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个人简介

在脑保护研究中,首次发现并报道高压氧、吸入麻醉药、针刺麻醉等可模拟缺血预处理效果,诱导显著神经保护作用,并实现部分临床转化。提出了中国麻醉学发展方向应为围术期医学,以第一完成人获得国家科技进步一等奖、陕西省科学技术一等奖3项等奖项。获973、国家科技重大专项基金、国家自然科学基金重点基金、杰出青年基金等23项基金,发表SCI论著279篇(附代表性论文)。 在研科研项目 国家自然科学基金委员会,重大项目,82293640,围术期老年脑功能稳态维持的精准麻醉策略,1500万元,2023.01-2027.12,主持 国家自然科学基金委员会,重点项目,82293643,麻醉影响老年脑的特征性脑电及生物标记物预警体系的研究,450万元,2023.01-2027.12,主持 国家自然科学基金重点项目,82130121,髓样分化因子2在针刺镇痛整合效应中的作用机制,2022.1-2026.12 , 290万 ,在研,主持 科技创新2030-“脑科学与类脑研究”重大项目-子课题,情绪情感调控注意和记忆的神经环路机制,2021.01-2026.12,200万,在研,主持 国家自然科学基金重点项目,81730032,MD2在POCD形成中的双重作用机制及转化研究,2018.01-2022.12,300万元,在研,主持

研究领域

围术期脑功能保护 人工智能在麻醉与围术期医学中的转化

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Lu Z, Zheng H, Chen Z, Xu S, Chen S, Mi W, Wang T, Chai X, Guo Q, Zhou H, Yu Y, Zheng X, Zhang J, Ai Y, Yu B, Bao H, Zheng H, Huang W, Wu A, Deng X, Ma H, Ma W, Tao L, Yang X, Zhang J, Liu T, Ma HP, Liang W, Wang X, Zhang Y, Du W, Ma T, Xie Y, Xie Y, Li N, Yang Y, Zheng T, Zhang C, Zhao Y, Dong R, Zhang C, Zhang G, Liu K, Wu Y, Fan X, Tan W, Li N, Dong H*, Xiong L*. Effect of Etomidate vs Propofol for Total Intravenous Anesthesia on Major Postoperative Complications in Older Patients: A Randomized Clinical Trial.JAMA Surg. 2022;e223338. (IF:18.681) Zongping Fang#, Di Wu#, Jiao Deng#, Qianzi Yang,Xijing Zhang,Jian Chen,Shiquan Wang,Sijun Hu,Wugang Hou,Siming Ning,Yi Ding,Zhongmin Fan,Zhenhua Jiang,Junjun Kang,Yingying Liu,Jinlin Miao,Xunming Ji*, Hailong Dong*, Lize Xiong*. An MD2-perturbing peptide has therapeutic effects in rodent and rhesus monkey models of stroke. Sci Transl Med. 2021 Jun; 13(597):eabb6716. doi: 10.1126/scitranslmed.abb6716.(IF:19.319) Junyao Zhang#, Qianqian Shi, Ruizhi Wang, Xuan Zhang, Li Li, Jianhua Zhang, Li Tian*, Lize Xiong*, Jia Huang*. Spectrum-dependent photonic synapses based on 2D imine polymers for power-efficient neuromorphic computing. InfoMat. 2021 May 3(8). DOI:10.1002/inf2.12198.(IF:24.798) Lu Z#*, Wang Q, Sun X, Zhang W, Min S, Zhang J, Zhao W, Jiang J, Wang Y, Zhu Y, Zheng L, Wang Y, Guo Y, Zhang L, Wang L, Lei C, Liu T, Yang X, Zhang J, Li C, Zhang N, Dong H, Xiong L*.Transcutaneous electrical acupoint stimulation before surgery reduces chronic pain after mastectomy: A randomized clinical trial. J Clin Anesth. 2021 Jul 13(74):110453.2021.110453.(IF:9.375) Liu L #*, Li J #, Zuo L, Zhang J, Zhou M, Xu B, Hahn R, Leon M, His D, Ge J, Zhou X, Zhang J, Ge S, Xiong L*. Safety and Efficacy of Percutaneous Intra-myocardial Septal Radiofrequency Ablation for Hypertrophic Obstructive Cardiomyopathy. J Am Coll Cardiol. 2018 Oct 16;72(16):1898-1909. (IF=18.639) Lei C #, Berra L #, Rezoagli E, Yu B, Dong H, Yu S, Hou L, Chen M, Chen W, Wang H, Zheng Q, Shen J, Jin Z, Chen T, Zhao R, Zhao, Christie E, Sabbisetti V, Nordio F, Bonventre J, Xiong L*, Zapol W*. Nitric Oxide Decreases Acute Kidney Injury and Stage 3 Chronic Kidney Disease after Cardiac Surgery. Am J Respir Crit Care Med. 2018 Nov 15;198(10):1279-1287. (IF=16.494) Li Y#*, Yin A#, Sun X#, Zhang M#, Zhang J, Wang P, Xie R, Li W, Fan Z, Zhu Y, Wang H, Dong H, Wu S, Xiong L*.Deficiency of tumor suppressor NDRG2 leads to attention deficit and hyperactive behavior. J Clin Invest. 2017 Oct 23. pii: 94455. (IF=13.251) Zhong H#, Tong L#, Gu N#, Gao F#, Lu Y, Xie R, Liu J, Li X, Bergeron R, Pomeranz L, Mackie K, Wang F, Luo C, Ren Y, Wu S, Xie Z, Xu L, Li J, Dong H*, Xiong L*, Zhang X*. Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice. J Clin Invest. 2017 Jun 1;127(6):2295-2309 (IF=13.251)

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