钱淑文 - 复旦大学 - 基础医学院

个人简介

教育经历 1996.09—2001.07 苏州大学医学院本科生 2001.09—2004.07 复旦大学医学院硕士研究生 2006.09—2009.07 复旦大学生物医学研究院博士研究生工作经历 2004.08—2006.08 上海市南方模式生物研究中心助理研究员 2009.07—2014.12 复旦大学基础医学院助理研究员 2014.12—至今复旦大学基础医学院副研究员获得奖项 2016，自然科学二等奖，教育部

研究领域

脂肪发育和代谢功能

近期论文

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Wang YN, Tang Y, He Z, Ma H, Wang L, Liu Y, Yang Q, Pan D, Zhu C, Qian S*, Tang QQ*. Slit3 secreted from M2-like macrophages increases sympathetic activity and thermogenesis in adipose tissue. Nat Metab. 2021; 3(11):1536-1551. Mu W#, Qian S#, Song Y, Yang L, Song S, Yang Q, Liu H, Liu Y, Pan D, Tang Y,Tang QQ. BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis. Redox Biol. 2021; 43:101979. Qian S, Tang Y, Tang QQ. Adipose tissue plasticity and the pleiotropic roles of BMP signaling. J Biol Chem. 2021; 296:100678. Review. Zou Y, Wang YN, Ma H, He ZH, Tang Y, Guo L, Liu Y, Ding M, Qian SW*, Tang QQ*. SCD1 promotes lipid mobilization in subcutaneous white adipose tissue. J Lipid Res. 2020;61(12):1589-1604. Qian S#, Pan J#, Su Y#, Tang Y, Wang Y, Zou Y, Zhao Y, Ma H, Zhang Y, Liu Y, Guo L, Tang QQ. BMPR2 promotes fatty acid oxidation and protects white adipocytes from cell death in mice. Commun Biol. 2020;3(1):200. Zhao YX, Pan JB, Wang YN, Zou Y, Guo L, Tang QQ*, Qian SW*. Stimulation of histamine H4 receptor participates in cold-induced browning of subcutaneous white adipose tissue. Am J Physiol Endocrinol Metab. 2019;317(6):E1158-E1171. Qian SW#, Wu MY#, Wang YN, Zhao YX, Zou Y, Pan JB, Tang Y, Liu Y, Guo L, Tang QQ. BMP4 facilitates beige fat biogenesis via regulating adipose tissue macrophages. J Mol Cell Biol. 2019;11(1):14-25. Shu-wen Qian#, Yan Liu#, Jue Wang, Ji-chang Nie, Meng-yuan Wu, Yan Tang, Ya-Xin Zhao, Xi Li, Hai-yan Huang, Liang Guo, Xi-shi Liu, Cong-jian Xu, Qi-Qun Tang. BMP4 cross-talks with estrogen/ERα signaling to regulate adiposity and glucose metabolism in females. EBioMedicine, 2016;11:91-100. Yan Tang, Shu-wen Qian*, Jue Wang, Meng-yuan Wu, Ping Lu, Xi Li, Hai-yan Huang, Liang Guo, Xia Sun, Cong-jian Xu, Qi-qun Tang*. BMP4 mediates the interplay between adipogenesis and angiogenesis during subcutaneous white adipose tissue expansion. Journal of Molecular Cell Biology, 2016;8(4):302-12. Shu-wen Qian, Yan Tang, Xi Li, Yuan Liu, You-you Zhang, Hai-yan Huang, Rui-Dan Xue, Hao-yong Yu, Liang Guo, Hui-di Gao, Yan Liu, Xia Sun, Yi-ming Li, Wei-Ping Jia, Qi-qun Tang. BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis. Proc Natl Acad Sci U S A. 2013; 110(9):E798-807.