沈波 - 复旦大学 - 放射医学研究所

个人简介

沈波，博士、副研究员。2006年获吉林大学放射医学博士学位，2008年在美国哥伦比亚大学辐射研究中心从事博士后研究工作，曾主持国家自然科学基金青年项目、面上项目及国家重点实验室开放性课题等多个项目。主持科研项目沈波，核靶向多功能纳米颗粒增强DNA辐射损伤的实验性，国家自然科学基金面上资助项目（2017-2020，81672986），直接经费55万元沈波，单粒子微束照射诱导p53 依赖的辐射旁效应与细胞能量代谢的相关性研究，国家自然科学基金青年项目（2011-2014，11105031），直接经费26万元沈波，新型多功能纳米诊疗剂联合放射治疗用于乏氧肿瘤高效诊疗的实验研究，高性能陶瓷和超微结构国家重点实验室开放课题基金（2015-2016，SKL201410SIC），10万元

近期论文

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Ma, Shulan; Li, Dongju; Jiang, Jianwei; Shen, Bo(*) Role of the medial preoptic area in electroacupuncture treatment of reproductive dysfunction in ovariectomised rats, Acupuncture in medicine, 2017, 2, 35(1). He, Peijie, Shen, Bo, Chung, Aha, Liang, Zhou, Photosensitizer Effect of 9-hydroxypheophorbide α on Diode Laser-Irradiated Laryngeal Cancer Cells: Oxidative Stress-Directed Cell Death and Migration Suppression. Oncol Lett. 2016 Sep; 12(3): 1889-1895. doi: 10.3892/ol.2016.4889. Fan Wenpei, Shen, Bo(#), Bu,Wenbo, Zheng, Xiangpeng, He, Qianjun, Cui,Zhaowen, Ni,Dalong , Zhao, Kuaile, Zhang Shengjian , Shi, Jianlin , Intranuclear biophotonics by smart design of nuclear-targeting photo-/radio-sensitizers co-loaded upconversion nanoparticles, Biomaterials, 2015/11, 89-98. Ma, Shu-Lan, Jia, Rong-Fei, Li, Dong-Ju, Shen, Bo(*), Targeting Cellular Metabolism Chemosensitizes the Doxorubicin-Resistant Human Breast Adenocarcinoma Cells, Biomed Res Int, 2015, 2015(1), 453986. Shen, Bo(#)(*)，Zhao, Kuaile，Ma, Shulan，Yuan, Dexiao，Bai, Yang，Topotecan-loaded mesoporous silica nanoparticles for reversing multi-drug resistance by synergetic chemoradiotherapy.，Chem Asian J., 2015, 10(2): 344-348. Fan, Wenpei(#)，Shen Bo(#)，Bu, Wenbo(*)，Chen, Feng，He, Qianjun，Zhao, Kuaile，Zhang, Shengjian，Zhou, Liangping，Peng, Weijun，Xiao, Qingfeng，Ni, Dalong，Liu, Jianan，Shi, Jianlin(*)，A smart upconversion-based mesoporous silica nanotheranostic system for synergetic chemo-/radio-/photodynamic therapy and simultaneous MR/UCL imaging.，Biomaterials, 2014, 35(32): 8992-9002. Zhang Huankang(#), Shen Bo(#), Swinarska, Joanna T., Li Wen, Xiao Kuanlin(*), He Peijie, 9-Hydroxypheophorbide alpha-mediated photodynamic therapy induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in Hep-2 cells via ROS-mediated suppression of the ERK pathway, Photodiagnosis and Photodynamic Therapy, 2014, 11(1): 55-62. Zhang Huankang, Shen, Bo(#), Swinarska, Joanna T, Li Wen, Xiao Kuanlin, He Peijie, 9-Hydroxypheophorbide α-mediated photodynamic therapy induces matrix metalloproteinase-2 and MMP-9 downregulation in Hep2 cells, Photodiagnosis Photodyn Ther, 2014/3, 11(1):55-62. Liao, Jiongbo(#); Wang, Xiao; Bi, Yujing; Shen, Bo; Shao, Kun; Yang, Hui; Lu, Yun; Zhang, Zhengguo; Chen, Xi; Liu, Huanrong; Wang, Jian; Chu, Yiwei; Xue, Lixiang(*); Wang, Xianghui(*); Liu, Guangwei(*); Dexamethasone potentiates myeloid-derived suppressor cell function in prolonging allograft survival through nitric oxide, Journal of Leukocyte Biology, 2014, 96(5): 675-684. Liu, Guangwei(*); Bi, Yujing; Shen, Bo; Yang, Hui; Zhang, Yan; Wang, Xiao; Liu, Huanrong; Lu, Yun; Liao, Jiongbo; Chen, Xi; Chu, Yiwei; SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1 alpha-Dependent Glycolysis, Cancer Research, 2014, 74(3): 727-737. Shen, Bo(#)(*); He, Pei-Jie; Shao, Chun-Lin; Norcantharidin Induced DU145 Cell Apoptosis through ROS-Mediated Mitochondrial Dysfunction and Energy Depletion, PLos One, 2013, 8(12). Fan, Wenpei(#); Shen, Bo(#); Bu, Wenbo(*); Chen, Feng; Zhao, Kuaile; Zhang, Shengjian; Zhou, Liangping; Peng, Weijun; Xiao, Qingfeng; Xing, Huaiyong; Liu, Jianan; Ni, Dalong; He, Qianjun; Shi, Jianlin; Rattle-Structured Multifunctional Nanotheranostics for Synergetic Chemo-/Radiotherapy and Simultaneous Magnetic/Luminescent Dual-Mode Imaging, Journal of the American Chemical Society, 2013, 135(17): 6494-6503. Li, Jitao(#); He, Mingyuan; Shen, Bo; Yuan, Dexiao; Shao, Chunlin; Alpha particle-induced bystander effect is mediated by ROS via a p53-dependent SCO2 pathway in hepatoma cells., International Journal of Radiation Biology, 2013, 89(12): 1028-1034. Liu, Guangwei(#)(*); Bi, Yujing; Wang, Ruoning; Shen, Bo; Zhang, Yan; Yang, Hui; Wang, Xiao; Liu, Huanrong; Lu, Yun; Han, Fei; Kinase AKT1 negatively controls neutrophil recruitment and function in mice, The Journal of Immunology, 2013, 191(5): 2680-2690. He, Mingyuan; Zhao, Meijia; Shen, Bo; Prise, K. M.; Shao, Chunlin(*); Radiation-induced intercellular signaling mediated by cytochrome-c via a p53-dependent pathway in hepatoma cells, ONCOGENE, 2011, 30(16): 1947-1955.