个人简介
先后主持国家自然基金和上海市自然基金等课题,科研经费累计200余万元,在相关领域发表SCI论文15篇,其中以第一作者或通讯作者在Signal Transduction Targeted Therpy、Nature communications等杂志上发表6篇论文。
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Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer. Sig Transduct Target Ther 6, 398 (2021).
Fusobacterium Nucleatum Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 Signaling, Cancer Res, 81 (2021) 4485-4498.
A newly developed PCR-based method revealed distinct Fusobacterium nucleatum subspecies infection patterns in colorectal cancer, Microb Biotechnol, 14 (2021) 2176-2186.
Integrin alpha5 subunit is required for the tumor supportive role of fibroblasts in colorectal adenocarcinoma and serves as a potential stroma prognostic marker, Mol Oncol, 13 (2019) 2697-2714.
VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2. Nature communications 8 (2017), 15337.
Mitochondrial aldehyde dehydrogenase 2 protects gastric mucosa cells against DNA damage caused by oxidative stress. Free Radic Biol Med 93(2016) 165-176.