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Liu S, Guan L, Peng C, Cheng Y, Cheng H, Wang F, Ma M, Zheng R, Ji Z, Cui P, Ren Y, Li L, Shi C, Wang J, Huang X, Cai X, Qu D, Zhang H, Mao Z, Liu H, Wang P, Sha W, Yang H,* Wang L,* Ge B* (2023) Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival. Cell Host & Microbe (accepted)
Wang F#, Zhao M#, Chang B#, Zhou Y, Wu X, Ma M, Liu S, Cao Y, Zheng M, Dang Y, Xu J, Chen L, Liu T, Tang F, Ren Y, Xu Z, Mao Z, Huang K, Luo M, Li J*, Liu H*, Ge B*. (2022) Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS. Molecular Cell. 82(11):2032-2049.e7.
Yang H#, Wang F#, Guo X#, Liu F#, Liu Z, Wu X, Zhao M, Ma M, Liu H, Qin H, Wang L, Tang T, Sha W, Wang Y, Chen J, Huang X, Wang J, Peng C, Zheng R, Tang F, Zhang L, Wu C, Oehlers SH, Song Z, She J, Feng H, Xie X, Ge B*. (2021) Interception of host fatty acid metabolism by mycobacteria under hypoxia to suppress anti-TB immunity. Cell Discovery 7(1):90. doi: 10.1038/s41421-021-00301-1.
Wu X#, Wu Y#, Zheng R#, Tang F, Qin L, Lai D, Zhang L, Chen L, Yan B, Yang H, Wang Y, Li F, Zhang J, Wang F, Wang L, Cao Y, Ma M, Liu Z, Chen J, Huang X, Wang J, Jin R, Wang P, Sun Q, Sha W, Lyu L, Moura-Alves P, Dorhoi A, Pei G, Zhang P, Chen J, Gao S, Randow F, Zeng G, Chen C, Ye XS*, Kaufmann SHE*, Liu H*, Ge B*. (2021) Sensing of mycobacterial arabinogalactan by galectin-9 exacerbates mycobacterial infection. EMBO Rep. 22(7):e51678.
Zhao M#, Wang F#, Wu J#, Cheng Y, Cao Y, Wu X, Ma M, Tang F, Liu Z, Liu H*, Ge B*. (2021) cGAS is a micronucleophagy receptor for the clearance of micronuclei. Autophagy. 22:1-17.
Wang L#, Wu J#, Li J#, Yang H, Tang T, Liang H, Zuo M, Wang J, Liu H, Liu F, Chen J, Liu Z, Wang Y, Peng C, Wu X, Zheng R, Huang X, Ran Y, Rao Z*, Ge B* (2020) Host-mediated ubiquitination of a mycobacterial protein suppresses immunity. Nature 577, 682-688. (Highlighted by Cell Host & Microbe, Science Bulletin)
Wang L#, Liu Z#, Wang J, Liu H, Tang T, Li H, Yang H, Qin L, Ma D, Chen J, Liu F, Zheng R, Song P, Zhou Y, Cui Z, Wu X, Wu J, Huang X, Wu C, Chen X, Zeng G, Ge B*. (2019) Oxidization of TGF β-activated kinase (TAK1) by MPT53 is required for immunity to Mycobacterium tuberculosis. Nature Microbiology 4, 1378–1388
Wang L, Zhou Y, Chen Z, Sun L, Wu J, Li H, Liu F, Wang F, Yang C, Yang J, Leng Q, Zhang Q, Xu A, Shen L, Sun J, Wu D, Fang C, Lu H*, Yan D*, Ge B*. (2019) PLCβ2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1. Nature Communications 14;10(1):746.
Liu H#, Zhang H#, Wu X#, Ma D, Wu J, Wang L, Jiang Y, Fei Y, Zhu C, Tan R, Jungblut P, Pei G, Dorhoi A, Yan Q, Zhang F, Zheng R, Liu S, Liang H, Liu Z, Yang H, Chen J, Wang P, Tang T., Peng W, Hu Z, Xu Z, Huang X, Wang J, Li H, Zhou Y, Liu F, Yan D, Kaufmann SH, Chen C, Mao Z * & Ge B*. (2018) Nuclear cGAS suppresses DNA repair and promotes tumorigenesis. Nature 563, 131–136. (Highlighted by Nature Reviews Molecular Cell Biology, Cancer Discovery and Science Signaling)
Zheng R#, Li Z#, He F#, Liu H*, Chen J, Cheng J, Xie X, Zhou J, Chen H, Wu X, Wu J, Chen B, Liu Y, Cui H, Fan L, Sha W, Liu Y, Wang J, Huang C, Zheng L, Xu F, Wang J,, Feng Y, Qin L, Yang H, Liu Z, Cui Z, Liu F, Chen X, Gao S, Sun S*, Shi Y* & Ge B*. (2018) Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese. Nature Communications 9, 4295.
Liu F#, Chen J#, Zhou Y, Liu H, Li H, Wang P, a Liu Z, Zheng R, Wang L, Yang H, Cui Z, Huang X, Wang J, Sha W, Xiao H & Ge B*. (2018) MicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagy. Nature Communications 9, 4072-
Zhou Y, He C, Yan D, Liu F, Liu H, Chen J, Cao T, Zuo M, Wang P, Ge Y, Lu H, Tong Q, Qin C, Deng Y, Ge B*. (2016) The kinase CK1ɛ controls the antiviral immune response by phosphorylating the signaling adaptor TRAF3. Nature Immunology 17(4):397-405.
Yan DP, Wang X., Li-Jun Luo LJ, Xuetao Cao X. and Ge B.* (2012) Inhibition of toll-like receptor signaling by an ITIM-containing bacterial protein. Nature Immunology, 13(11):1063-71
Kong L, Zhang H, Qin L, Zhuang ZH, Sun L, Yu MC, Zhu J, Chen Z. Wang ZG* and Ge B* 2009 An essential role for RIG-I in Toll-like receptor-mediated phagocytosis. Cell Host & Microbe 6(2):150-161. (Cited by “Faculty of 1000 Biology, Highlighted by Nature)
Yu MC, Su LL, Zou L, Liu Y, Wu N, Kong L, Zhuang ZH, Sun L, Liu HP, Hu JH, Li D, Strominger JL, Zang JW, Pei G*, Ge B.* (2008) An essential function for β-arrestin 2 in the inhibitory signaling of Natural Killer cells. Nature Immunology, 9(8):898-907. (Commented in Nature Immunology, Highlighted by Nature)
Kong L, Ge B*. (2008) MyD88-independent activation of a novel actin-Cdc42/Rac pathway is required for Toll-like receptor-stimulated phagocytosis. Cell Research. 18(7):745-55 (Cover Story)