冯会娟 - 复旦大学 - 生命科学学院

个人简介

2011年获华中科技大学生物信息技术专业学士学位，2016年获清华大学生物信息学专业博士学位，2016年至2021年在美国哥伦比亚大学系统生物学系从事博士后研究，2022年加入复旦大学生命科学学院，任青年研究员，博士生导师。

研究领域

融合生物信息学方法开发和高通量多组学数据建模，分析和挖掘，聚焦疾病和发育中可变剪接的功能和调控机制，并针对剪接相关疾病，探索其RNA治疗方法

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Feng H, Moakley DF, Chen S, McKenzie MG, Menon V, Zhang C. Complexity and graded regulation of neuronal cell type-specific alternative splicing revealed by single-cell RNA sequencing. PNAS, 2021; 118(10). Feng H*, Bao S*, Weyn-Vanhentenryck SM, Khan A, Wong J, Shah A, Flynn ED, Zhang C. Modeling the in vivo specificity of RNA-binding proteins by precisely registering protein-RNA crosslink sites. Molecular Cell. 2019;74 (6), 1189-1204. e6. Weyn-Vanhentenryck SM*, Feng H*, Ustianenko D, Duffie R, Yan Q, Jacko M, Martinez JC, Goodwin M, Zhang X, Hengst U, Lomvardas S, Swanson MS, Zhang C. Precise temporal regulation of alternative splicing during neural development. Nature Communications. 2018;9(1):2189. Feng H, Li T, Zhang X. Characterization of kinase gene expression and splicing profile in prostate cancer with RNA-Seq data. BMC Genomics. 2018;19(6):153. Feng H, Zhang X, Zhang C. mRIN for direct assessment of genome-wide and gene-specific mRNA integrity from large-scale RNA-sequencing data. Nature Communications. 2015;6:7816. Feng H, Qin Z, Zhang X. Opportunities and methods for studying alternative splicing in cancer with RNA-Seq. Cancer Letters. 2013;340(2):179-91. Jacko M, Weyn-Vanhentenryck SM, Smerdon JW, Yan R, Feng H, Williams DJ, Pai J, Xu K, Wichterle H, Zhang C. Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly. Neuron. 2018;97(4):853-68 e6. Genestine M, Ambriz D, Crabtree GW, Dummer P, Molotkova A, Quintero M, Mela A, Biswas S, Feng H, Zhang C, Canoll P, Hargus G, Agalliu D, Gogos JA, Au E. Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons. Elife. 2021; 10, e56063. Oku S, Feng H, Connor S, Toledo A, Zhang P, Zhang Y, Thoumine O, Zhang C, Craig AM. Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity. Elife. 2020; 9, e58668.