个人简介
教育经历
1995.09—2000.07 复旦大学上海医学院法医学本科
2002.09—2006.07 复旦大学上海医学院病原生物学硕士研究生
工作经历
2000.07—至今 复旦大学上海医学院病原生物学系
近期论文
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刘江霞#; 宋武慧; 熊雅婷; 丁焕平; 袁正宏* 核酸类似物PNA在HepG 2.2.15细胞中对乙型肝炎病毒复制的抑制作用。中国临床药学杂志, 2012, (06): 363-366.
Zhang, X#; Liu, J#; Hu, Y; Chen, Hi; Yuan, Z* Hyper-activated IRF-1 and STAT1 contribute to enhanced interferon stimulated gene (ISG) expression by interferon at and gamma co-treatment in human hepatoma cell. Biochimica et Biophysica Acta-Gene Structure and Expression, 2006, 1759(8-9): 417-425.
Shen F, Li Y, Wang Y, Sozzi V, Revill P, Liu J, Gao L, Yang G, Lu M, Sutter K, Dittmer U, Chen J*, Yuan Z*. Hepatitis B virus sensitivity to interferon-alpha in hepatocytes is more associated with cellular interferon response than with viral genotype.2018, Hepatology 67:1237-1252.
Zhang W, Chen J, Wu M, Zhang X, Zhang M, Yue L, Li Y, Liu J, Li B, Shen F, Wang Y, Bai L, Protzer U, Levrero M, Yuan Z*. PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation.2017, Hepatology 66:398-415.
Li J, Liu K, Liu Y, Xu Y, Zhang F, Yang H, Liu J, Pan T, Chen J, Wu M, Zhou X, Yuan Z*. Exosomes mediate the cell-to-cell transmission of IFN-alpha-induced antiviral activity.2013, Nature Immunology 14:793-803.
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