陈光全 - 同济大学

个人简介

同济大学医学院硕士研究生导师。以第一或者通讯作者共发表SCI论文7篇，其中中科院1区的3篇，累计影响因子40。合著英文专著1本。作为项目负责人主持科研项目4项，包括国家自然科学基金项目1项，上海市母胎重点实验室开放课题1项和校局级项目2项。曾在国外分子知名分子生物实验室参与研发，参与研发构建150万人的遗传基因数据库。长期从事第二代测序及分子诊断，分析了超过5000例的遗传罕见病基因测序数据。首次解析了环境微塑料污染对于胎盘及胎儿的毒性分子机制，成果表与环境健康领域中科院1区Science of The Total Environment（IF=9.8）杂志上。

研究领域

医学遗传学，产前分子诊断，环境污染对母婴健康的影响

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Chen Guangquan, Xiong Shiyi,et al. Maternal exposure to polystyrene nanoparticles retarded fetal growth and triggered metabolic disorders of placenta and fetus in mice. Science of the Total Environment , 2023, 854: 158666 (IF:9.8) Chen Guangquan, van Straalen N M, Roelofs D. The ecotoxicogenomic assessment of soil toxicity associated with the production chain of 2, 5- furandicarboxylic acid (FDCA), a candidate bio-based green chemical building block. Green Chemistry. 2016; 18(16):4420-4431（IF:9.8） Chen Guangquan, den Braver M W, van Gestel C A, et al. Ecotoxicogenomic assessment of diclofenac toxicity in soil. Environmental Pollution. 2015; 199(C):253-260（IF:8.9） Qiao J, Chen Y, Lu Y, Wang T, Li X, Qin W, Li A, Chen Guangquan. A Syndrome of Variable Allergy, Short Stature, and Fatty Liver. Frontiers in Genetics. 2022; 12:784135（IF:3.7） Chen, Guangquan, de Boer T E, Wagelmans M, et al. Integrating transcriptomics into triad-based soil-quality assessment. Environmental toxicology and chemistry. 2014; 33(4):900-909（IF:4.1） Xi Y*, Chen Guangquan*,Lei C, et al. Expanded carrier screening in Chinese patients seeking the help of assisted reproductive technology. Molecular genetics & Genomic medicine. 2020; 8(9):e1340（IF:2.0） Chen Guangquan*, Xiong S*, Zou G, et al. A 6.3 Mb maternally derived microduplication of 20p13p12.2 in a fetus with Brachydactyly type D and related literature review. Molecular Cytogenetics. 2022; 15(1):6 (IF:1.3） Swart E, de Boer T E, Chen Guangquan, et al. Species-specific transcriptomic responses in Daphnia magna exposed to a bio-plastic production intermediate. Environmental Pollution. 2019; 252(Pt A):399-408（IF:8.9） Kong L, Li S, Zhao Z, Feng J, Chen Guangquan, et al. Haplotype-Based Noninvasive Prenatal Diagnosis of 21 Families With Duchenne Muscular Dystrophy: Real-World Clinical Data in China. Frontiers in Genetics. 2021; 12:791856（IF:3.7） Zhu D, Wei X, Chen Guangquan, et al. Chromosomal abnormalities in recurrent pregnancy loss and its association with clinical characteristics[J]. Journal of Assisted Reproduction and Genetics, 2023: 1-8.（IF:3.1） Xiong S, Wu F, Chen Guangquan,, et al. Prenatal Phenotypical Discrepancy in Monozygotic Twins with Tuberous Sclerosis Complex. Maternal-Fetal Medicine, 2022, 4(04): 286-289.（IF:1.0） Qiu hao, li jingjing, Chen Guangquan et al , 微/纳塑料穿透机体生物屏障及其健康效应, Chinese Science Bulletin (科学通报), 2023, ISSN 0023-074X (核心期刊, IF:1.1)