近期论文
查看导师最新文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
Aiyer, S., Baldwin, P. R., Tan, S. M., Shan, Z., Oh, J., Mehrani, A., Bowman, M. E., Louie, G., Passos, D. O., Đorđević-Marquardt, S., Mietzsch, M., Hull, J. A., Hoshika, S., Barad, B. A., Grotjahn, D. A., McKenna, R., Agbandje-McKenna, M., Benner, S. A., Noel, J. A. P., Wang, D., Tan, Y. Z., Lyumkis, D. (2024) Overcoming resolution attenuation during tilted cryo-EM data collection. Nat. Commun. 15, 389.
Saram, R. D., Xu, J., Lahiri, I., Gong, W., Li, Q., Oh, J., Zhou, Z., Hou, P., Chong, J., Hao, N., Li, S.*, Wang, D.*, Leschziner, A. E*. (2024) Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc . Natl. Acad. Sci. USA. 121 (3), e2314245121.
Oh, J., Shan, Z., Hoshika, S., Xu, J., Chong, J., Benner, S. A.*, Lyumkis, D.*, Wang, D.* (2023) A Unified Watson-Crick Geometry Drives Transcription of Six-Letter Expanded DNA Alphabets by E. coli RNA Polymerase. Nat. Commun. 14:8219.
Oh, J., Kimoto, M., Xu, H., Chong, J, Hirao, I*, Wang, D.* (2023) Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase. Nat. Commun. 14:195.
Unarta, I. C., Goonetilleke, E. C., Wang, D., Huang, X. H. (2023) Nucleotide Addition and Cleavage by RNA Polymerase II: Coordination of Two Catalytic Reactions using a Single Active Site. J. Biol. Chem. DOI: https://doi.org/10.1016/j.jbc.2022.102844
Yan, W., Cao, M., Ruan, X., Jiang, L., Lee, S., Lemanek, A., Ghassemian, M., Pizzo, D.P., Wan, Y., Qiao, Y., Chin, A.R., Duggan, E., Wang, D., Nolan, J.P., Esko, J.D., Schenk, S.* & Wang, S.E.* (2022) Cancer-cell-secreted miR-122 suppresses O-GlcNAcylation to promote skeletal muscle proteolysis. Nat. Cell Biol. 24, 793-804.
Fei, J., Xu, J., Li, Z., Xu, K., Wang, D., Kassavetis, G.A. & Kadonaga, J.T. (2022) NDF is a transcription factor that stimulates elongation by RNA polymerase II. Genes Dev. 36, 294-299.
Oh, J., Jia, T., Xu, J., Chong, J., Dervan, P.B.* & Wang, D.* (2022) RNA polymerase II trapped on a molecular treadmill: structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc. Natl. Acad. Sci. USA. 119 (3), e2114065119.
Yan, C., Dodd, T., Yu, J., Leung, B., Xu, J., Oh, J., Wang, D.* & Ivanov, I. * (2021) Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair. Nat. Commun. 12:7001.
Xu, J., Oh, J., Chong, J., Xu, L., & Wang, D.* (2021) Molecular Basis for Transcriptional Fidelity Control by RNA polymerase II. In R. Landick, J.D. Wang, & T. Strick (Eds) RNA Polymerases as Molecular Motors. 2nd Ed. Royal Society of Chemistry Press.
Xu, J., Chong, J. & Wang, D.* (2021) Strand-specific effect of Rad26 and TFIIS in rescuing transcriptional arrest by CAG trinucleotide repeat slip-outs. Nucleic Acids Res. doi: 10.1093/nar/gkab573.
Oh, J., Shin, J., Unarta, I.C., Wang, W., Feldman, A.W., Karadeema, R.J., Xu, L., Xu, J., Chong, J., Krishnamurthy, R., Huang, X., Romesberg, F.E. & Wang, D.* (2021) Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat. Chem. Biol. doi: 10.1038/s41589-021-00817-3.
Konovalov, K.A., Wang, W., Wang, G., Gao, X., Wang, D. & Huang, X.* (2021) A comprehensive mechanism for 5-carboxylcytosine-induced transcriptional pausing revealed by Markov state models. J. Biol. Chem. doi: 10.1016/j.jbc.2021.100735.
Xu, J., Chong, J. & Wang, D.* (2021) Opposite roles of transcription elongation factors Spt4/5 and Elf1 on RNA polymerase II transcription through B-form versus non-B DNA structures. Nucleic Acids Res. doi: 10.1093/nar/gkab240.
Yuan, S., Yin, X., Meng, X., Chan, J.F.-W., Ye, Z.-W., Riva, L., Pache, L., Chan, C.C.-Y., Lai, P.M., Chan, C..C.-S., Poon, V.K.-M., Lee, A.C.-Y., Matsunaga, N., Pu, Y., Yuen, C.-K., Cao, J., Liang, R., Tang, K., Sheng, L., Du, Y., Xu, W., Lau, C.-Y., Sit, K.-Y., Au, W.-K., Wang, R., Zhang, Y.-Y., Tang, Y.-D., Clausen, T.M., Pihl, J., Oh, J., Sze, K.-H., Zhang, A.J., Chu, H., Kok, K.-H., Wang, D., Cai, X.-H., Esko, J.D., Hung, I.F.-N., Li, R.A., Chen, H., Sun, H., Jin, D.-Y., Sun, R.*, Chanda, S.K.* & Yuen, K.Y.* (2021) Clofazimine broadly inhibits coronaviruses including SARS-CoV-2. Nature. doi: 10.1038/s41586-021-03431-4.
Milanovic, M., Shao, Z., Estes, V.M., Wang, X.S., Menolfi, D., Lin, X., Lee, B.J., Xu, J., Cupo, O.M., Wang, D. & Zha, S. (2021) FATC Domain Deletion Compromises ATM Protein Stability, Lymphocyte Development, and Promotes Lymphomagenesis. J. Immun. 206(6):1228-1239.
Oh, J., Xu, J.,, Chong, J. & Wang, D.* (2021) Molecular Basis of Transcriptional Pausing, Stalling, and Transcription-coupled Repair Initiation. Biochim. Biophys. Acta. Gene Regul. Mech. 1864(1):194659.
Milanovic, M., Sprinzen, L., Lee, J.H., Yamamoto, K., Li, Y., Lee, B.J., Xu, J., Estes, V.E., Wang, D., Mckinnon, P.J., Paull, T. & Zha, S. (2021) The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM activation and Its Exchange. Cancer Res. 81(2): 426-437.
Wang, D.* (2020) Using Genetics to Reveal Protein Structure. Science. 370(6522): 1269-1270.
Xu, J., Wang, W., Xu, L., Chen, J.Y., Chong, J., Oh, J., Leschziner, A.E., Fu, X.D. & Wang, D.* (2020) Cockayne Syndrome B Protein Acts as an ATP-Dependent Processivity Factor that Helps RNA Polymerase II Overcome Nucleosome Barriers. Proc. Natl. Acad. Sci. USA. doi: 10.1073/pnas.2013379117.
Wang, D.* (2020) A Panorama of Transcription-Coupled Repair in Yeast Chromatin. Proc. Natl. Acad. Sci. USA. doi:10.1073/pnas.2014392117.
Oh., J., Fleming, A.M., Xu, J., Chong, J., Burrows, C.J. & Wang, D.* (2020) RNA Polymerase II Stalls on Oxidative DNA Damage via a "Torsion-Latch" Mechanism Involving Lone Pair-Pi and CH-Pi Interactions. Proc. Natl. Acad. Sci. USA. 117(17): 9338-9348. PMCID: PMC7196775.
Di, L., Fu, Y., Sun, Y., Li, J., Liu, L., Yao, J., Wang, G., Wu, Y., Lao, K., Lee, R.W., Zheng, G., Xu, J., Oh, J., Wang, D., Xie, X.S., Huang, Y. & Wang J. (2020) RNA Sequencing by Direct Tagmentation of RNA/DNA Hybrids. Proc. Natl. Acad. Sci. USA. 117(6):2886-2893. PMCID: PMC7022195.