个人简介
教育经历
2005.09-2009.07 扬州大学,本科
2009.09-2012.07 中国农业科学院,硕士
工作经历
2020.10-至今 复旦大学基础医学院病原诊断高通量测序中心,实验师
2014.10-2019.05 美国圣路易斯华盛顿大学医学院基因科技与生物信息合成中心,科研助理
2012.08-2012.05 德国勃林格殷格翰(亚洲)动物研发中心,项目科学家
获得奖项
2012.12 被评为德国勃林格殷格翰(亚洲)动物研发中心“最佳员工”(1/1)
研究领域
基于二代和三代高通量测序技术平台鉴别诊断临床复杂感染性样品及数据分析
近期论文
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Campbell TP, Sun X, Patel VH, Sanz C, Morgan D, Dantas D. The microbiome and resistome of chimpanzees, gorillas, and humans across host lifestyle and geography. The ISME Journal 2020; doi:10.1038/s41396-020-0634-2
Gasparrini AJ, Wang B, Sun X, Kennedy EA, Hernandez-Leyva A, Ndao IM, Tarr PI, Warner BB & Dantas G**. Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome. Nature Microbiology 2019; doi:10.1038/s41564-019-0550-2
D'Souza AW*, Moodley-Govender E*, Berla B, Kelkar T, Wang B, Sun X, Daniels B, Coutsoudis A, Trehan I, Dantas G. Cotrimoxazole prophylaxis increases resistance gene prevalence and α-diversity but decreases β-diversity in the gut microbiome of HIV-exposed, uninfected infants. Clinical Infectious Diseases 2019; doi:10.1093/cid/ciz1186
D'Souza AW*, Potter RF*, Wallace M, Shupe A, Patel S, Sun X, Gul D, Kwon JH, Andleeb S**, Burnham CD**, Dantas G**. Spatiotemporal dynamics of multidrug resistant bacteria on intensive care unit surfaces. Nature Communications 2019; doi:10.1038/s41467-019-12563-1
Crook N*, Ferreiro A*, Gasparrini AJ, Pesesky MW, Gibson MK, Wang B, Sun X, Condiotte Z, Dobrowolski S, Peterson D, Dantas G**. Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut. Cell Host & Microbe 2019; doi:10.1016/j.chom.2019.02.005
Bulow C, Langdon A, Hink T, Wallace M, Reske KA, Patel S, Sun X, Seiler S, Jones S, Kwon JH, Burnham CA, Dantas G**, Dubberke ER**. Impact of Amoxicillin-Clavulanate followed by Autologous Fecal Microbiota Transplantation on Fecal Microbiome Structure and Metabolic Potential. mSphere 2018; doi: 10.1128/mSphereDirect.00588-18
Han X§, Sun X§, Shan X, Zhang M, Song J, Tian M, Wang S, Tong Y, Ding C, Yu S. In vivo-induced argininosuccinate lyase plays a role in the replication of Brucella abortus in RAW264.7 cells. Microbiology, 2014; 160(Pt 3):567-75(§, co-first author)
Han X, Tong Y, Tian M, Sun X, Wang S, Ding C, Yu S. Enzymatic activity analysis and catalytic essential residues identification of Brucella abortus malate dehydrogenase. The Scientific World Journal, 2014; 2014:973751
Han X, Tong Y, Tian M, Sun X, Wang S, Ding C, Yu S. Characterization of the immunogenicity and pathogenicity of malate dehydrogenase in Brucella abortus. World J Microbiol Biotechnol, 2014 Jul;30(7):2063-70
Zhang M, Han X, Liu H, Tian M, Ding C, Song J, Sun X, Liu Z, Yu S. Inactivation of the ABC transporter ATPase gene in Brucella abortus strain 2308 attenuated the virulence of the bacteria. Vet Microbiol, 2013 Jun 28;164(3-4):322-9