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长期从事关于缺血性疾病的促血管新生疗法的基础与临床转化研究,目前以第一作者或通讯作者身份发表SCI论文7篇,参与其余论著共计十余篇,作为项目负责人主持国家自然科学基金1项,同济大学青年人才培育优青项目1项,参编心血管病专著1本。 主持科研项目情况 国家自然科学基金青年基金,81801379,脉冲电磁场通过激活HuR调控 Sirt1/eNOS 信号通路改善老年鼠血管老化的作用及机制研究 同济大学青年人才培育优青项目,PA2018001538,脉冲电场磁场通过激活HuR/Sirt1/eNOS信号通路改善衰老血管内皮细胞功能障碍的机制研究

研究领域

缺血性疾病的血管新生疗法

近期论文

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Rui-Lin Li#, Jing-Juan Huang#, Yi-Qin Shi#, An Hu, Zhao-Yang Lu, Liang Weng, Shen-Qi Wang, Yi-Peng Han, Lan Zhang*, Chang-Ning Hao*, Jun-Li Duan*,Pulsed?electromagneticfield?improves?postnatal?neovascularization?in?response?to?hindlimb?ischemia,Am J Transl Res. 2015; 7(3): 430–444. Rui-Lin Li#, Zhao-Yang Lu#, Jing-Juan Huang#, Jia Qi, An Hu, Zhi-Xiao Su, Lan Zhang, Yue Li*, Yi-Qin Shi*, Chang-Ning Hao*, Jun-Li Duan*,SRT1720, a SIRT1 specific activator, protected H2O2-induced senescent endothelium.Am J Transl Res. 2016; 8(7): 2876–2888. Zhao-Yang Lu#, Rui-Lin Li#, Hong-Sheng Zhou, Jing-Juan Huang, Zhi-Xiao Su, Jia Qi, Lan Zhang, Yue Li*, Yi-Qin Shi*, Chang-Ning Hao*, Jun-Li Duan*, Therapeutic ultrasound reverses peripheral ischemia in type 2 diabetic mice through PI3K-Akt-eNOS pathway .Am J Transl Res. 2016; 8(9): 3666–3677. Zhao-Yang Lu#, Rui-Lin Li#, Hong-Sheng Zhou#, Jing-Juan Huang, Jia Qi, Zhi-Xiao Su, Lan Zhang, Yue Li*, Yi-Qin Shi*, Chang-Ning Hao*, Jun-Li Duan*, Rescue of hypertension-related impairment of angiogenesis by therapeutic ultrasound. Am J Transl Res. 2016; 8(7): 3087–3096. Huang JJ#, Shi YQ#, Li RL#, Hu A*, Lu ZY, Weng L, Han YP, Wang SQ, Zhang L* , Hao CN* and Duan JL*, Therapeutic ultrasound protects HUVECs from ischemia/hypoxia-induced apoptosis via the PI3K-Akt pathway. Am J Transl Res. 2017 Apr 15;9(4):1990-1999. Cheng-Hui Fan#, Ying Hao#, Yong-Hua Liu, Xiao-Lin Li, Zhen-Hao Huang, Yu Luo*, Rui-Lin Li*, Anti-inflammatory effects of rosuvastatin treatment on coronary artery ectasia patients of different age groups. BMC Cardiovasc Disord. 2020; 20: 330. Rui-Lin Li#, Shu-Guang Chu, Yu Luo, Zhen-Hao Huang, Ying Hao, Cheng-Hui Fan*, Atypical presentation of SARS-CoV-2 infection: A case report. World J Clin Cases. 2020 Apr 6; 8(7): 1265–1270.

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