李开春 - 同济大学

个人简介

讲师、医学博士、硕士生导师，同济大学附属上海市第四人民医院肿瘤科副主任医师，科主任。长期从事恶性肿瘤的综合治疗，尤其免疫药物和靶向药物的治疗。现任中国医药教育协会疑难肿瘤专业委员会常务委员、中国抗癌协会中西医整合肿瘤专业委员会委员、长三角肿瘤专科联盟理事、上海市中西医结合学会肿瘤微创专业委员会常务委员、上海市抗癌协会肿瘤生物治疗专业委员会委员、上海市抗癌协会肿瘤药物临床研究专业委员会委员等。主持并完成上海市卫健委课题2项、虹口区科委课题1项、吴阶平医学课题1项，在研上海市第四人民医院启动课题2项(科研经费100万)。作为第一作者/通讯作者发表SCI收录论文10篇，中文核心期刊21篇，包括中华系列3篇。

研究领域

局部晚期食管癌免疫治疗新型生物标志物的探索

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Siyue Zhang#; Fangyuan Xie#; Kaichun Li#; He Zhang#; You Yin#; Yuan Yu; Guangzhao Lu; Shihao Zhang; Yan Wei; Ke Xu; Yan Wu; Hong Jin; Lan Xiao; Leilei Bao; Yulin Li*; Ying Lu*; Jie Gao*; Gold Nanoparticle-Directed Autophagy Intervention for Antitumor Immunotherapy via Inhibiting Tumor Associated Macrophage M2 Polarization, Acta Pharmaceutica Sinica B, 2022, 12(7): 3124-3138. <2022 IF: 14.903> Xinxin Wang#; Haitao Gu#; Kaichun Li#; Jiayun Lin; Yiming Zhu; Wensheng Deng*; DPP4 inhibitor reduces portal hypertension in cirrhotic rats by normalizing arterial hypocontractility, Life Sciences, 2021, 284: 119895. <2022 IF: 6.780> Kaichun Li*; Liying Pang; Xiaorong Pan; Shaonan Fan; Xinxin Wang; Qiaoyun Wang; Ping Dai; Wei Gao*; Jie Gao*; GE11 Modified PLGA/TPGS Nanoparticles Targeting Delivery of Salinomycin to Breast Cancer Cells, Technology in Cancer Research & Treatment, 2021, 20: 15330338211004954. <2021 IF: 3.399> Kaichun Li*; Qiaoyun Wang; Yanyan Lu; Xiaorong Pan; Long Liu; Shiyu Cheng; Bingxiang Wu; Zongchang Song*; Wei Gao*; Machine learning based tissue analysis reveals Brachyury has a diagnosis value in breast cancer, Bioscience Reports, 2021, 41(4): BSR20203391. <2022 IF: 3.976> Qingliang Fang#*; Kaichun Li#; Lei Wang; Xianglian Gu; Renjie Song; Song Lu; Targeted Inhibition of CCL22 by miR-130a-5p Can Enhance the Sensitivity of Cisplatin-Resistant Gastric Cancer Cells to Chemotherapy, Cancer Management and Research, 2020, 12: 3865-3875. <2022 IF: 3.602> Bing Dan#; Jie Luo#; Kaichun Li*; Shiyu Chen; Prognostic Value of miR-375 for Survival Outcomes in Various Cancers: A Systematic Review and Meta-Analysis, Oncology Research and Treatment, 2018, 41(1-2): 47-50. <2022 IF: 2.844> Kaichun Li; Mingzhen Ying; Dan Feng; Jie Du; Shiyu Chen; Bing Dan; Cuihua Wang; Yajie Wang*; Brachyury promotes tamoxifen resistance in breast cancer by targeting SIRT1, Biomedicine & Pharmacotherapy, 2016, 84: 28-33. <2022 IF: 7.419> Kaichun Li; Mingzhen Ying; Dan Feng; Yan Chen; Jingwen Wang; Yajie Wang*; SMC1 promotes epithelial-mesenchymal transition in triple-negative breast cancer through upregulating Brachyury, Oncology Reports, 2016, 35: 2405-2412. <2022 IF: 4.136> Kaichun Li; Mingzhen Ying; Dan Feng; Jie Du; Shiyu Chen; Bing Dan; Cuihua Wang; Yajie Wang*; Fructose-1,6-bisphosphatase is a novel regulator of Wnt/β-Catenin pathway in breast cancer, Biomedicine & Pharmacotherapy, 2016, 84: 1144-1149. <2022 IF: 7.419> Kaichun Li; Jin Li*; Current Molecular Targeted Therapy in Advanced Gastric Cancer: A Comprehensive Review of Therapeutic Mechanism, Clinical Trials, and Practical Application, Gastroenterology Research and Practice, 2016, 2016: 4105615. <2022 IF: 1.919> 李开春; 程诗宇; 杜杰; 李进*; 转移性或局部晚期胃癌的二线治疗选择, 中华肿瘤杂志, 2016, 38(10): 721-724. < 专题综论> 李开春*; 陈佳艳; 老年晚期肺癌患者药物治疗的选择, 中华肿瘤杂志, 2015, 37(10): 721-724. < 专题综论> 李开春; 曾晓颖; 匡春香; 江玉波; 戴兆云*; 碘化亚油酸及5-氟尿嘧啶酯抑制肝细胞癌生长的初步研究, 中华肝脏病杂志, 2013, 21(5): 372-375. < 论著>