个人简介
焦娜,青年研究员,博士生导师。2014年毕业于吉林大学获得工学学士学位,2019年在同济大学获得生物学博士(生物信息学方向),2019-2021年在中山大学附属第六医院进行博士后研究。2021-2023年在浙江大学医学院附属儿童医院国家儿童健康与疾病临床医学研究中心任特聘研究员,2024年1月入职复旦大学生科院微生物学与免疫学系,任青年研究员。研究聚焦于微生物与宿主互作、微生物资源挖掘和微生物组学分析方法及平台开发。近年来围绕微生物与慢病防治、微生物-宿主互作在Nature Microbiology、Nature Communications、Cell Reports Medicine、Gut和Gut Microbes等期刊上发表了多篇研究论文。入选博士后创新人才支持计划和获得国家自然科学基金青年科学基金项目资助。
研究领域
微生物与宿主互作
微生物资源挖掘
微生物组学分析方法及平台开发
近期论文
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Xinyue Zhu#, Pingping Xu#, Ruixin Zhu*, Wenxing Gao, Wenjing Yin, Ping Lan, Lixin Zhu*, Na Jiao*, Multi-kingdom microbial signatures in excess body weight colorectal cancer based on global metagenomic analysis, Communications Biology, 2024, 10.1038/s42003-023-05714-0
Wenxing Gao#, Xiang Gao#, Lixin Zhu*, Sheng Gao, Ruicong Sun, Zhongsheng Feng, Dingfeng Wu, Zhanju Liu*, Ruixin Zhu*, Na Jiao*, Multimodal metagenomic analysis reveals microbial single nucleotide variants as superior biomarkers for early detection of colorectal cancer. Gut Microbes, 2023, 15(2):2245562.
Xiang Gao#, Ruicong Sun#, Na Jiao#, Xiao Liang, Gengfeng Li, Han Gao, Xiaohan Wu, Muqing Yang, Chunqiu Chen, Liang Chen, Wei Wu, Zhong Li, Yingzi Cong, Ruixin Zhu*, Tiannan Guo*, Zhanju Liu*, Integrative multi-omics deciphers the spatial characteristics of host-gut microbiota interactions in Crohn’s disease. Cell Reports Medicine. 2023;4, 101050.
Ningning Liu#, Na Jiao#, Jing-Cong Tan#, Ziliang Wang#, Dingfeng Wu, An-Jun Wang, Jie Chen, Liwen Tao, Chenfen Zhou, Wenjie Fang, Io Hong Cheong, Weihua Pan, Wanqing Liao, Zisis Kozlakidis, Christopher Heeschen, Geromy G. Moore, Lixin Zhu*, Xingdong Chen*, Guoqing Zhang*, Ruixin Zhu*, Hui Wang*. Multi-kingdom microbiota analyses identify bacterial-fungal interactions and biomarkers of colorectal cancer across cohorts. Nature Microbiology, 2022; 7(2):238-250. (ESI)
Dingfeng Wu#, Lei Liu#, Na Jiao#, Yida Zhang, Li Yang, Chuan Tian, Ping Lan, Lixin Zhu*, Rohit Loomba*, and Ruixin Zhu*. Targeting Keystone Species Helps Restore the Dysbiosis of Butyrate‐Producing Bacteria in Nonalcoholic Fatty Liver Disease. iMeta. 2022 1(4): e61
Yuqi Wu#, Na Jiao#, Ruixin Zhu*, Yida Zhang, Dingfeng Wu, An-Jun Wang, Sa Fang, Liwen Tao, Yichen Li, Sijing Cheng, Ping Lan, Chuan Tian*, Ning-Ning Liu*, Lixin Zhu*. Identification of microbial markers across populations in early detection of colorectal cancer. Nature Communications, 2021; 12(1):3063. (ESI)
Na Jiao, Susan S Baker*, Adrian Chapa-Rodriguez, Wensheng Liu, Colleen A Nugent, Maria Tsompana, Lucy Mastrandrea, Michael J Buck, Robert D Baker, Robert J Genco, Ruixin Zhu*, Lixin Zhu*. Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD. Gut. 2018; 67(10):1881-1891 (ESI)
Na Jiao#, Susan S. Baker, Colleen A. Nugent, Maria Tsompana, Liting Cai, Yong Wang, Michael J. Buck, Robert J. Genco, Robert D. Baker, Ruixin Zhu*, Lixin Zhu*. Gut microbiome may contribute to insulin resistance and systemic inflammation in obese rodents: a meta-analysis. Physiological Genomics. 2018; 50(4):244-254. (APSselectaward)