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个人简介

1963年11月出生,女,复旦大学特聘教授 1991.9-1996.7,美国哥伦比亚大学,遗传学博士 1996-1997,法国国际癌症研究机构 博士后 1997-1998,美国匹兹堡大学 助理教授 (研究系列) 1998-2004,美国约翰·霍普金斯·布隆伯格公共卫生学院 助理教授 2004-2007,美国约翰·霍普金斯·布隆伯格公共卫生学院 副教授 (终身) 2007-2016,美国国家精神卫生研究所遗传流行病学研究组负责人 2016-今,美国国家精神卫生研究所统计基因组学和数据分析中心主任 2017-今,复旦大学生命科学院特聘教授 获奖情况 2001年:约翰霍普金斯大学医学院“NIH Directors award” 2003年: 约翰霍普金斯大学公共卫生学院“The Louis I. and Thomas D. Dublin award” 2006年:约翰霍普金斯大学公共卫生学院 “The Helen Abbey Award for Advising, Mentoring and Teaching Recognition”

研究领域

长期从事统计遗传学、精神病遗传学和计算生物学的研究

近期论文

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(#并列一作,*通讯) Bing-Jian, F., Huang, W., Shugart, Y.Y. #, et al.2002. Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4.;Nature genetics,;31(4), p.395. Shugart, Y.Y. #, et al, 2006. Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q.;Molecular psychiatry,;11(8), p.763. Qin H, et al, Nestadt G, Shugart, Y.Y.*, 2016. Whole genome association analysis of treatment response in obsessive-compulsive disorder.;Molecular psychiatry,;21(2), p.270. Qin, H.D., Shugart, Y.Y. #, et al. and Zeng, Y.X., 2011. Comprehensive pathway-based association study of DNA repair gene variants and the risk of nasopharyngeal carcinoma.;Cancer research, pp.canres-0469. Shugart, Y.Y. #, 1998. Anticipation in familial Hodgkin lymphoma.;American journal of human genetics,;63(1), p.270. Qin, H.D., et al, Shugart, Y.Y.*, Jia WH*. 2016. Genomic characterization of esophageal squamous cell carcinoma reveals critical genes underlying tumorigenesis and poor prognosis.;The American Journal of Human Genetics,;98(4), pp.709-727. Xu, Y., Yue, W., Shugart, Y.Y. #, et al., 2015. Exploring transcription factors-microRNAs Co-regulation networks in schizophrenia.;Schizophrenia bulletin,;42(4), pp.1037-1045. Ritter, M.L., et al, Gerald Nestadt* and Shugart, Y.Y.* 2017. Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD).;Frontiers in molecular neuroscience,;10. Hong, S.E., Shugart, Y.Y., et al. and Walsh, C.A., 2000. Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations.;Nature genetics,;26(1), p.93. Willour, V.L., Shugart, Y.Y., et al., 2004. Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder.;The American Journal of Human Genetics,;75(3), pp.508-513. Ahn, K., An, S.S., Shugart, Y.Y. and Rapoport, J.L., 2016. Common polygenic variation and risk for childhood-onset schizophrenia.;Molecular psychiatry,;21(1), p.94. Cao, H., Duan, J., Lin, D., Shugart, Y.Y., Calhoun, V. and Wang, Y.P., 2014. Sparse representation based biomarker selection for schizophrenia with integrated analysis of fMRI and SNPs.;Neuroimage,;102, pp.220-228. Kiezun, A., Garimella, K., Do, R., Stitziel, N.O., Neale, B.M., McLaren, P.J., Gupta, N., Sklar, P., Sullivan, P.F., Moran, J.L. and Hultman, C.M., 2012. Exome sequencing and the genetic basis of complex traits.;Nature genetics,;44(6), pp.623-630.

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