王松梅 - 复旦大学 - 基础医学院

个人简介

教育经历 1987.9-1992.6安徽医科大学卫生系本科生 1994.9-1997.6上海医科大学生物物理学专业硕士研究生 2000.9-2004.6复旦大学生物化学与分子生物学专业博士研究生工作经历 1992.7-1994.8安徽省蚌埠市职业病防治所医师 1997.7-2000.6上海医科大学生物物理学系助教 2000.6-目前复旦大学基础医学院医学实验教学中心讲师、副教授 2011.6-2012.8美国Johns Hopkins医学院访问学者获得奖项 2001.6上海市科技进步三等奖 2016.中华医学会百篇优秀论文三等奖 2013上海市教委本科重点课程 2008复旦大学研究生教学成果二等奖 2007复旦大学教学成果三等奖

研究领域

肿瘤分子生物学。血液系统恶性肿瘤的发生机制及治疗；肝癌的免疫微环境及抗粘附小分子肽的抑瘤作用病毒性腹泻研究。我国5岁以下儿童的腹泻感染谱；诺如病毒和轮状病毒的感染机制及疫苗研制；DNA疫苗研究

近期论文

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Canjing Zhang*, Huiwen Xu*, Xianxian Sui, Lina Chen, Bobin Chen, Haozhen Lv, Songmei Wang# Xuanyi Wang#. Icaritin inhibits PLK1 to activate DNA damage response in NK/T cell lymphoma and increases sensitivity to combined gemcitabine, oxaliplatin, and L-asparaginase (GELOX). Molecular Therapy–Oncolytics, 2022(on line) Hong-Lu Zhou 1,† , Li-Na Chen 1,†, Song-Mei Wang 2,†, Ming Tan 3,4 , Chao Qiu 1 , Tian-Yi Qiu 5,* and Xuan-Yi Wang. Prevalence and Evolution of Noroviruses between 1966 and 2019, Implications for Vaccine Design. Pathogens. 10:1012, 2021 Zhou HL*, Bessey T*, Wang SM*, Mo ZJ*, Barclay L, Wang JX, Zhang CJ, Ma JC, Qiu C, Zhao G, Li RC, Zhao YL, Jiang BM#, Wang XY#. Burden and Etiology of Moderate and Severe Diarrhea in Children Less than 5 Years of Age Living in North and South of China: Prospective, Population-based Surveillance. Gut Pathogens. 13-33, 2021 Jin-Xia Wang*, Li-Na Chen*, Can-Jing Zhang*, Hong-Lu Zhou, Yan-Hong Zhang, Xin-Jiang Zhang, Zhi-Yong Hao, Chao Qiu, Jing-Chen Ma, Yu-Liang Zhao, Weiming Zhong, Ming Tand, Xi Jiang, Song-Mei Wang#, Xuan-Yi Wang#. Genetic susceptibility to rotavirus infection in Chinese children: A population-based case-control study. Human Vaccines & Immunotherapeutics. 17（6）：1803-1810, 2021 Zhou HL*, Wang SM*, von Seidlein L, Wang XY. The epidemiology of norovirus gastroenteritis in China: disease burden and distribution of genotypes . Front Med. 14(1): 1-7, 2020 Wang JX, Zhou HL, Mo ZJ, Wang SM, Hao ZY, Li Y, Zhen SS, Zhang CJ, Zhang XJ, Ma JC, Qiu C, Zhao G, Jiang B, Jiang X, Li RC, Zhao YL, Wang XY. Burden of viral gastroenteritis in children living in rural China: Population-based surveillance [J]. Int J Infect Dis. 90: 151-60, 2020 Xianxian Sui*, Canjing Zhang*, Yudong Jiang, Jianan Zhou, Chen Xu, Feng Tang, Bobin Chen, Huiwen Xu, Songmei Wang#, Xuanyi Wang#. Resveratrol activates DNA damage response through inhibition of polo-like kinase 1 (PLK1) in natural killer/T cell lymphoma. Annals of Translational Medicine. 8(11):688-701, 2020 Jianan Zhou, Canjing Zhang, Xianxian Sui, Shengxuan Cao, Feng Tang, Shuhui Sun, Songmei Wang#, Bobin Chen#. Histone deacetylase inhibitor chidamide induces growth inhibition and apoptosis in NK/T lymphoma cells through ATM-Chk2-p53-p21 signalling pathway. Invest New Drugs. 36(4): 571-580, 2018 Xianxian Sui, Canjing Zhang, Jianan Zhou, Shengxuan Cao, Chen Xu, Feng Tang, Xiuling Zhi, Bobin Chen, Songmei Wang# and Lianhua Yin#. Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA damage response pathway. Journal of experimental and clinical cancer research. 36（1）:133, 2017 Ting Wu*, Songmei Wang*, Jinfeng Wu, Zhiguang Lin, Xianxian Sui, Xiaoping Xu, Norio Shimizu, Bobin Chen# and Xuanyi Wang#. Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma. Journal of Experimental and Clinical Cancer Research. 34:17-27, 2015

学术兼职

2014.10-2020.10 上海市生物物理学会理事、副秘书长 2020.10-目前上海市生物物理学会副秘书长兼日常办公室副主任 2015.-目前内科理论与实践杂志编委