徐宏彬 - 同济大学

个人简介

同济大学附属第十人民医院药学部主任助理、崇明分院药剂科主任。上海市医学会儿科分会临床药学组组员。Plant Medica, BMJ Open, 《同济大学学报（医学版）》，《中国医院药学杂志》，《中国临床药学杂志》，《世界临床药物》编委。长期从事抗肿瘤药物药理（主要研究方向：中西药联用的抗肿瘤机制）和临床药理（主要研究方向：药物临床疗效和安全性）研究工作；近5年来，作为项目负责人获国家自然科学基金面上项目2项、上海市自然基金面上项目1项、崇明区科委科研课题1项，和上海市医院药学科研基金2项；在Clin Microb Infect、Int J Antimicrob Ag等杂志以第一作者和通讯作者发表SCI收录文章20篇；培养硕士研究生3名。

研究领域

抗肿瘤药物药理（主要方向：中西药联用的抗肿瘤机制）、临床药理（主要方向：药物临床疗效和安全性）

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Xu HB, Jiang RH, Xiao HP. Clofazimine in the treatment of multidrug-resistant tuberculosis. Clin Microb Infect 2012; 18: 1104-1110. IF: 4.578 Xu HB, Jiang RH, Li L, Xiao HP. Linezolid in the treatment of MDR-TB: a retrospective clinical study. Int J Tuberc Lung Dis 2012; 16: 358-363. IF: 2.61 Xu HB, Li L, Fu J, Mao XP, Xu LZ. Reversion of Multidrug Resistance in a Chemoresistant Human Breast Cancer Cell Line by β-Elemene. Pharmacology 2012; 89:303-312. IF: 1.603 Xu HB, Chen XZ, Jiang RH, Li L. Chinese herbal medicine in treatment of diabetic peripheral neuropathy: a systematic review and meta-analysis. J enthopharmacol 2012; 143:701-708. IF: 2.755 Xu HB, Xu LZ, Li L, Fu J, Mao XP. Reversion of P-glycoprotein-mediated multidrug resistance by guggulsterone in multidrug-resistant human cancer cell lines. Eur J Pharmacol 2012; 694:39-44. IF: 2.592 Liao Y, Zhong MK, Xu HB ( 通讯作者), Li L. Development and validation of a risk score for predicting invasive fungal infectious in an intensive care unit. Pharmazie 2013; 68: 459-464. IF: 1.003 Xu HB, Zheng LP, Li L, Xu LZ, Fu J. Elemene, one ingredient of a Chinese herb, against malignant tumors: a literature-based meta-analysis. Cancer Invest 2013; 31(2): 156-166. IF: 2.06 Chen XZ, Xu HB ( 通讯作者), Xu LZ, Mao XP, Li L. Guggulsterone regulates the function and expression of P-glycoprotein in rat brain microvessel endothelial cells. Eur J Pharmacol 2013; 718: 24-29. IF: 2.684 Jiang RH, Xu HB ( 通讯作者), Li L. Comparative roles of moxifloxacin and levofloxacin in the treatment of pulmonary multidrug-resistant tuberculosis: a retrospective study. Int J Antimicrob Ag 2013; 42: 36-41. IF 4.259 Xu HB, Jiang RH, Li L. Treatment outcomes for Mycobacterium avium complex: a systematic review and meta-analysis. Eur J Clin Microbiol Infect Dis 2014; 33(3): 347-358. IF 2.668 Xu HB, Xu LZ, Mao XP, Fu J. Guggulsterone of Commiphora mukul resin reverses drug resistance in imatinib-resistant leukemic cells by inhibiting cyclooxygenase-2 and P-glycoprotein. Phytomedicine 2014; 21: 1004-1009. IF 3.126 Xu HB, Shen ZL, Fu J, Xu LZ. Reversal of doxorubicin resistance by guggulsterone of Commiphoramukul in vivo. Phytomedicine 2014; 21: 1221-1229. IF 3.126 徐陆忠，徐宏彬（通讯作者），周学琴。GC 法同时测定解热消炎胶囊中 4 种挥发性组分。中成药 2014；36（11）：2319-2322. 苏瑞，李玲，徐宏彬（通讯作者）。复方苦参注射液对胃肠道恶性肿瘤辅助治疗的临床观察。中国医院药学杂志 2015；35（4）：322-325。 Xu HB, Huang F, Su R, Shen FM, Lv QZ. Capecitabine plus oxaliplatin (XELOX) compared with 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOXs) in advanced gastric cancer: Meta-analysis of randomized controlled trials. Eur J Clin Pharmacol 2015; 71: 589-601. IF 2.71 Jiang RH, Xu HB（通讯作者）, Fu J. Outcomes of Chinese Herb Medicine for the treatment of multidrug-resistant tuberculosis: a systematic review and meta-analysis. Complement Ther Med 2015; 23: 544-554. IF 1.935 Hou LC, Huang F, Xu HB（通讯作者）. Does celecoxib improve the efficacy of chemotherapy for advanced non-small cell lung cancer? Br J Clin Pharmacol 2015; 81(1): 23-32. IF 3.83 Xu HB, Shen FM, Lv QZ. Celecoxib enhanced the cytotoxic effect of cisplatin in drug-resistant human gastric cancer cells by inhibition of cyclooxygenase-2. Eur J Pharmacol 2015; 769: 1-7. IF 2.73 Xu HB, Shen FM, Lv QZ. Celecoxib enhanced the cytotoxic effect of cisplatin in chemo-resistant gastric cancer xenograft mouse models through a cyclooxygenase-2-dependent manner. Eur J Pharmacol 2016; 776: 1-8. IF 2.896 Xu HB,Yu J , Xu LZ, Fu J. Regulation of P-glycoprotein efflux activity by Z-guggulsterone of Commiphora mukul at the blood-brain barrier. J Neurol Sci 2016; 363: 147-152. IF 2.295 Xu HB, Fu J, Huang F, Yu J. Guggulsterone sensitized drug-resistant human hepatocarcinoma cells to doxorubicin through a Cox-2/P-gp dependent pathway. Eur J Pharmacol 2017; 803: 57-64.IF 2.896 Xu HB, Jiang RH, Sheng HB. Meta-analysis of the effects of Bifidobacterium preparations for the prevention and treatment of pediatric antibiotic-associated diarrhea in China. Complement Ther Med 2017; 33: 105-113. IF 2.013