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Guo H#, Wang J#, Ren S#, Zheng LF#, Zhuang YX, Li DL, Sun HH, Liu LY, Xie C, Wu YY, Wang HR, Deng X, Li P, Zhao TJ* (2022). Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system. Nature Communications, 13:6004
Wang J, Liang G*, Zhao TJ*. (2022) Adipose triglyceride lipase: The first transacylase for FAHFAs. Life Metabolism, Epub ahead
Hao JW#, Wang J#, Guo H#, Zhao YY, Sun HH, Li YF, Lai XY, Zhao N, Wang X, Xie C, Hong L, Huang X, Wang HR, Li CB, Liang B, Chen S*, Zhao TJ*. (2020) CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis. Nat Commun.11:4765
Wang J#, Hao JW#, Wang X#, Guo H#, Sun HH, Lai XY, Liu LY, Zhu M, Wang HY, Li YF, Yu LY, Xie C, Wang HR, Mo W, Zhou HM, Chen S, Liang G, Zhao TJ*. (2019) DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane. Cell Rep.26:209-221
Wen-Shuai Tang#, Li Weng#, Xu Wang#, Chang-Qin Liu#, Guo-Sheng Hu, Shu-Ting Yin, Ying Tao, Ni-Na Hong, Huiling Guo, Wen Liu, Hong-Rui Wang, Tong-Jin Zhao*. The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesity. Cell Reports, 2021, 36(1): 109314.
Xu Wang#, Hao-Yan Wang#, Guo-Sheng Hu#, Wen-Shuai Tang, Li Weng, Yuzhu Zhang, Huiling Guo, Shan-Shan Yao, Shen-Ying Liu, Guo-Liang Zhang, Yan Han, Min Liu, Xiao-Dong Zhang, Xiang Cen, Hai-Feng Shen, Nengming Xiao, Chang-Qin Liu, Hong-Rui Wang, Jing Huang, Wen Liu, Peng Li, Tong-Jin Zhao*. DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity. Cell Reports, 2021, 35(12): 109281.
Jian-Wei Hao#, Juan Wang#, Huiling Guo#, Yin-Yue Zhao, Hui-Hui Sun, Yi-Fan Li, Xiao-Ying Lai, Ning Zhao, Xu Wang, Changchuan Xie, Lixin Hong, Xi Huang, Hong-Rui Wang, Cheng-Bin Li, Bin Liang, Shuai Chen*, Tong-Jin Zhao*. CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis. Nat Commun, 2020, 11: 4765.
Ou Z#, Ma Y#, Sun Y#, Zheng G, Wang S, Xing R, Chen X, Han Y, Wang J, Lu QR*, Zhao TJ*, Chen Y*. A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism. Cell Rep, 2019, 26: 2984-2997.
Wang J#, Hao JW#, Wang X#, Guo H#, Sun HH, Lai XY, Liu LY, Zhu M, Wang HY, Li YF, Yu LY, Xie C, Wang HR, Mo W, Zhou HM, Chen S, Liang G, Zhao TJ*. DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane. Cell Rep, 2019, 26: 209-221.
Liu M#, Zeng T#, Zhang X#, Liu C, Wu Z, Yao L, Xie C, Xia H, Lin Q, Xie L, Zhou D, Deng X, Chan HL, Zhao TJ*, Wang HR*. ATR/Chk1 signaling induces autophagy through sumoylated RhoB-mediated lysosomal translocation of TSC2 after DNA damage. Nat Commun, 2018, 9: 4139.
Zhang Y, Fang F, Goldstein JL*, Brown MS*, Zhao TJ. Reduced autophagy in livers of fasted, fat-depleted ghrelin-dificient mice: reversal by growth hormone. Proc Natl Acad Sci USA, 2015,112: 1226-1231.
McFarlane MR, Brown MS*, Goldstein JL*, Zhao TJ. Induced Ablation of Ghrelin Cells in Adult Mice Does Not Decrease Food Intake, Body Weight, or Response to High-Fat Diet. Cell Metab, 2014, 20: 54-60.
Li RL#, Sherbet DP#, Elsbernd BL, Goldstein JL*, Brown MS*, Zhao TJ. Profound hypoglycemia in starved, ghrelin-deficient mice is caused by decreased gluconeogenesis and reversed by lactate or fatty acids. J Biol Chem, 2012, 287: 17942-17950.
Zhao TJ#, Sakata I#, Li RL, Liang G, Richardson JA, Brown MS*, Goldstein JL*, Zigman JM*. Ghrelin secretion stimulated by β1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice. Proc Natl Acad Sci U S A, 2010, 107: 15868-15873. (From the cover)
Zhao TJ#, Liang G#, Li RL, Xie X, Sleeman MW, Murphy AJ, Valenzuela DM, Yancopoulos GD, Goldstein JL*, Brown MS*. Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice. Proc Natl Acad Sci U S A, 2010, 107: 7467-7472. (From the cover)
Yang J#, Zhao TJ#, Goldstein JL*, Brown MS*. (2008) Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides. Proc Natl Acad Sci U S A, 2008, 105: 10750-10755. (Co-first author)
Qi J#, Gong J#, Zhao TJ#, Zhao J, Lam P, Ye J, Li JZ, Wu J, Zhou HM*, Li P*. Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue. EMBO J, 2008, 27: 1537-1548. (Co-first author)
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