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主持及参与课题 国家自然科学基金面上项目,82272060,基于交换偏置的新型QSM纳米诊疗系统对肾癌分子靶向治疗先天性耐药精准预测和干预的实验研究,2023/01-2026/12,52万元,在研,主持 国家自然科学基金面上项目,81974274,构建高效智能型复合纳米诊疗系统精确评价和干预肾癌分子靶向治疗耐药的实验研究,2020/01-2023/12,55万元,在研,主持 中央高校基本科研业务费专项资金项目, 自主原创重点项目, 22120210568, 构建双模态MRI智能纳米系统高灵敏和高精度评价肾癌分子靶向治疗耐药, 2021/11- 2023/10, 30万元, 在研, 主持 国家自然科学基金面上项目,81771889,针对AD致病蛋白(Aβ)的靶向复合纳米诊疗系统的构建与应用的实验研究,2018/01-2021/12,65万元,已结题,参与 江苏省自然科学基金面上项目,BK20161219,靶向EGFR及整合素的双模态成像联合光动力治疗探针在吉非替尼耐药肺癌诊疗一体化中的研究,2016/09-2019/09,20万元,已结题,参与 南通市科技局项目,MS12015100,以整合素αvβ3为靶点的磁共振光学双模成像联合光动力治疗探针的构建及其在肿瘤靶向中的应用研究,2015/10-2018/09,6万元,已结题,主持 南通市卫生局委青年基金项目,WQ2014046,基于氧化石墨烯的多功能纳米复合体在HER-2阳性人乳腺癌诊治中的应用价值研究,2014/06-2016/05,4万元,已结题,主持

研究领域

MR与CT分子影像学的临床应用及基础研究

近期论文

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Aijun Shen#; Xianfu Men#; Xiaolong Gao; Xiaowen Xu; Chulun Shao; Zhongmin Tang; Yanyan Liu; Wenbo Bu*; Peijun Wang*; An Adaptable Nanoplatform for Integrating Anatomic and Functional Magnetic Resonance Imaging under a 3.0T Magnetic Field, Advanced Functional Materials, 2019, 29(2): 1803832. (IF=15.621) Chulun Shao#; Aijun Shen#; Meng Zhang; Xianfu Meng; Chaolin Song; Yanyan Liu; Xiaolong Gao; Peijun Wang*; Wenbo Bu*; Oxygen Vacancies-Enhanced CeO2:Gd Nanoparticles for Sensing Tumor Vascular Microenvironment by Magnetic Resonance Imaging, ACS Nano, 2018, 12(12): 12629-12637. (IF=13.709) Kun Wang#; Huilin Zhang#; Aijun Shen; Peiran Zhao; Xianfu Meng; Xiaoyan Chen; Yang Liu; Yanyan Liu; Teng Gong; Wanlu Wu; Xiangming Fang*; Peijun Wang; Wenbo Bu*; Magnetic resonance energy transfer for in vivo glutathione susceptibility weighted imaging, Biomaterials, 2020, 232: 119703.(IF=10.273) Chaolin Song#; Xianfu Meng#; Yanyan Liu*; Aijun Shen; Chulun Shao; Kun Wang; Hui Cheng; Xiangming Fang*; Peijun Wang; Wenbo Bu*, Susceptibility-weighted imaging for metabolic pathway mapping of low dosage nanoparticles in organisms, Biomaterials, 2020, 230: 119631.(IF=10.273) Yi Han; Yanchao Liu; Xiaoyi Ma; Aijun Shen; Yiqiong Liu; Nopphon Weeranoppanant; Haiqing Dong; Yan Li; Tianbin Ren; Le Kuai; Bin Li; Maomao An*; Yongyong Li*, Antibiotics armed neutrophils as a potential therapy for brain fungal infection caused by chemotherapy-induced neutropenia, Biomaterials, 2021, 274: 120849.(IF=12.479) Minghua Li; Xiaolong Gao; Chao Lin; Aijun Shen; Jing Luo; Qiongqiong Ji; Jiaqi Wu; Peijun Wang*, Journal of Nanobiotechnology, 2021, 19(1): 336. (IF=9.429) Qiansai Qiu; Ya Wen; Haiqing Dong; Aijun Shen; Xingxing Zhen; Yongyong Li*; Feng Feng*, A highly sensitive living probe derived from nanoparticle-remodeled neutrophils for precision tumor imaging diagnosis, Biomaterials science, 2019, 7(12), 5211-5220. (IF=6.183) Feng Feng, Fulin Qiang, Aijun Shen, Donghui Shi, Aiyan Fu, Haiming Li, Mingzhu Zhang, Ganlin Xia*, Peng Cao*. Dynamic contrast-enhanced MRI versus F-18-FDG PET/CT: Which is better in differentiation between malignant and benign solitary pulmonary nodules, Chinese journal of cancer research, 2018, 30 (1): 21-30. (IF=3.689) Ya Wen; Haiqing Dong*; Yan Li; Aijun Shen*; Yongyong Li*; Nano-assembly of bovine serum albumin driven by rare-earth-ion (Gd) biomineralization for highly efficient photodynamic therapy and tumor imaging, Journal of Materials Chemistry B, 2016, 4(4): 743-751. (IF=4.726) Huiyun Wen*; Haiqing Dong*; Jie Liu; Aijun Shen; Yongyong Li; Donglu Shi; Redox-mediated dissociation of PEG–polypeptide-based micelles for on-demand release of anticancer drugs, Journal of Materials Chemistry B, 2016, 4(48): 7859-7869. (IF=4.726) Aijun Shen#; Dongliang Li#; Xiaojun Cai; Chunyan Dong; Haiqing Dong; Huiyun Wen; Gonghua Dai; Peijun Wang*; Yongyong Li*; Multifunctional Nanocomposite based on Graphene Oxide for in Vitro Hepatocarcinoma Diagnosis and Treatment, Journal of Biomedical Materials Research Part A, 2012, 100A(9):2499-2506. (IF=3.231) Aijun Shen, Haiqing Dong, Huiyun Wen, Men Xu, Yongyong Li*, Peijun Wang*. Gadolinium-Based Contrast Agents for Tumor Targeting Imaging. Progress in Chemistry, 2011, 23(4): 772-780.

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