当前位置: X-MOL首页全球导师 国内导师 › 孔星星

个人简介

教育及工作经历 2021–至今 复旦大学生命科学学院 教授; 复旦附属华山医院 特聘教授 2017–2021美国加州大学洛杉矶分校 助理教授 2015–2017 哈佛大学贝斯以色列女执事医学中心(美国)讲师 2011–2015 哈佛大学贝斯以色列女执事医学中心(美国)博士后 2006-2011 中国医学科学院&北京协和医学院 博士 2001-2006 中国医科大学 医学本科

研究领域

组织器官代谢与网络调控

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Guo S, Feng Y, Zhu X, Zhang X, Wang H, Wang R, Zhang Q, Li Y, Ren Y, Gao X, Bian H #, Liu T #, Gao H #, Kong X#. Metabolic crosstalk between skeletal muscle and liver through IRF4-FSTL1 in NASH. Nature Communications. 14(1):6047, 2023. PMID: 37770480. Zhang S, Yan H, Ding J, Wang R, Feng Y, Zhang X, Kong X, Gong H, Lu X, Ma A, Hua Y, Liu H, Guo J, Gao H, Zhou Z, Wang R#, Chen P#, Liu T#, Kong X#. Skeletal muscle-specific DJ-1 ablation-induced atrogenes expression and mitochondrial dysfunction contributing to muscular atrophy. J. Cachexia Sarcopenia Muscle. 14(5):2126-2142, 2023. PMID: 37469245.影响因子=12.063 Guo S, Zhang S, Zhuang Y, Xie F, Wang R, Kong X, Zhang Q, Feng Y, Gao H, Kong X#, Liu T#. Muscle PARP1 inhibition extends lifespan through AMPKα PARylation and activation in Drosophila. Proc Natl Acad Sci U S A. 120: e2213857120, 2023. PMID: 3694751. 影响因子=12.77 Feng Y, Cui Z, Lu X, Gong H, Liu X, Wang H, Cheng H, Gao H, Shi X, Li Y, Ye H, Zhang Q#, Kong X#. Transcriptomics Dissection of Calorie Restriction and Exercise Training in Brown Adipose Tissue and Skeletal Muscle. Nutrients. 15: 1047, 2023. PMID: 36839405.影响因子=6.7 Yao T, Yan H, Zhu X, Zhang Q, Kong X, Guo S, Feng Y, Wang H, Hua Y, Zhang J, Mittelman S, Tontonoz P, Zhou Z, Liu T, Kong X. Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome. Diabetes. 71:2256–2271, 2022. PMID: 35713959.影响因子=9.337 Bao K*, Cui Z*, Wang H, Xiao H, Li T, Kong X#, Liu T#. Pseudotime Ordering Single-Cell Transcriptomic of β Cells Pancreatic Islets in Health and Type 2 Diabetes.Phenomics. 199-210, 2021. Zhu X*, Yao T*, Wang R*, Guo S, Wang X, Zhou Z, Zhang Y, Zhou X, Zhang Y, Zhuo X, Wang RT, Li ZJ#, Liu T#, Kong X#. IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway. Advanced Science. 7(19):2001502, 2020. PMID: 33042761.影响因子=15.804 Wang R*, Tian H*, Guo D, Tian Q, Yao T#, Kong X#. Impacts of Exercise Intervention on Various Diseases in Rats. J of Sport and Health Science. 9(3):211-227, 2020. (Review) PMID: 32444146. 影响因子=5.2,一区 Kong X*#, Yao T*, Zhou P, Kazak L, Tenen D, Lyubetskaya A, Tsai L, Kahn BB, Spiegelman BM, Liu T# and Rosen ED#. Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin. Cell Metabolism. 28:631–643, 2018. (* 共同第一作者,#共同通讯作者) PMID:30078553. 影响因子=22.415 Kong X, Banks AS, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM and Rosen ED. IRF4 is a key thermogenic transcriptional partner of PGC-1a. Cell. 158(1), 69-83, 2014. PMID: 24995979. 影响因子=33.116 Williams KW*#, Liu T*, Kong X*, Fakuda M*, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW, Jia L, Fujikawa T, Kohno D, Scott MM, Lee S, Lee CE, Sun K, Chang Y, Scherer PE and Elmquist JK. Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metabolism.20(3):471-82. 2014. (* 共同第一作者) PMID:25017942. 影响因子=18.878 Berglund ED*, Liu T*, Kong X*, Sohn JW, Vong L, Deng Z, Lee CE, Lee S, Olson DP, Scherer PE, Lowell BB#, and Elmquist JK#. Melanocortin-4 receptors in preg Williams KW,anglionic parasympathetic and sympathetic neurons differentially control energy balance and glucose homeostasis. Nature Neuroscience. 17(7):911-3. 2014. (* 共同第一作者) PMID:24908101. 影响因子=16.095 Eguchi J*, Kong X*, Tenta M, Wang X, Kang S, and Rosen ED. Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization. Diabetes. 62(10):3394-403. 2013(* 共同第一作者) PMID: 23835343. 影响因子=8.474 Kong X*, Wang R,Xue Y, Liu X, Zhang H, Chen Y,Fang F#, Chang Y#.Sirtuin 3, a new target of peroxisome proliferator-activated receptor-γ coactivator-1α, plays an important role in the suppression of reactive oxygen species. PLos One. 5(7): e11707, 2010. Kong X*, Wang R, Liu X, Zhu L, Shao D, Chang Y#, and Fang F#. Function of SIRT1 in Physiology.Biochemistry (Moscow). 74(7): 703–708, 2009. (review) Kong X*, Fan H*, Liu X, Wang R, Liang J, Gupta N, Chen Y#, Fang F#, Chang Y#. Peroxisome Proliferator-Activated Receptor Coactivator-1Enhances Antiproliferative Activity of 5-Deoxy-5-Fluorouridinein Cancer Cells through Induction of Uridine Phosphorylase. Mol Pharmacol.76:854–860, 2009. (* 共同第一作者)

推荐链接
down
wechat
bug