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Guan R, Pan M, Xu X#,Du L, Rao X, Fu G, Lv T, Zhang L, Li Y, Tang P, Zhou Y, Wang Y, Zhang Z, Gao J, Zhou H, Mi W, Hua G. Interleukin-33 potentiates TGF-b signaling to regulate intestinal stem cell regeneration after radiation injury. Cell Transplant. 2023 Jan-Dec; 32:9636897231177377.
Lv T, Shen L, Xu X#, Yao Y, Mu P, Zhang H, Wan J, Wang Y, Guan R, Li X, Fu G, Zhang L, Wang Y, Xia F, Hu C, Clevers H, Zhang Z, Hua G. Patient-derived tumor organoids predict responses to irinotecan-based neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer. Int J Cancer. 2023 Feb 1;152(3):524-535
Mo S, Tang P, Luo W, Zhang L, Li Y, Hu X, Ma X, Chen Y, Bao Y, He X, Fu G, Xu X, Rao X, Li X, Guan R, Chen S, Deng Y, Lv T, Mu P, Zheng Q, Wang S, Liu F, Li Y, Sheng W, Huang D, Hu C, Gao J, Zhang Z, Cai S, Clevers H, Peng J, Hua G. Patient-derived organoids from colorectal cancer with paired liver metastasis reveal tumor heterogeneity and predict response to chemotherapy. Adv Sci (Weinh), 2022 Sep 4:2204097.
Li X, Fu G, Zhang L, Guan R, Tang P, Zhang J, Rao X, Chen S, Xu X, Zhou Y, Deng Y, Lv T, He X, Mo S, Mu P, Gao J, Hua G. Assay establishment and validation of a high-throughput organoid-based drug screening platform. Stem Cell Res Ther. 2022 May 26;13(1):219.
Hong W, Tang L, Ge R, Li W, Shen X, Hong L, Xu X*. Persistent abnormal immunocytes induced systemic bone loss in locally irradiated rats. Calcif Tissue Int, 2021 Dec; 109(6):706-718.
Rao X, Tang P, Li Y, Fu G, Chen S, Xu X, Zhou Y, Li X, Zhang L, Mo S, Cai S, Peng J, Zhang Z, Gao J, Hua G. CBP/P300 inhibitors mitigate radiation-induced GI syndrome by promoting intestinal stem cell-mediated crypt regeneration. Int J Radiat Oncol Biol Phys. 2021 Jul 15;110(4):1210-1221.
Li Y, Rao X, Tang P, Chen S, Guo Q, Fu G, Pan M, Liang L, Yao Y, Gao X, Zhou Y, Zhang Z, Xu X, Hu W, Gao J, Hua G. Bach2 deficiency promotes intestinal epithelial regeneration by accelerating DNA repair in intestinal stem cells. Stem Cell Reports, 2021 Jan 12;16(1)120-133.
Fu G, Chen S, Liang L, Li X, Tang P, Rao X, Pan M, Xu X, Li Y, Yao Y, Zhou Y, Gao J, Mo S, Cai S, Peng J, Zhang Z, Clevers H, Gao J, Hua G. SIRT1 inhibitors mitigate radiation-induced GI syndrome by enhancing intestinal stem-cell survival. Cancer Lett. 2021 Mar 31;501:20-30.
Ye Yao, Xiaoya Xu#, Lifeng Yang, Ji Zhou, Juefeng Wan, Lijun Shen, Fan Xia, Guoxiang Fu, Yun Deng, Menxue Pan, Qiang Guo, Xiaoxue Gao, Yuanchuang Li, Xinxin Rao, Yi Zhou, Liping Liang, Yaqi Wang, Jing Zhang, Hui Zhang, Lixing Zhang, Junjie Peng, Sanjun Cai, Chen Hu, Jianjun Gao, Hans Clevers, Zhen Zhang, Guoqiang Hua. Patient-derived organoids predict chemoradiation responses of locally advanced rectal cancer. Cell Stem Cell. 2020 Jan 2;26(1):17-26.
Li Y, Li J, Wang R, Zhang L, Fu G, Wang X, Wang Y, Fang C, Zhang D, Du D, Ma X, Pan M, Guo Q, Xu X, Hu X, Zhou Y, Mo S, Wang H, Gao J, Huang S, Liu Y, Cao S, Hua G, Peng J, Yu FX. Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma. Protein Cell. 2020 Apr;11(4)292-298.
Hu X, Zhang L, Li Y, Ma X, Dai W, Gao X, Rao X, Fu G, Wang R, Pan M, Guo Q, Xu X, Zhou Y, Gao J, Zhang Z, Cai S, Peng J, Hua G. Organoid modelling identifies that DACH1 functions as a tumor promoter in colorectal cancer by modulating BMP signaling. EBioMedicine. 2020 Jun; 56:102800.
Li Y, Wang R, Huang D, Ma X, Mo S, Guo Q, Fu G, Li Y, Xu X, Hu X, Zhou Y, Deng Y, Zhang L, Chen H, Gao J, Zhang Z, Cai S, Hua G, Peng J. A novel human colon signet-ring cell carcinoma organoid line: establishment, characterization and application. Carcinogenesis, 2020 Jul 14;41(7):993-1004.
Hong W, Wei Z, Qiu Z, Li Z, Fu C, Ye Z, Xu X*. Atorvastatin promotes bone formation in aged apoE-/- mice through the Sirt1-Runx2 axis. J Orthop Surg Res. 2020 Aug 6;15(1):303.
Zhang L, Mo S, Hu X, Ma X, Jin W, Peng DH, Zhou Y, Liang X, Rao X, Xu X, Zhang Z, Hua G, Cai S, Li Y, Peng J. Establishment and identification of organoids from human circulating colorectal cancer cells. Clin Transl Med. 2020 Dec;10(8):e247.
Guo Q, Chen S, Rao X, Li Y, Pan M, Fu G, Yao Y, Gao X, Tang P, Zhou Y, Xu X, Gao J, Hua G. Inhibition of SIRT1 promotes taste bud stem cell survival and mitigates radiation induced oral mucositis in mice. Am J Transl Res,2019 Aug 15;11(8):4789-4799.
Mengxue Pan, Wei Hong, Ye Yao, Xiaoxue Gao, Yi Zhou, Guoxiang Fu,Yuanchuang Li, Qiang Guo, Xinxin Rao, Peiyuan Tang, Shengzhi,Chen, Weifang Jin, Guoqiang Hua, Jianjun Gao and Xiaoya Xu*. Activated B lymphocyte inhibited the osteoblastogenesis of bone mesenchymal stem cells by Notch signaling. Stem Cell Int,2019 Jun 2;2019:8150123.
Xiaoya Xu#, Ruixia Li, Yi Zhou, Qiong Zou, Qiaoling Ding, Jinfeng Wang, Weifang Jin, Guoqiang Hua, Jianjun Gao*. Dysregulated systemic lymphocytes affect the balance of osteogenic/adipogenic differentiation of bone mesenchymal stem cells after local irradiation. Stem Cell Res Ther, 2017,8(1):71
Changjun Guo#, Changwei Li, KaiYang, Xiaoya Xu*, Xiangyang Xu*, Lianfu Deng*. Increased EZH2 and decreased osteoblastogenesis during local irradiation-induced bone loss in rats. Scientific Reports, 2016,6:31318
Qiong Zou#, Wei Hong,Yi Zhou, Qiangling Ding, Jinfeng Wang, Weifang Jin, Jianjun Gao, Guoqiang Hua, Xiaoya Xu*. Bone marrow stem cell dysfunction in radiation-induced abscopal bone loss. Journal of Orthopaedic Surgery and Research. 2016,11:3
Wei Hong#, Xiaoya Xu, Zhaohui Qiu, Jianjun Gao, Zhanying Wei, Zhen Li, Xiaoli Zhang, Zhibing Ye*. Sirt1 is involved in decreased bone formation in aged apolipoprotein E-deficient mice. Acta Pharmacologica Sinica. 2015,36(12):1487-96
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