个人简介
长期从事心血管疾病尤其动脉粥样硬化疾病的相关基础与临床研究,作为主持人独立完成国家自然科学基金一项、上海市科委创新项目一项、中国心血管健康联盟基金两项、临床研究两项,作为主要负责人参与国家级、上海市、浙江省科委多个项目研究;在探索冠心病发病机制、冠脉植入支架前后计算机重建等方面积累了较丰富的经验,发表SCI论文20余篇。
研究领域
常见心血管疾病临床诊疗技能,危重心血管疾病诊治、冠心病介入诊治、复杂冠脉病变介入治疗技术
动脉粥样硬化疾病的相关基础与临床研究,冠脉植入支架前后计算机重建技术
近期论文
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Haoran Ding, Guoqi Zhu, Hao Lin, Jiapeng Chu, Deqiang Yuan, Yi’an Yao, Yanhua Gao, Fei Chen*, Xuebo Liu*. Screening of Potential Circulating Diagnostic Biomarkers and Molecular Mechanisms of Systemic Lupus Erythematosus-Related Myocardial Infarction by Integrative Analysis., Journal of Inflammation Research, 2023,16:3119-3134. (通讯作者)
Guoqi Zhu, Yanhua Gao, Jun Qian, Yan Lai, Hao Lin, Chengxing Liu, Fei Chen* and Xuebo Liu*. Comprehensive analysis of atherosclerotic plaques reveals crucial genes and molecular mechanisms associated with plaque progression and rupture. FRONTIERS IN CARDIOVASCULAR MEDICINE,2023:951542. (通讯作者)
Deqiang Yuan, Jiapeng Chu, Hao Lin, Guoqi Zhu, Jun Qian, Yunan Yu, Tongqing Yao, Fan Ping, Fei Chen* and Xuebo Liu*. Mechanism of homocysteine-mediated endothelial injury and its consequences for atherosclerosis. FRONTIERS IN CARDIOVASCULAR MEDICINE,2023:1109445. (通讯作者)
Jun Qian, Yanhua Gao, Yan Lai, Zi Ye, Yian Yao, Keke Ding, Jing Tong, Hao Lin, Guoqi Zhu, Yunan Yu, Haoran Ding, Deqiang Yuan, Jiapeng Chu, Fei Chen* and Xuebo Liu*. Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction. FRONTIERS IN IMMUNOLOGY,2022:908815. (通讯作者)
Jing Tong, Bing Ji, Yan-Hua Gao, Hao Lin, Fan Ping, Fei Chen*, Xue-Bo Liu*. Sirt6 regulates autophagy in AGE-treated endothelial cells via KLF4. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES,2022,32:755-764. (通讯作者)
Jun Qian, Jiyong Zan, Lijun Kuang, Lin Che, Yunan Yu, Ting Shen, Jiani Tang, Fei Chen*, Xuebo Liu*. A predictive nomogram of bleeding risk in patients with atrial fibrillation after drug-eluting stent implantation. Ann Transl Med, 2021,9(3):193. (通讯作者)
Jun Qian, Lijun Kuang, Lin Che, Fei Chen*, Xuebo Liu*. Maximum blood glucose levels during hospitalisation to predict mortality in patients with acute coronary syndrome: a retrospective cohort study. BMJ Open,2020,10:e042316. (通讯作者)
Xiaolu Jiang, Yanqiu Zeng, Shixiao Xiao*, Shaojie He, Caizhi Ye, Yu Qi, Jiangsheng Zhao, Dezhi Wei, Muhua Hu, Fei Chen*. Automatic Detection of Coronary Metallic Stent Struts Based on YOLOv3 and R-FCN. Computational and Mathematical Methods in Medicine. 2020:1793517. (通讯作者)
Ye Zi, Yao Yi-An, Ji Bing, Lai Yan, Tong Jing, Guan Chun-Yu, Ping Fan, Lin Hao, Tang Jia-Ni, Hou Han-Jin, Chen Fei*,Liu Xue-Bo*. Sirt6-induced autophagy restricted TREM-1-mediated pyroptosis in ox-LDL-treated endothelial cells: relevance to prognostication of patients with acute myocardial infarction. Cell death discovery. 2019,5:88. (通讯作者)