个人简介

Biemann Medal (American Society for Mass Spectrometry), 2009 Pittsburgh Conference Achievement Award (American Chemical Society, DAC), 2008 Pfizer Award in Enzyme Chemistry (American Chemical Society, DBC), 2006 A.F. Findeis Award in Measurement Science (American Chemical Society, DAC), 2006 Presidential Early Career Award in Science and Engineering, 2005 Camille Dreyfus Teacher-Scholar Award, 2004 Sloan Fellow, 2003 Packard Fellowship, 2002-2007 Cottrell Scholars Award, 2002 National Science Foundation CAREER Award, 2002-2007 Research Corporation Innovation Award, 2001 Burroughs Wellcome Award in the Pharmacological Sciences, 2000-2003 Searle Scholar Award, 2000-2003 NIH (NIAID) K22 Career Transition Award, 2000-2002 American Society of Mass Spectrometry Research Award, 2000 Henry Dreyfus New Faculty Award, 1999-2000

研究领域

Organic, Chemical Biology, Physical, Analytical, Bio-analytical

Chemical Biology

近期论文

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Durbin, K.R., Tran, J.C., Zamdborg, L., Sweet, S.M., Catherman, A.D., Lee, J.E., Li, M., Kellie, J.K., Kelleher, N.L. “Intact Mass Detection, Interpretation, and Visualization to Automate Top-Down Proteomics on a Large Scale” Proteomics [Epub ahead of print]. Kellie, J.F., Tran J.C., Lee, J.E., Ahlf, D.R., Thomas, H.M., Ntai, I., Catherman, A.D., Durbin, K.R., Zamdborg, L., Vellaichamy, A., Thomas, P.M., Kelleher, N.L. “The Emerging Process of Top Down Mass Spectrometry for Protein Analysis: Biomarkers, Protein-Therapeutics, and Achieving High Throughput” Mol. Biosyst., 2010, 6, 1532-1539. Sweet, S.M., Li, M., Thomas, P.M., Durbin, K.R., Kelleher, N.L. “Kinetics of Re-establising H3 K79 Methylation Marks in Global Human Chromatin” J. Biol. Chem., 2010, epub ahead of print. Evans, B.S., Robinson, S.J., Kelleher, N.L. “Surveys of Non-Robosomal Peptide and Polyketide Assembly Lines in Fungi and Prospects for Their Analysis in vitro and in vivo” Fungal Genet. Biol., 2010, epub ahead of print. Zheng, Y., John S., Pesavento, J.J., Schultz-Norton, J.R., Schiltz, R.L., Baek, S., Nardulli, A.M., Hager, G.L., Kelleher, N.L., Mizzen, C.A. “Histone H1 Phosphorylation is Associated with Transcription by RNA Polymerase I and II” J. Cell Biol., 2010, 189, 407-415. Romanova, E.V., Lee, J.E., Kelleher, N.L., Sweedler, J.V., Gulley, J.M. “Mass Spectrometry Screening Reveals Peptides Modulated Differentially in the Medial Prefrontal Cortex of Rats with Disparate Initial Sensitivity to Cocaine” AAPS Journal, 2010, 12, 443-454. Johannes, T.W., Desieno, M.A., Griffin, B.M., Thomas, P.M., Kelleher, N.L., Metcalf, W.W., Zhao, H. “Deciphering the Late Biosynthetic Steps of Antimalarial Compound FR-900098” Chem. Biol., 2010, 17, 57-64. Vellaichamy, A., Tran, J.C., Catherman, A.D., Lee, J.E., Kellie, J.F., Sweet, S.M., Zamdborg, L., Thomas, P.M., Ahlf, D.R., Durbin, K.R., Valaskovic, G.A., Kelleher, N.L. “Size-Sorting Combined with Improved Nanocapillary Liquid Chromatography-Mass Spectrometry for Identification of Intact Proteins up to 80 kDa” Anal. Chem., 2010, 82, 1234-1244. Lee, J.E., Atkins, N. Jr., Hatcher, N.G., Zamdborg, L., Gillette, M.U., Sweedler, J.V., Kelleher, N.L. “Endogenous Peptide Discovery of the Rat Circadian Clock: A Focused Study of the Suprachiasmatic Nucleus by Ultrahigh Performance Tandem Mass Spectrometry” Mol. Cell. Proteomics, 2010, 9, 285-297. Li, M., Jiang L., Kelleher, N.L. “Global Histone Profiling by LC–FTMS After Inhibition and Knockdown of Deacetylases in Human Cells” J. Chrom. B., 2009, 877, 3885-3892.