个人简介
男,博士,硕士生导师。2015年6月博士毕业于复旦大学生物医学研究院,同年于复旦大学脑科学研究院进行博士后训练(2015.7-2017.11),2017年12月起任复旦大学生命科学院青年副研究员、副研究员。
获奖情况
长三角神经科学青年科学家奖(2020);Sanofi-Cell Research年度杰出论文奖(2022)
研究领域
自噬和脂自噬机制与应用;聚谷氨酰胺(polyQ)疾病和聚甘氨酸(polyG)疾病发生机制与干预
近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
Ningxie Chen; Boxun Lu*; Yuhua Fu* ; Autophagic Clearance of Lipid Droplets Alters Metabolic Phenotypes in a Genetic Obesity–Diabetes Mouse Model, Phenomics,2022 Nov 19;3(2):119-129.(封面论文,*Co-corresponding author)
Fu, Yuhua; Chen, Ningxie; Wang, Ziying; Luo, Shouqing; Ding, Yu; Lu, Boxun ; Degradation of lipid droplets by chimeric autophagy-tethering compounds, Cell Research, 2021, 31(9): 965-979.(封面论文,Sanofi-Cell Research 2021年度杰出论文)
Xiaodan Zhang; Xue Wen; Ismael Al-Ramahi; Juan Botas; Boxun Lu;Yuhua Fu ; Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy, Neuroscience Bulletin, 2021, 38(1): 99-103.
Xiao-jing Li#; Yuan-yuan Zhang#;Yu-hua Fu#; Hao Zhang; He-xuan Li;Quan-fu Li; Hai-ling Li; Ren-ke Tan; Chen-xiao Jiang; Wei Jiang; Zeng-xia Li;Cheng Luo; Bo-xun Lu; Yong-jun Dang; Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex, Acta Pharmacologica Sinica, 2021, 42(1): 1-11. (#co-first author)
Yuhua Fu#; Peng Wu#; Yuyin Pan#; Xiaoli Sun#; Huiya Yang; Marian Difiglia; Boxun Lu; A toxic mutant huntingtin species is resistant to selective autophagy, Nature Chemical Biology, 2017, 13(11): 1152-1154. (#co-first author)
Meng Yu#; Yuhua Fu#; Yijiang Liang#; Haikun Song; Yao Yao; Peng Wu;Yuwei Yao; Yuyin Pan; Lixiang Ma; Saiyin Hexige; Yu Ding; Shouqing Luo; Boxun Lu; Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models, Cell Research, 2017, 27(12): 1441-1665.(#co-first author)