个人简介
陈静影,女,青年研究员,博士生导师,国家优秀青年科学基金获得者。2016年毕业于西南大学获得博士学位,2019-2023年在中国科学院重庆绿色智能技术研究院先后任特别研究助理、副研究员,2023年加入复旦大学生命科学学院任青年研究员。先后主持国家优秀青年科学基金项目、国家自然科学基金青年科学基金项目等。
研究领域
本课题组以斑马鱼和小鼠为主要模式动物,以脑血管再生修复的细胞基础和分子机制为主要研究方向,着重探讨脑血管再生修复的物种差异机制
近期论文
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Zhanmei Jiang, Lirong Huang, Jieqiong Zhao, Yanfeng Li, Jianlong Ma, Rui Ni, Qifen Yang, Lingfei Luo, Yun Yang*, Jingying Chen*. GoldenFish: a rapid and efficient system to customize constructs for zebrafish transgenesis. Journal of Molecular Cell Biology. 2023 Apr 20;14(12):mjac075. (IF=8.19)
Chuan Wu, Da Zhang, Jingying Chen*. Microtubules are essential for angiogenic sprout elongation in zebrafish. Journal of Genetics and Genomics. 2023 Feb;50(2):126-129. (IF=5.72)
Yuhang Xu, Lingfei Luo, Jingying Chen*. Sulfamethoxazole induces brain capillaries toxicity in zebrafish by up-regulation of VEGF and chemokine signalling. Ecotoxicology and Environmental Safety. 2022, 238: 113620-113620. (IF=7.129)
Jingying Chen, Jianbo He, Lingfei Luo*. Brain vascular damage-induced lymphatic ingrowth is directed by Cxcl12b/Cxcr4a. Development. 2022 Jul 1;149(13):dev200729. (IF=6.862).
Jingying Chen#, Xiuhua Li#, Rui Ni, Qi Chen, Qifen Yang, Jianbo He, Lingfei Luo*. Acute brain vascular regeneration occurs via lymphatic transdifferentiation. Developmental Cell. 2021 Nov 22;56(22):3115-3127.e6. (IF=13.417)
Jingying Chen, Jianbo He, Rui Ni, Qifen Yang, Yaoguang Zhang, Lingfei Luo*. Cerebrovascular Injuries Induce Lymphatic Invasion into Brain Parenchyma to Guide Vascular Regeneration in Zebrafish. Developmental Cell. 2019 Jun 3;49(5):697-710.e5. (IF=13.417,封面论文)
Yandong Zhan#, Youkui Huang#, Jingying Chen#, Zigang Cao, Jianbo He, Jingjing Zhang, Honghui Huang, Hua Ruan, Lingfei Luo*, Li L*. The caudal dorsal artery generates hematopoietic stem and progenitor cells via the endothelial-to-hematopoietic transition in zebrafish. Journal of Genetics and Genomics. 2018 Jun 8:S1673-8527(18)30099-7. (IF=5.723)
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