杨浩 - 同济大学

个人简介

上海交通大学麻醉学博士、同济大学博士后，主要从事干细胞对炎症微环境的调控和围手术期肺损伤发生机制及相关保护策略的基础与临床转化研究，先后主持国家自然科学基金、中国博士后科学基金、上海市医学会麻醉学分会基础科研项目等课题 6 项，入选中国科协“青年人才托举”工程（麻醉学领域首位）及上海市医学会麻醉学分会“优秀青年医师海外研修”项目，参与国家科技部“973”计划项目、国家自然科学基金重点项目、面上项目等课题 9项。目前已发表 SCI 论文 30 余篇，其中以第一作者/通讯作者（含共同）发表 SCI 论文 20篇，中文核心期刊论文 6 篇，获授权专利 3 项，参编专著 4 部。研究成果受邀在美国麻醉医师协会年会及世界麻醉医师联合会年会上进行学术交流 3 次，并先后获得中华医学会麻醉学分会青年委员会优秀论文大赛二等奖、东方麻醉与围术期医学大会基础科研竞赛二等奖、东方麻醉与围术期医学大会优秀青年医师竞赛一等奖等奖项，协助培养同济大学、上海交通大学、南昌大学博士/硕士研究生 20 余人。申请人还担任 Thorax、Journal of Clinical Anesthesia、Critical Care、Oxidative Medicine and Cellular Longevity、Cell Proliferation、Frontiers in Cardiovascular Medicine 等 10 余家 SCI 期刊及临床麻醉学、中华危重病急救医学等多家国内核心期刊的审稿专家、客座主编等。

研究领域

急性肺损伤发病机制研究及肺保护措施研发、胸科手术麻醉的基础及临床研究

近期论文

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Yiguo Zhang#, Li Zheng#, Huimin Deng#, Di Feng, Song Hu, Lina Zhu, Wenting Xu, Wenyu Zhou, Yu Wang, Keting Min, Qing Zhou, Yuanli Chen, Huanping Zhou, Hao Yang*，Xin Lv*. Electroacupuncture Alleviates LPS-Induced ARDS Through a7 Nicotinic Acetylcholine Receptor-Mediated Inhibition of Ferroptosis. Frontiers in Immunology 2022. Wang Yu#, Wei Juan#, Deng Huimin, Zheng Li, Yang Hao*, Lv Xin*. The Role of Nrf2 in Pulmonary Fibrosis: Molecular Mechanisms and Treatment Approaches. Antioxidants 2022 Aug 29;11(9):1685. Huimin Deng#, Lina Zhu#, Yiguo Zhang#, Li Zheng, Song Hu, Wenyu Zhou, Tong Zhang, Wenting Xu, Yuanli Chen, Huanping Zhou, Quanfu Li, Juan Wei, Hao Yang*, Xin Lv*. Differential lung protective capacity of exosomes derived from human adipose tissue, bone marrow, and umbilical cord mesenchymal stem cells in sepsis-induced acute lung injury. Oxidative Medicine and Cellular Longevity 2022. Yuxin Du#, Yun Cai#, Yan Lv#, Lishen Zhang, Hao Yang, Quanzhong Liu, Ming Hong, Yue Teng, Weiyan Tang, Rong Ma, Jianqiu Wu, Jianzhong Wu, Qianghu Wang, Hongshan Chen*, Kening Li*, Jifeng Feng*. Single-cell RNA sequencing unveils the communications between malignant T and myeloid cells contributing to tumor growth and immunosuppression in cutaneous T-cell lymphoma. Cancer Letters. 2022 Oct 17;551:215972. Mingxia Wang#, Jinyuan Zhang#, Li Zheng#, Hongwei Fang, Yiguo Zhang, Huimin Deng, Mansi Wang, Xiuqin Yu, Qingxiang Meng, Yuanli Chen, Lijun Liao, Xin Lv, Hao Yang*, Xiangrui Wang*. Ultrasound-Guided Continuous Thoracic Paravertebral Infusion of Methylene Blue in the Treatment of Postherpetic Neuralgia: A Prospective, Randomized, Controlled Study. Pain and Therapy 2021 Apr 11. Wenting Xu#, Huimin Deng#, Song Hu#, Yiguo Zhang, Li Zheng, Meiyun Liu, Yuanli Chen, Juan Wei, Hao Yang*, Xin Lv*. Role of Ferroptosis in Lung Diseases. Journal of Inflammation Research 2021. Deng Huimin#, Wu Lingmin#, Liu Meiyun, Zhu Lina, Chen Yuanli, Zhou Huanping, Shi Xuan, Wei Juan, Zheng Li, Hu Xiaoting, Wang Mansi, He Zhengyu, Lv Xin*, Yang Hao*. Bone marrow mesenchymal stem cell-derived exosomes attenuate LPS-induced ARDS by modulating macrophage polarization through inhibiting glycolysis in macrophages. Shock 2020 12;54(6). Yang Hao#, Wu Lingmin#, Deng Huimin, Chen Yuanli, Zhou Huanping, Liu Meiyun, Wang Shaochen, Zheng Li, Zhu Lina*, Lv Xin*. Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling pathway in spinal microglia. Journal of Neuroinflammation 2020 May 11;17(1). Meiyun Liu, Yuanli Chen, Suyu Wang, Huanping Zhou, Di Feng, Juan Wei, Xuan Shi, Lingmin Wu, Pengcheng Zhang, Hao Yang*, Xin Lv*, α-ketoglutarate modulates macrophage polarization through regulation of PPARγ transcription and mTORC1/p70S6K pathway to ameliorate ALI/ARDS，Shock 2020 01;53(1). Hao Yang#，Tian-wei Tian，Shao-cheng Wang, Xiao-hua Liu, Zhan-kui Wang, Lei Hou，Jia-xi Ge, Xiao Zhang, Zhengyu He*, Xiang-rui Wang*, TSG-6 secreted by bone marrow mesenchymal stem cells attenuates intervertebral disc degeneration by inhibiting the TLR2/NF-κB signaling pathway, Laboratory Investigation. 2018 Jun;98(6):755-772.