个人简介
专注于常见病原菌致病机制的基础研究，尤其是肠道病原菌。在肠出血型大肠埃希菌（EHEC）VI型分泌系统（T6SS）的研究中，取得了重要的原创成果，提出了T6SS有助于增强EHEC在宿主巨噬细胞内的生存水平，从而表现出对宿主的毒力作用。标志性成果发表在《PLOS Pathogens》上。他的发现在中华医学会第十二次全国临床微生物学术年会上被评为大会论文一等奖。目前以一作或合作发表论文共10篇，其中SCI 收录5篇。
近期论文
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Wan B#, Zhang Q#, Ni J, Li S, Wen D, Li J, Xiao H, He P, Ou HY, Tao J, Teng Q, Lu J, Wu W*, Yao YF*, Type VI secretion system contributes to Enterohemorrhagic Escherichia coli virulence by secreting catalase against host reactive oxygen species (ROS). PLOS Pathogens, 2017, 13(3): p. e1006246
Wan B, Zhang Q, Tao J, Zhou A, Yao YF*, Ni J*, Global transcriptional regulation by H-NS and its biological influence on the virulence of Enterohemorrhagic Escherichia coli. Gene, 2016, 588(2): 115-123
Chen WW#, Wan B#, Zhang R, Cao W, Liang L, Zhao YL, Chen J*, Yue J*, Genetic Polymorphisms of miR-149 Associated with Susceptibility to Both Pulmonary and Extrapulmonary Tuberculosis. Genet Test Mol Biomarkers. 2019 Jul;23(7):442-447. doi: 10.1089/gtmb.2019.0003. Epub 2019 Jun 20
Zhang Q, Wan B, Zhou A, Ni J, Xu Z, Li S, Tao J, Yao Y*, Whole genome analysis of an MDR Beijing/W strain of Mycobacterium tuberculosis with large genomic deletions associated with resistance to isoniazid, Gene, 2016, 582(2): 128-136
Zhang Q, Zhou A, Li S, Ni J, Tao J, Lu J, Wan B, Li S, Zhang J, Zhao S, Zhao GP, Shao F, Yao YF*, Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli, Sci Rep, 2016 Aug 3, 6: 30837
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