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个人简介

皮劲江医师作为一名医学科研工作者,2018年毕业于同济大学医学院,毕业之后进入同济大学附属东方医院心血管内科从事临床及研究工作,临床亚专业方向为冠脉介入方向,研究工作主要从事心血管疾病分子机制研究,博士期间以第一作者在Circulation Research、Theranostics、BMC Ophthalmolog等国际SCI杂志发表论文3篇,署名SCI论文5篇,参与申请专利1项,2016年-2017年以联合培养博士身份赴美国宾夕法尼亚大学参与表观遗传学等相关工作,参与的工作发表在Cancer Cell及Science Translational Medicine上,回国工作后继续从事心血管疾病方面工作,期间以共一作者在Circulation,参与作者在Circulation Research发表相关研究成果,参与申请专利一项,主持国家自然科学基金两项,参与国自然面上项目、重大研发计划(培育项目)、国家重点研究计划共计5项,继续从事血管损伤修复、再生、重塑,冠心病动脉粥样硬化形成和发展机制以及干细胞分裂机制的研究,除基础科研以外还致力于心血管疾病预防,与影像科心血管科合作收集冠脉造影病人样本库,分析冠状动脉斑块与心血管危险因素关系,为临床早期筛查高危人群提供有价值的依据;与社区合作建立老年人心血管疾病样本库,随访5年以上体检老年人,干预心血管可控危险因素。

研究领域

血管新生,血管损伤修复,冠心病心衰机制研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Zhuang T, Liu J, Chen X, Zhang L, Pi J, Sun H, Li L, Bauer RC, Wang H, Yu Z, Zhang Q, Tomlinson B, Chan P, Zheng X, Morrisey E, Liu Z, Reilly M, Zhang Y. Endothelial Foxp1 Suppresses Atherosclerosis via Modulation of Nlrp3 Inflammasome Activation. Circ Res. 2019 Jul 18. doi: 10.1161/CIRCRESAHA.118.314402. Liu J, Zhuang T, Pi J, Chen X, Zhang Q, Li Y, Wang H, Shen Y, Tomlinson B, Chan P, Yu Z, Cheng Y, Zheng X, Reilly M, Morrisey E, Zhang L, Liu Z, Zhang Y. Endothelial Foxp1 Regulates Pathological Cardiac Remodeling Through TGF-β1-Endothelin-1 Signal Pathway. Circulation. 2019 Jun 10. doi: 10.1161/CIRCULATIONAHA.119.039767. 4.Wang Y, Liu J, Chen X, Sun H, Peng S, Kuang Y, Pi J, Zhuang T, Zhang L, Yu Z, Tomlinson B, Chan P, Chen Y, Zhang Y, Li Y. Dysfunctional endothelial-derived microparticles promote inflammatory macrophage formation via NF-кB and IL-1β signal pathways. J Cell Mol Med. 2019 Jan;23(1):476-486. doi: 10.1111/jcmm.13950. Epub 2018 Oct 18. Pi J, Liu J, Zhuang T, Zhang L, Sun H, Chen X, Zhao Q, Kuang Y, Peng S, Zhou X, Yu Z, Tao T, Tomlinson B, Chan P, Tian Y, Fan H, Liu Z1, Zheng X, Morrisey E, Zhang Y. Elevated Expression of miR302-367 in Endothelial Cells Inhibits Developmental Angiogenesis via CDC42/CCND1 Mediated Signaling Pathways. Theranostics 2018; 8(6): 1511-1526. Yuan J, Hu Z, Mahal BA, Zhao SD, Kensler KH, Pi J, Hu X, Zhang Y, Wang Y, Jiang J, Li C, Zhong X, Montone KT, Guan G, Tanyi JL, Fan Y, Xu X, Morgan MA, Long M, Zhang Y, Zhang R, Sood AK, Rebbeck TR, Dang CV, Zhang L. Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers. Cancer Cell. 2018 Oct 8;34(4):549-560.e9. Pi J, Tao T, Zhuang T, Sun H, Chen X, Liu J, Cheng Y, Yu Z, Zhu HH, Gao WQ, Suo Y, Wei X, Chan P, Zheng X,Tian Y, Morrisey E, Zhang L, Zhang Y. A MicroRNA- 302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability. Circulation Research. 2017 Jan 6; 120(1):85-98. 2017 Pi J, Cheng Y, Sun H, Chen X, Zhuang T, Liu J, Li Y, Chang H, Zhang L, Zhang Y et al: Apln-CreERT:mT/mG reporter mice as a tool for sprouting angiogenesis study. BMC ophthalmology 2017, 17(1):163. Yang L, Zhang Y, Shan W, Hu Z, Yuan J, Pi J, Wang Y, Fan L, Tang Z, Li C et al: Repression of BET activity sensitizes homologous recombination-proficient cancers to PARP inhibition. Science translational medicine 2017, 9(400). Kuang Y, Li X, Chen X, Sun H, Tomlinson B, Chan P, Zheng L, Pi J, Peng S, Wu H, Ding X, Qian D, Shen Y, Yu Z, Fan L,Chen M, Fan H, Liu Z, Zhang Y. Higher prevalence of elevated LDL-C than non-HDL-C and low statin treatment rate in elderly community-dwelling Chinese with high cardiovascular risk. Sci Rep. 2016 Sep 30;6:34268. doi: 10.1038/srep34268.

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