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个人简介

教育经历 2002.09—2006.06 武汉大学 生命科学院 本科生 2007.09—2012.12 复旦大学 生命科学院 博士研究生 工作经历 2013.07—2016.09 复旦大学 基础医学院 博士后 2016.10—2018.11 加州大学旧金山分校 生理学系 博士后 2019.01—至今 复旦大学基础医学院 青年研究员 获得奖项 2020,教育部高等学校科学研究优秀成果奖(科学技术)二等奖

研究领域

压力应激蛋白在疾病进程中的作用机制 氧气应激介导的蛋白质脯氨酸羟基化修饰调控机制及干预

近期论文

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Y. Liu#, H. Cheng#, C. Cheng, F. Zheng, Z. Zhao, Q. Chen, W. Zeng, P. Zhang, C. Huang*, W. Jiang*, X. Liu*, G. Liu*, ZNF191 alters DNA methylation and activates the PI3K-AKT pathway in hepatoma cells via transcriptional regulation of DNMT1, Cancer Med, (2022) Online. X. Wang#, W. Jiang#, S. Luo, X. Yang, C. Wang, B. Wang, Y. Dang, Y. Shen, D.K. Ma, The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex, Mol Brain, 14 (2021) 54. R. Tan, W. Du, Y. Liu, X. Cong, M. Bai, C. Jiang, Z. Li, M. Tan, D. K. Ma, Q. Huang*, W. Jiang*, Y. Dang*. Nucleolus localization of SpyCas9 affects its stability and interferes with host protein translation in mammalian cells, Genes & Diseases, (2020) Online. Y. Liu#, D. Wu#, H. Cheng, L. Chen, W. Zhang, L. Zou, Q. Gao, Z. Zhao, Q. Chen, W. Zeng, Z. Zhang, W. Jiang*, C. Huang*, G. Liu*, Wnt8B, transcriptionally regulated by ZNF191, promotes cell proliferation of hepatocellular carcinoma via Wnt signaling, Cancer Sci, (2020). D. Ding#, H. Huang#, Q. Li#, W. Yu, C. Wang, H. Ma, J. Wu, Y. Dang, L. Yu*, W. Jiang*, NF90 stabilizes cyclin E1 mRNA through phosphorylation of NF90-Ser382 by CDK2, Cell Death Discov, 6 (2020) 3. X. Lin#, Y. Liu#, A. Bai#, H. Cai#, Y. Bai, W. Jiang, H. Yang, X. Wang, L. Yang*, N. Sun*, H. Gao*, A viscoelastic adhesive epicardial patch for treating myocardial infarction, Nat Biomed Eng, 3 (2019) 632-643. W. Jiang#, X. Zhou#, Z. Li#, K. Liu, W. Wang, R. Tan, X. Cong, J. Shan, Y. Zhan, Z. Cui, L. Jiang, Q. Li, S. Shen, M. Bai, Y. Cheng, B. Li, M. Tan, D.K. Ma, J.O. Liu, Y. Dang*, Prolyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin, Blood, 131 (2018) 1325-1336. W. Jiang#, Y. Wei#, Y. Long#, A. Owen, B. Wang, X. Wu, S. Luo, Y. Dang, D.K. Ma*, A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans, Elife, 7 (2018). doi:10.7554/eLife.35037 (2018). D. Ding#, H. Huang#, W. Jiang, W. Yu, H. Zhu, J. Liu, H. Saiyin, J. Wu, H. Huang, S. Jiang*, L. Yu*, Reticulocalbin-2 enhances hepatocellular carcinoma proliferation via modulating the EGFR-ERK pathway, Oncogene, 36 (2017) 6747-6748. W. Jiang, H. Huang, L. Ding, P. Zhu, H. Saiyin, G. Ji, J. Zuo, D. Han, Y. Pan, D. Ding, X. Ma, Y. Zhang, J. Wu, Q. Yi, J.O. Liu, H. Huang, Y. Dang*, L. Yu*, Regulation of cell cycle of hepatocellular carcinoma by NF90 through modulation of cyclin E1 mRNA stability, Oncogene, 34 (2015) 4460-4470.

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