李中华 - 复旦大学 - 基础医学院

个人简介

教育经历 2004.09—2008.06 河南师范大学生物科学专业本科生 2008.09—2013.06 南开大学化学生物学专业博士研究生工作经历 2013.07—2015.09 浙江大学博士后 2017.04—2021.2 美国埃默里大学博士后 2021.3—至今复旦大学基础医学院青年副研究员获得奖项 2013，南开大学优秀毕业生

研究领域

糖组学领域，利用基于细胞工厂的糖链制备方法和糖芯片技术进行人源糖链库的制备和功能糖组学的研究糖化学生物学领域，利用酶化学联合方法富集、标记、鉴定并定量疾病相关的糖链修饰

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

M. R. Kudelka#, Z. Li#, T. A. Chernova, D. F. Smith, X. Song, R. D. Cummings, T. Ju. Cellular O-glycome reporter/amplification (CORA): analytical and preparative tools to study mucin-type O-glycans of living cells. Current Protocols. 2021 Jun;1(6): e142. doi: 10.1002/cpz1.142. (共一) Z. Li, Q. Zhang, D. Ashline, Y. Zhu, Y. Lasanajak, T. A. Chernova, V. Reinhold, R. D. Cummings, P. G. Wang, T. Ju, D. F. Smith, X. Song. Amplification and Preparation of Cellular O-glycome for Functional O-Glycomics. Analytical Chemistry, 2020, 92(15): 10390-10401. Q. Zhang#, Z. Li#, T. A. Chernova, V. Saikam, R.D. Cummings, X. Song, T. Ju, D. F. Smith, P. G. Wang. Synthesis and Characterization of Versatile O-glycan Precursors for Cellular O-glycomics. ACS Synthetic Biology. ACS Synthetic Biology. 2019, 11, 2507-2513. (共一) Z. Li, T. A. Chernova, T. Ju. Novel Technologies for Quantitative O-Glycomics and Amplification/Preparation of Cellular O-Glycans. Synthetic Glycomes. 2019, chap 16, 370-392. J. Li#, Z. Li#, X. Duan, K. Qin, L. Dang, S. Sun, L. Cai, L. C. Hsieh-Wilson, L. Wu, W. Yi. An Isotope-Coded Photocleavable Probe for Quantitative Profiling of Protein O-GlcNAcylation. ACS Chemical Biology. 2019,14,1,4-10. (共一) Q. Li#, Z. Li#, X. Duan, W. Yi. A Tandem Enzymatic Approach for Detecting and Imaging Tumor-Associated Thomsen-Friedenreich Antigen Disaccharide. Journal of the American Chemical Society. 2014, 136, 12536-9. (共一) Z. Li, W. Yi. Regulation of cancer metabolism by O-GlcNAcylation. Glycoconjugate Journal. 2014, 31, 185-91. Z. Li, T. Li, S. Dai, X. Xie, X. Ma, W. Zhao, W. Zhang, J. Li, P. G. Wang. New Insights into the Pharmacological Chaperone Activity of C2-substituted Glucoimidazoles for the Treatment of Gaucher Disease. Chembiochem. 2013, 14, 1239-1247. Z. Li, X. Zhang, X. Han, C. Feng, F. Wang, P. G. Wang, J. Shen, Y. Shi. Antitumor effects of a novel histone deacetylase inhibitor NK-HDAC-1 in breast cancer. Oncology Reports. 2013, 30, 499-505. J. Hou#, Z. Li#, Q. Fang, C. Feng, H. Zhang, W. Guo, H. Wang, G. Gu, Y. Tian, P. Liu, R. Liu, J. Lin, Y. Shi, Z. Yin, J. Shen, P. G. Wang. Discovery and Extensive in Vitro Evaluations of NK-HDAC-1: A Chiral Histone Deacetylase Inhibitor as a Promising Lead. Journal of Medicinal Chemistry. 2012, 55, 3066. (共一)