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Qiwei Liu, Yumei Li, Yun Feng, Chaojie Liu, Jieliang Ma, Yifei Li, Huifen Xiang, Yazhong Ji, Yunxia Cao, Xiaowen Tong, Zhigang Xue Single-cell analysis of differences in transcriptomic profiles of oocytes and cumulus cells at GV, MI, MII stages from PCOS patients. Sci Rep, 2016. 6: p. 39638 ( corresponding author)
Ping Lu, Xiaolong Chen, Yun Feng, Qiao Zeng, Cizhong Jiang, Xianmin Zhu，Guoping Fan , Zhigang Xue*.Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient during neuronal differentiation. Sci China Life Sci, 2016. 59(11): p. 1093-1105. ( corresponding author)
Youjin Hu, Kevin Huang, Qin An, Guizhen Du, Ganlu Hu, Jinfeng Xue, Xianmin Zhu, Cun-Yu Wang,Zhigang Xue*,Guoping Fan*.. Simultaneous profiling of transcriptome and DNA methylome from a single cell. Genome Biology. 2016; 17:88. ( corresponding author)
Shuyang Xu, Xianmin Zhu, Hong Li, Youtian Hu, Jinping Zhou, Di He, Yun Feng,Lina Lu, Guizhen Du, Youjin Hu, Tiancheng Liu, Zhen Wang, Guohui Ding, Jiayu Chen,Shaorong Gao, Fang Wu, Zhigang Xue, Yixue Li, Guoping Fan* The 14th Ile residue is essential for Leptin function in regulating energy homeostasis in rat. Scientific Reports. 2016; 6:28508.
Ganlu Hu, Kevin Huang, Youjin Hu, Guizhen Du, Zhigang Xue, Xianmin Zhu,Guoping Fan. Single-cell RNA-seq reveals distinct injury responses in different types of DRG sensory neurons. Scientific Reports. 2016; 6:31851.
Lina Lu,Bo Lv,Kevin Huang,Zhigang Xue,Xianmin Zhu,Guoping Fan. Recent advances in preimplantation genetic diagnosis and screening. J Assist Reprod Genet. 2016; 33: P.1129–34.
Hailiang Liu, Yongchang Chen, Yuyu Niu, Kunshan Zhang, Yu Kang, Weihong Ge,Xiaojing Liu, Enfeng Zhao, Chencheng Wang, Shaoyun Lin, Bo Jing, Chenyang Si, Quan Lin, Xiaoying Chen, Haijun Lin, Xiuqiong Pu, Yingying Wang, Binlian Qin, Fang Wang,Hong Wang, Wei Si, Jing Zhou, Tao Tan, Tianqing Li, Shaohui Ji, Zhigang Xue, Yuping Luo, Liming Cheng, Qi Zhou, Siguang Li, Yi Eve Sun, Weizhi Ji. TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys. Cell Stem Cell. 2014;14(3): p. 323-8.
J Lingjing Jin, Zhourui Wu, Wei Xu, Xiao Hu, Jin Zhang, Zhigang Xue*, Liming Cheng. Identifying gene expression profile of spinal cord injury in rat by bioinformatics strategy. Mol Biol Rep. 2014;41(5): p. 3169-77. ( corresponding author)
Zhenshan Liu, Rongfeng Jiang, Songtao Yuan, Na Wang, Yun Feng, Ganlu Hu, Xianmin Zhu,Kevin Huang, Jieliang Ma, Guotong Xu, Qinghuai Liu, Zhigang Xue*, Guoping Fan*. Integrated analysis of DNA methylation and RNA transcriptome during in vitro differentiation of human pluripotent stem cells into retinal pigment epithelial cells. PLoS One. 2014;9(3): p. e91416. (corresponding author)
Kevin Huang, Zhourui Wu, Zhenshan Liu, Ganlu Hu, Juehua Yu, Kai H. Chang, Kee-Pyo Kim, Thuc Le, Kym F. Faull, Nagesh Rao, Andrew Gennery, Zhigang Xue, Cun-yu Wang, Matteo Pellegrini, Guoping Fan. Selective demethylation and altered gene expression are associated with ICF syndrome in human-induced pluripotent stem cells and mesenchymal stem cells. Hum Mol Genet. 2014;23(24): p. 6448-57.
Zhigang Xue#*, Kevin Huang#, Chaochao Cai, Lingbo Cai, Chunyan Jiang, Yun Feng, Zhenshan Liu, Qiao Zeng, Liming Cheng, Yi E.Sun, Jiayin Liu, Steve Horvath,Guoping Fan*. Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing. Nature. 2013;500(7464): p. 593-7. (first author and corresponding author)
Yinyin Chen, Kevin Huang, Martin N. Nakatsu, Zhigang Xue*, Sophie X.Deng*,Guoping Fan*. Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells. Hum Mol Genet. 2013;22(7): p. 1271-9. ( corresponding author)
Kevin Huang, Yin Shen, Zhigang Xue, Marina Bibikova, Craig April, Zhenshan Liu, Linzhao Cheng, Andras Nagy, Matteo Pellegrini, Jian-Bing Fan, Guoping Fan. A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells. Stem Cell Reports. 2014;2(1): p. 36-43.
Ganlu Hu, Kevin Huang, Juehua Yu, Sailesh Gopalakrishna-Pillai, Jun Kong, He Xu,Zhenshan Liu, Kunshan Zhang, Jun Xu, Yuping Luo, Siguang Li, Yi E. Sun, Linda E.Iverson, Zhigang Xue*, Guoping Fan*. Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells. PLoS One. 2012;7(7): p. e37224. ( corresponding author)
Zhourui Wu,Kevin Huang,Juehua Yu,Thuc Le,Masakasu Namihira,Yupeng Liu,Jun Zhang, Zhigang Xue,Liming Cheng,Guoping Fan. Dnmt3a regulates both proliferation and differentiation of mouse neural stem cells. J Neurosci Res. 2012;90(10): p. 1883-91.
Anyou Wang, Kevin Huang, Yin Shen, Zhigang Xue, Chaochao Cai, Steve Horvath, Guoping Fan. Functional modules distinguish human induced pluripotent stem cells from embryonic stem cells. Stem Cells Dev. 2011;20(11): p. 1937-50.
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