陈丰荣 - 复旦大学 - 代谢与整合生物学研究院

个人简介

2004年6月在台湾交通大学电子物理学系获工学学士学位；2012年9月在台湾交通大学光电工程学院获工学博士学位；2013年10月至2018年6月，在清华大学生命科学学院从事博士后研究（合作导师：李蓬院士/教授）；2018年7月被聘为复旦大学代谢与整合生物学研究院青年研究员。荣誉及获奖情况 2016年脂代谢与生物能量会议杰出海报奖 2015年冷泉港亚洲会议最佳海报奖 2013年清华-北大生命科学联合中心博士后基金 2013年斐陶斐荣誉学会荣誉会员

研究领域

从事脂代谢相关的脂滴定量生物学与脂质储存可塑性调控的分子机制，结合生物物理学建模手段、人工智能方法与传统分子、生化学方法，以交叉学科思维来阐明细胞内脂质生理代谢或病理紊乱的发生发展机制。

近期论文

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Kevin Qian, Marcus J. Tol, Jin Wu, Lauren F. Uchiyama, Xu Xiao, Liujuan Cui, Alexander H. Bedard, Thomas A. Weston, Pradeep S. Rajendran, Laurent Vergnes, Yuta Shimanaka, Yesheng Yin, Yasaman Jami-Alahmadi, Whitaker Cohn, Bryce T. Bajar, Chia-Ho Lin, Benita Jin, Laura A. DeNardo, Douglas L. Black, Julian P. Whitelegge, James A. Wohlschlegel, Karen Reue, Kalyanam Shivkumar, Feng-Jung Chen, Stephen G. Young, Peng Li, and Peter Tontonoz. CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization. Nature, 2023, 613:160-168. Guoqing Tang†, Chengxin Ma†, Liangkui Li, Shaoyan Zhang, Fengsheng Li, Jin Wu, Yesheng Yin, Qing Zhu, Yan Liang, Ru Wang, He Huang, Tong-Jin Zhao, Hongyuan Yang, Peng Li, and Feng-Jung Chen. PITPNC1 promotes the thermogenesis of brown adipose tissue under acute cold exposure. SCIENCE CHINA-Life Sciences, 2022,65:2287-2300. (†Co-first authors) Xuchao Lyu†, Jia Wang†, Jianqin Wang†, Ye-Sheng Yin, Yun Zhu, Lin-Lin Li, Shuangru Huang, Shuang Peng, Boxin Xue, Rongyu Liao, Shi-Qiang Wang, Mian Long, Thorsten Wohland, Boon Tin Chua, Yujie Sun, Pilong Li, Xiao-Wei Chen, Li Xu, Feng-Jung Chen*, and Peng Li*. A gel-like condensation of Cidec generates lipid-permeable plates for lipid droplet fusion. Developmental Cell, 2021, 56:2592-2606. (†Co-first authors; *Co-corresponding authors) Feng-Jung Chen, Yesheng Yin, Boon Tin Chua, and Peng Li. CIDE family proteins control lipid homeostasis and the development of metabolic diseases. Traffic, 2020, 21(1): 94-105. (Invited review article) Jia Wang, Boon Tin Chua, Peng Li, and Feng-Jung Chen. Lipid-exchange rate assay for lipid droplet fusion in live cells. Bio-protocol, 2019, 9: e3309. Jia Wang, Chengsong Yan, Chenqi Xu, Boon Tin Chua, Peng Li*, and Feng-Jung Chen*. Polybasic RKKR motif in the linker region of lipid droplet (LD)-associated protein CIDEC inhibits LD fusion activity by interacting with acidic phospholipids. The Journal of. Biological Chemistry, 2018, 293(50): 19330–19343. (*Co-corresponding authors) Feng-Jung Chen, Jhih-Sian Wong, Ken Y. Hsu, and Long Hsu. Thermally activated state transition technique for femto-Newton-level force measurement. Optics Letters, 2012, 37(9): 1469–1471. Chia-Han Chan†, Feng-Jung Chen†, Ying-Jung Huang, Hsin-Yu Chen, Kuo-Liang Liu, Zhe-Chong Wang, Hwei-Ling Peng, Tri-Rung Yew, Cheng-Hsien Liu, Gunn-Guang Liou, Ken Y. Hsu, Hwan-You Chang, and Long Hsu. Identification of protein domains affecting mechanical properties of Klebsiella pneumoniae type 3 fimbriae. Langmuir, 2012, 28(19): 7428–7435. (†Co-first authors) Feng-Jung Chen†, Chia-Han Chan†, Ying-Jung Huang, Kuo-Liang Liu, Hwei-Ling Peng, Hwan-You Chang, Gunn-Guang Liou, Tri-Rung Yew, Cheng-Hsien Liu, Ken Y. Hsu, and Long Hsu. Structural and mechanical properties of Klebsiella pneumonia type 3 fimbriae. Journal of Bacteriology, 2011, 193(7): 1718–1725. (†Co-first authors)