张贝 - 同济大学

研究领域

阿尔茨海默病及帕金森病病因及相关机制研究神经干细胞技术在神经退行性疾病中保护及神经网络重建中的作用与机制研究

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Wenxin Zhang(#)，Weihao Di，Jian Zhao， Bei Zhang(*), Ying Wang(*).Generation of a SIAISi004-A hiPSC line from PBMCs of a 74 year-old Alzheimer’s disease woman by non-integrating sendai virus mediated reprogramming. Stem Cell Research, 2021 August 6. Bei Zhang(#) ,Hong‐Xiang Yu(#) ,Nan Zhi(#) ,Can Cui ,Ying‐Ying Han ,Min Hu ,Hao Shen(*) ,Huan Bao(*) ,Gang Li(*).Association of HMOX‐1 with sporadic Alzheimer’s disease in southern Han Chinese. Eur J Neurol. 2021 April 17. Wenxin Zhang(#), Yishi Hua , Weihao Di , Jinghui Guo , Qiuting Dai , Jian Zhao , Bei Zhang (*), Ying Wang (*).Generation of a human induced pluripotent stem cell line (SIAISi011-A) from a 61-year-old Chinese Han healthy female donor. Stem Cell Research, 2021 Jan 12;51:102173. Kui Chen2#, Meng-Ruo Guo 1#, Yue Zhang 1#, Gang Li1, Yi Liu3*, Bei Zhang1* ，Association between MMP16 rs60298754 and clinical phenotypes of Parkinson’s disease in southern Chinese，Neurological Sciences, 2020 Nov 25. Qiuting Dai 1, Wenxin Zhang 1, Jinghui Guo 1, Weihao Di 1, Jian Zhao 1, Bei Zhang 2, Ying Wang 3，Generation of an induced pluripotent stem cell line (SIAISi003-A) from a 79-year-old patient with Alzheimer‘s disease having APOE3/4 genetic background ,Stem Cell Res, 2020 Aug 5;48 Yueyu Tang 1, Yingying Han 1, Hongxiang Yu 1, Bei Zhang 2, Gang Li 3 Increased GABAergic development in iPSC-derived neurons from patients with sporadic Alzheimer‘s disease，Neurosci Lett，2020 Sep K Chen 1, Y Tang 2, X Zhao 3, C Hou 4, G Li 5, B Zhang 5 ， Association of IL1R2 rs34043159 With Sporadic Alzheimer's Disease in Southern Han Chinese，Eur J Neurol 2020 May 13. Bei Zhang 1, Can Cui 1, Hongxiang Yu 1, Gang Li 2 ，Association Between ZNF184 and Symptoms of Parkinson‘s Disease in Southern Chinese，Neurol Sci 2020 Mar 3. Bei Zhang a#, Yishu Wang a#, Jing Peng a, Yong Hao a*, Yangtai Guan a*， Generation of a human induced pluripotent stem cell line from an epilepsy patient carrying mutations in the PIK3R2 gene, Stem Cell Res, 2020 Apr;44 Hong-Xiang Yu1 & Meng-Ruo Guo1 & Gang Li1 & Bei Zhang1, Association between fatigue and motor progression in Parkinson’s disease in southern Chinese,Neurological Sciences, 2019 Sep 4. Xin-Yi Wang 1#, Ying-Ying Han 1#, Gang Li 1*, Bei Zhang 1*，Association between autonomic dysfunction and olfactory dysfunction in Parkinson’s Disease in southern Chinese. BMC neurology ,2018,12 Bei Zhang，Ying Wang，Hui Li, Qiongqiong Li，Suya Sun, Shengdi Chen，Neuroprotective effects of salidroside throughPI3K/Akt pathway activation in Alzheimer’s disease models，Drug Des Devel Ther,2016,10:1-9 Bei Zhang, Li-Ling WangHuai-Bin Cai, Sheng-Di Chen ,Gang Wang， MicroRNA-146a represses LRP2 translation and leads to cell apoptosis in Alzheimer's disease，FEBS Letters, 2016 Jul;590(14):2190-200 Zhang B, Li Q, Chu X, Chen S, Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3β phosphorylation in a tau transgenic Drosophila model of Alzheimer’s disease, Transl Neurodegener. 2016(5):21