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Huang Q*, Li F*#, Hu H*, Fang Z, Gao Z, Xia G, Ng W, Khodadadi-Jamayran A, Chen T, Deng J, Zhang H, Almonte C, Labbe K, Han H, Geng K, Tang S, Freeman G, Li Y, Chen H#, Wong K#. Loss of TSC1/TSC2 sensitizes immune checkpoint blockage in non-small-cell lung cancer. Science Advances. 2022 Feb;8(5):DOI: 10.1126/sciadv.abi9533
Hu H, Khodadadi-Jamayran A, Dolgalev I, Cho H, Badri S, Chiriboga L, Zeck B, Gregorio M, Dowling C, Labbe K, Deng J, Chen T, Zhang H, Zappile P, Chen Z, Ueberheide B, Karatza A, Han H, Ranieri M, Tang S, Jour G, Osman I, Sucker A, Schadendorf D, Tsirigos A, Schalper K, Velcheti V, Huang H, Jin Y, Ji H, Poirier J, Li F#, Wong KK#. Targeting the Atf7ip-Setdb1 complex augments anti-tumor immunity by boosting tumor immunogenicity. Cancer Immunology Research. 2021 Nov;9(11):1298-1315.
Li F*, Ng W*, Luster T, Hu H, Sviderskiy V, Dowling C, Hollinshead K, Zouitine P, Zhang H, Huang Q, Ranieri M, Wang W, Fang Z, Chen T, Deng J, Zhao K, So H, Khodadadi-Jamayran A, Xu M, Karatza A, Pyon V, Li S, Pan Y, Labbe K, Poirier J, Miller G, Almonte C, Labbe K, Silver H, Rabin A, Jani K, Tsirigos A, Papagiannakopoulos T, Hammerman P, Possemato R, Qi J, Wong KK. Epigenetic CRISPR screens identify Npm1 as a therapeutic vulnerability in non-small cell lung cancer. Cancer Research. 2020 Sep 1;80(17):3556-3567. (Cover story)
Li F, Huang Q, Luster T, Hu H, Zhang H, Ng W, Khodadadi-Jamayran A, Wang W, Chen T, Deng J, Ranieri M, Fang Z, Pyon V, Dowling C, Bagdatlioglu E, Almonte C, Labbe K, Silver H, Rabin A, Jani K, Tsirigos A, Papagiannakopoulos T, Hammerman P, Velcheti V, Freeman G, Qi J, Miller G, Wong KK. In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma. Cancer Discovery. 2020 Feb;10(2):270-287. (Highlighted by Cancer Discovery. 2020 Feb;10(2):179-181.)
Li F*, Fang Z*, Zhang J*, Li Chen, Liu H, Xia J, Zhu H, Guo C, Qin Z, Li FM, Han X, Wang Y, Feng Y, Wang Y, Zhang W, Wang Z, Jin Y, Sun Y, Wei W, Zeng R, Chen H, Ji H. Identification of TRA2B-DNAH5 gene fusion as a novel oncogenic driver in human lung squamous cell carcinoma. Cell Research. 2016; 26 (10):1149-1164.
Li FM*, Han X*, Li F*, Wang R, Wang H, Gao Y, Wang X, Fang Z, Zhang W, Yao S, Tong X, Wang Y, Feng Y, Sun Y, Li Y, Wong KK, Zhai Q, Chen H, Ji H. LKB1 inactivation elicits a redox imbalance to modulate non-small cell lung cancer plasticity and therapeutic response. Cancer Cell. 2015. 27(5):698-711. (Cover story)
Li F*, Feng Y*, Fang R*, Fang Z, Xia J, Han X, Liu XY, Chen H, Liu H, Ji H. Identification of RET gene fusion by exon array analyses in 'pan-negative' lung adenocarcinomas from never smokers. Cell Research.2012;22(5):928-31.