Wang, Qian#; Chen, Weizao; Du, Lanying; Dimitrov, Dimiter S.; Lu, Lu*; Jiang, Shibo*. HIV-1 gp41-targeting fusion inhibitory peptides enhance the gp120-targeting protein-mediated inactivation of HIV-1 virions. Emerg Microbes Infect. 6(6):e59, 2017