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Tian-Yi Jiang, Yu-Fei Pan, Zheng-Hua Wan, Yun-Kai Lin, Bin Zhu, Zhen-gang Yuan,Yun-Han Ma, Yuan-Yuan Shi, Tian-Mei Zeng, Li-Wei Dong*, Ye-Xiong Tan& Hong-Yang Wang*. PTEN status determines the chemosensitivity to proteasome inhibition in cholangiocarcinoma. Science Translational Medicine 2020 [Epub ahead of print]
Xiaofang Zhao, Wenhao Qin, Youhai Jiang, Zhishi Yang, Bo Yuan, Rongyang Dai, Hao Shen, Yao Chen, Jing Fu*, Hongyang Wang*. ACADL plays a tumor-suppressor role by targeting Hippo/YAP signaling in hepatocellular carcinoma. npj Precision Oncology 2020 Mar 25;4:7.
Qin WH, Yang ZS, Li M, Chen Y, Zhao XF, Qin YY, Song JQ, Wang BB, Yuan B, Cui XL, Shen F, He J, Bi YF, Ning G*, Fu J*, Wang HY*.High Serum Levels of Cholesterol Increase Antitumor Functions of Nature Killer Cells and Reduce Growth of Liver Tumors in Mice. Gastroenterology. 2020 Jan 20. pii: S0016-5085(20)30118-9. doi: 10.1053/j.gastro.2020.01.028. [Epub ahead of print]
Cai J, Chen L, Zhang Z, Zhang X, Lu X, Liu W, Shi G, Ge Y, Gao P, Yang Y, Ke A, Xiao L, Dong R, Zhu Y, Yang X, Wang J, Zhu T, Yang D, Huang X, Sui C, Qiu S, Shen F, Sun H, Zhou W, Zhou J, Nie J, Zeng C, Stroup EK, Zhang X, Chiu BC, Lau WY, He C, Wang H, Zhang W, Fan J. Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma. Gut. 2019 Jul 29. [Epub ahead of print] (IF=17.1)
Wei Y, Chen X, Liang C, Ling Y, Yang X, Ye X, Zhang H, Yang P, Cui X, Ren Y, Xin X, Li H, Wang R, Wang W, Jiang F, Liu S, Ding J, Zhang B, Li L*, Wang H*.A Noncoding Regulatory RNAs Network Driven by Circ-CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma. Hepatology. 2020 Jan;71(1):130-147.(IF= 14.079)
Cheng Z, He Z, Cai Y, Zhang C, Fu G, Li H, Sun W, Liu C, Cui X, Ning B, Xiang D, Zhou T, Li X, Xie W*, Wang H*, Ding J*. Conversion of hepatoma cells to hepatocyte-like cells by defined hepatocyte nuclear factors. Cell Res. 2019 Feb;29(2):124-135. (IF=15.4 )
Liu J, Jiang J, Mo J, Liu D, Cao D,Wang H, He Y, Wang H*. Global DNA 5-hydroxymethylcytosine and 5-formylcytosine contents are decreased in the early stage of hepatocellular carcinoma. Hepatology. 2019 Jan;69(1):196-208(IF= 14.079)
Fu GB, Huang WJ, Zeng M, Zhou X, Wu HP, Liu CC, Wu H, Weng J, Zhang HD, Cai YC, Ashton C, Ding M, Tang D, Zhang BH, Gao Y, Yu WF, Zhai B, He ZY, Wang HY*, Yan HX*. Expansion and differentiation of human hepatocyte-derived liver progenitor-like cells and their use for the study of hepatotropic pathogens. Cell Res. 2019 Jan;29(1):8-22(IF=15.4 )
Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W*, Wang H*.Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer. Nat Commun. 2018 Jan 15;9(1):191. (IF=12.353)
Wang B, Fu J, Yu T, Xu A, Qin W, Yang Z, Chen Y*, Wang H*. Contradictory Effects of Mitochondria- and Non-mitochondria-targeted Antioxidants on Hepatocarcinogenesis by Altering DNA Repair. Hepatology 2017 Sep 12. doi: 10.1002/hep.29518. (IF=11.711)
Xi-Meng Lin, Liang Hu, Jin Gu, Ruo-Yu Wang, Liang Li, Jing Tang, Bao-Hua Zhang, Xing-Zhou Yan, Yan-Jing Zhu, Cong-Li Hu, Wei-Ping Zhou, Frank J Gonzalez, Meng-Chao Wu, Hong-Yang Wang*, and Lei Chen*.Choline Kinase Alpha-Driven Assembly of EGFR and mTORC2 Promotes Hepatocellular Carcinoma Metastasis and Drug Resistance. Gastroenterology 2017 Apr 1, 152:1187-1202(IF=18.187)
Yang Y, Chen L, Gu J, Zhang H, Yuan J, Lian Q, Lv G, Wang S, Wu Y, Yang YT, Wang D, Liu Y, Tang J, Luo G, Li Y, Hu L, Sun X, Wang D, Guo M, Xi Q, Xi J, Wang H, Zhang MQ, Lu ZJ*. Recurrently deregulated lncRNAs in hepatocellular carcinoma. Nat Commun. 2017 Feb 13;8:14421. doi: 10.1038/ncomms14421(IF=11.47)
Wu H, Zhou X, Fu GB, He ZY, Wu HP, You P, Ashton C, Wang X, Wang HY*, Yan HX*. Reversible transition between hepatocytes and liver progenitors for in vitro hepatocyte expansion. Cell Res. 2017 May;27(5):709-712(IF=15.606)
Ke S, Chen S, Dong Z, Hong CS, Zhang Q, Tang L, Yang P, Zhai J, Yan H, Shen F, Zhuang Z, Wen W*, Wang H*.Erythrocytosis in hepatocellular carcinoma portends poor prognosis by respiratory dysfunction secondary to mitochondrial DNA mutations. Hepatology. 2017 Jan;65(1):134-151(IF=11.711)
Hou G, Chen L, Liu G, Li L, Yang Y, Yan HX, Zhang HL, Tang J, Yang YC, Lin X, Chen X, Luo GJ, Zhu Y, Tang S, Zhang J, Liu H, Gu Q, Zhao LH, Li Y, Liu L*, Zhou W*, Wang H*. Aldehyde Dehydrogenase-2 (ALDH2) Opposes HCC Progression By Regulating AMPK Signaling. Hepatology. 2017 May;65(5):1628-1644(IF=11.055)
Yun-Han Ma, Wei-Tao Dou, Yu-Fei Pan, Li-Wei Dong, Ye-Xiong Tan, Xiao-Peng He,* He Tian, and Hong-Yang Wang* . Fluorogenic 2D Peptidosheet Unravels CD47 as a Potential Biomarker for Profiling Hepatocellular Carcinoma and Cholangiocarcinoma Tissues. Adv Mater. 2017 Feb;29(5). doi: 10.1002/adma.201604253. Epub 2016 Nov 21. (IF=18.96)
Qu L, Ding J, Chen C, Wu ZJ, Liu B, Gao Y, Chen W, Liu F, Sun W, Li XF, Wang X, Wang Y, Xu ZY, Gao L, Yang Q, Xu B, Li YM, Fang ZY, Xu ZP, Bao Y, Wu DS, Miao X, Sun HY, Sun YH, Wang HY*, Wang LH*. Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA. Cancer Cell. 2016 May 9;29(5):653-68 (IF= 23.214)
Ling-Hao Zhao, Xiao Liu, He-Xin Yan, Wei-Yang Li, Xi Zeng, Yuan Yang, Jie Zhao,Shi-Ping Liu, Xue-Han Zhuang, Chuan Lin, Chen-Jie Qin, Yi Zhao, Ze-Ya Pan, Gang Huang, Hui Liu,Jin Zhang, Ruo-Yu Wang, Yun Yang, Wen Wen, Gui-Shuai Lv, Hui-Lu Zhang, Han Wu, Shuai Huang,Ming-Da Wang, Liang Tang, Hong-Zhi Cao, Ling Wang, Tin-Lap Lee, Hui Jiang, Ye-Xiong Tan,Sheng-Xian Yuan, Guo-Jun Hou, Qi-Fei Tao, Qin-Guo Xu, Xiu-Qing Zhang, Meng-Chao Wu, Xun Xu,Jun Wang, Huan-Ming Yang, Wei-Ping Zhou & Hong-Yang Wang* . Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun. 2016 Oct 5;7:12992(IF=11.47)
Yang C, Tan YX, Yang GZ, Zhang J, Pan YF, Liu C, Fu J, Chen Y, Ding ZW, Dong LW, Wang HY*. Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma.J Exp Med. 2016 May 2;213(5):859-75. doi: 10.1084/jem.20151208. Epub 2016 Apr 18 (IF= 11.24)
Yang Y, Lin X, Lu X, Luo G, Zeng T, Tang J, Jiang F, Li L, Cui X, Huang W, Hou G, Chen X, Ouyang Q, Tang S, Sun H, Chen L, Gonzalez FJ, Wu M, Cong W, Chen L*, Wang H*. Interferon-microRNA signalling drives liver precancerous lesion formation and hepatocarcinogenesis. Gut. 2016 Jul;65(7):1186-201 (IF=14.921)