个人简介
工作经历
2008.09 - 2012.06,武汉科技大学,药学,学士
2012.09 - 2019.01,复旦大学药学院,药物化学,博士
2019.01 - 2021.12,复旦大学生物医学研究院,生物学,博士后
2021.12 - 至今,复旦大学人类表型组研究院,青年副研究员
获奖情况
复旦大学“超级博士后”(2020)
国家自然科学基金青年项目(81903422)(2020)
上海市卫健委临床专项青年项目(20194Y0120)(2020)
博士后基金面上项目(2019M651384)(2019)
国家博士后创新人才支持计划“博新计划”(BX20180065) (2018)
上海市超级博士后激励计划“超博计划” (2018040) (2018)
研究领域
基于表型组大队列平台发现的自身免疫性疾病和肿瘤相关新靶点进行原创新药研发
基于活性天然产物的合成及其功能机制作用靶点和临床适应症的药物发现
近期论文
查看导师新发文章
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Mei-Lin Tang, Haidong Li, Jin-Feng Ning, Xiaoyan Shen*, and Xun Sun*. Discovery of First-in-Class TAK1–MKK3 Protein–Protein Interaction (PPI) Inhibitor (R)-STU104 for the Treatment of Ulcerative Colitis through Modulating TNF-α Production. J. Med. Chem. 2022, 65, 9, 6690–6709.
Mei-Lin Tang, Zi-Hao Wen, Jing-Huan Wang, Mei-Ling Wang, Heyanhao Zhang, Xin-Hua Liu, Lin Jin*, and Jun Chang*. Discovery of Pyridone-Substituted Triazolopyrimidine Dual A2A/A1 AR Antagonists for the Treatment of Ischemic Stroke. ACS Med. Chem. Lett. 2022, 13, 3, 436–442.
Mei-Lin Tang, Chen Zhong, Zheng-Yu Liu, Peng Peng, Xin-Hua Liu*, Xun Sun*. Discovery of novel sesquistilbene indanone analogues as potent anti-inflammatory agents. Eur. J. Med. Chem. 2016, 113, 63–74.
Mei-Lin Tang, Lu Zhou, Jun Chang, Zhuo-Han Hu, Yan Qin*, Xun Sun*. Differential metabolism of 3FDT and docetaxel in RLMs, rats, and HLMs. Eur. J. Med. Chem. 2016, 113, 81–91.
Mei-Lin Tang, Peng Peng, Zheng-Yu Liu, Jian Zhang, Jian-Ming Yu, Xun Sun*. Sulfoxide-Based Enantioselective Nazarov Cyclization: Divergent Syntheses of (+)-Isopaucifloral F, (+)-Quadrangularin A, and(+)-Pallidol. Chem. Eur. J. 2016, 22, 14535–14539.