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个人简介

魏振威,男,汉族,武汉大学化学与分子科学学院教授,分析科学研究中心主任。2007-2016年就读于清华大学化学系,分别获得化学学士与博士学位(导师张新荣教授)。2016-2020于美国普渡大学化学系Aston Lab从事博士后研究工作,合作导师R Graham Cooks教授。2021年加入武汉大学化学与分子科学学院工作,主要从事原位质谱分析方法学研究与仪器开发。在Chem,JACS,ACIE,Anal. Chem.等期刊上发表论文20余篇,参与编写质谱专著2部,获教育部自然科学奖一等奖一项(排名第六)。2021年入选国家海外高层次人才计划,武汉市“武汉英才”计划;主持国家自然科学基金2项,科技部重点项目(青年)1项。现担任中国化学快报(英文版)青年编委。 教育经历 2011.8 -- 2016.7 清华大学 化学 博士 2007.8 -- 2011.7 清华大学 化学 学士 工作经历 2016.10 -- 2020.10 普渡大学(Purdue University) 化学系 博士后研究员

研究领域

1.质谱离子化原理与质谱离子源 2.原位质谱反应监测方法 3. 超小体积生物质谱分析方法

近期论文

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Li, Y., Han, J., Wang, X., Wei, Z*., (2024) In-situ reaction monitoring and kinetics study of photochemical reactions by optical focusing inductive electrospray mass spectrometry. Chinese Chemical Letters, https://doi.org/10.1016/j.cclet.2024.110708 Cui, X., Chen, J., Yi, H., Wei, Z*., (2024), Mapping reaction pathways by in situ step sweep voltammetry flow electrochemical mass spectrometry. Analytical Chemistry, 96(44), 17765-17772. https://doi.org/10.1021/acs.analchem.4c04117 Liu, X., Chen, J., Wei, Z*., Yi, H.*, & Lei, A*. (2024). Deciphering reactive intermediates in electrooxidative coupling of indoles through real-time mass spectrometry. Chem, 10(7), 2131-2146. https://doi.org/10.1016/j.chempr.2024.02.020 Wang, W., Han, J., Zheng, Y., Wang, H., Zhu, C., Li, Y., Feng, Y., Wei, Z*. and Wang, X*. (2024). Direct Analysis of Whole Blood by a Disposable Monolithic Column Mass Spectrometry Analysis Kit. Chin. J. Chem. 42(10), 1073-1078. https://doi.org/10.1002/cjoc.202300646 Dong, J., Chen, J., Wang, W., Wei, Z*., Tian, Z. Q., & Fan, F. R*. (2024). Charged Microdroplets as Microelectrochemical Cells for CO2 Reduction and C–C Coupling. Journal of the American Chemical Society, 146(3), 2227-2236. https://doi.org/10.1021/jacs.3c12586 Xu, B., Li, Y., Wei, Z*., (2024).Familiarize students with direct MS analysis methods: localization of components in citrus peel by induced electrospray ionization. Journal of Chemical Education. 101(6), 2429–2435. https://doi.org/10.1021/acs.jchemed.4c00027 Han, J., Wang, X., Wang, W., Chen, J., Xu, B., & Wei, Z*. (2023). Direct Analysis of Micro-biopsy Samples by Polarity Gradient Focusing Dip-and-Go Mass Spectrometry. Analytical Chemistry, 95(35), 13266-13272. https://doi.org/10.1021/acs.analchem.3c02425 Chen, J., Wang, X., Cui, X., Li, Y., Feng, Y., & Wei, Z. (2023). In Situ Probing and Identification of Electrochemical Reaction Intermediates by Floating Electrolytic Electrospray Mass Spectrometry. Angewandte Chemie, 135(12), e202219302. https://doi.org/10.1002/ange.202219302 Wang, X., Bai, P., Li, Z., Zhu, Q. F., Wei, Z., & Feng, Y. Q. (2022). Rapid and economical chemoselective metabolomics using boronate ester formation on a monolithic substrate. Angewandte Chemie, 61(44), e202208138. https://doi.org/10.1002/anie.202208138 Chen, X., Wei, Z., Huang, K. H., Uehling, M., Wleklinski, M., Krska, S., ... & Cooks, R. G. (2022). Pd Reaction Intermediates in Suzuki‐Miyaura Cross‐Coupling Characterized by Mass Spectrometry. ChemPlusChem, 87(3), e202100545. https://doi.org/10.1002/cplu.202100545 Qiu, L., Wei, Z., Nie, H., & Cooks, R. G. (2021). Reaction acceleration promoted by partial solvation at the gas/solution interface. ChemPlusChem, 86(10), 1362-1365. https://doi.org/10.1002/cplu.202100373 Li, Y., Mehari, T. F., Wei, Z., Liu, Y., & Cooks, R. G. (2021). Reaction acceleration at air‐solution interfaces: Anisotropic rate constants for Katritzky transamination. Journal of Mass Spectrometry, 56(4), e4585. https://doi.org/10.1002/jms.4585 Li, Y., Mehari, T. F., Wei, Z., Liu, Y., & Cooks, R. G. (2021). Reaction acceleration at solid/solution interfaces: Katritzky reaction catalyzed by glass particles. Angewandte Chemie, 60(6), 2929-2933. https://doi.org/10.1002/anie.202014613 Huang, K. H., Wei, Z., & Cooks, R. G. (2021). Accelerated reactions of amines with carbon dioxide driven by superacid at the microdroplet interface. Chemical Science, 12(6), 2242-2250. https://doi.org/10.1039/D0SC05625A Chen, R., Wei, Z., & Cooks, R. G. (2020). Collection and Characterization by Mass Spectrometry of the Neutral Serine Octamer Generated upon Sublimation. Analytical Chemistry, 93(2), 1092-1099. https://doi.org/10.1021/acs.analchem.0c04107 Wei, Z., Li, Y., Cooks, R. G., & Yan, X. (2020). Accelerated reaction kinetics in microdroplets: Overview and recent developments. Annual Review of Physical Chemistry, 71, 31-51. https://doi.org/10.1146/annurev-physchem-121319-110654 Nie, H., Wei, Z., Qiu, L., Chen, X., Holden, D. T., & Cooks, R. G. (2020). High-yield gram-scale organic synthesis using accelerated microdroplet/thin film reactions with solvent recycling. Chemical Science, 11(9), 2356-2361. https://doi.org/10.1039/C9SC06265C Wei, Z., Xie, Z., Kuvelkar, R., Shah, V., Bateman, K., McLaren, D. G., & Cooks, R. G. (2019). High‐throughput bioassays using “dip‐and‐go” multiplexed electrospray mass spectrometry. Angewandte Chemie, 58(49), 17594-17598. https://doi.org/10.1002/anie.201909047 Fedick, P. W., Iyer, K., Wei, Z., Avramova, L., Capek, G. O., & Cooks, R. G. (2019). Screening of the suzuki cross-coupling reaction using desorption electrospray ionization in high-throughput and in leidenfrost droplet experiments. Journal of The American Society for Mass Spectrometry, 30(10), 2144-2151. https://doi.org/10.1007/s13361-019-02287-3 Zhang, H., Wei, Z., Jiang, J., & Cooks, R. G. (2018). Nebulization prior to isolation, ionization, and dissociation of the neutral serine octamer allows its characterization. Angewandte Chemie, 130(52), 17387-17391. https://doi.org/10.1002/ange.201811098 Wei, Z., Zhang, X., Wang, J., Zhang, S., Zhang, X., & Cooks, R. G. (2018). High yield accelerated reactions in nonvolatile microthin films: chemical derivatization for analysis of single-cell intracellular fluid. Chemical Science, 9(40), 7779-7786. https://doi.org/10.1039/C8SC03382J Wei, Z., Wleklinski, M., Ferreira, C., & Cooks, R. G. (2017). Reaction acceleration in thin films with continuous product deposition for organic synthesis. Angewandte Chemie, 129(32), 9514-9518. https://doi.org/10.1002/ange.201704520 Zhao, Y., Wei, Z., Zhao, H., Jia, J., Chen, Z., Zhang, S., ... & Zhang, X. (2016). In situ ion-transmission mass spectrometry for paper-based analytical devices. Analytical chemistry, 88(22), 10805-10810. https://doi.org/10.1021/acs.analchem.6b03272 Zhang, X. C., Wei, Z. W., Gong, X. Y., Si, X. Y., Zhao, Y. Y., Yang, C. D., ... & Zhang, X. R. (2016). Integrated droplet-based microextraction with ESI-MS for removal of matrix interference in single-cell analysis. Scientific reports, 6(1), 24730. https://doi.org/10.1038/srep24730 Wei, Z., Xiong, X., Guo, C., Si, X., Zhao, Y., He, M., ... & Zhang, X. (2015). Pulsed direct current electrospray: enabling systematic analysis of small volume sample by boosting sample economy. Analytical chemistry, 87(22), 11242-11248. https://doi.org/10.1021/acs.analchem.5b02115 Li, Y., Ma, X., Wei, Z., Gong, X., Yang, C., Zhang, S., & Zhang, X. (2015). Pyroelectricity Assisted Infrared-Laser Desorption Ionization (PAI-LDI) for Atmospheric Pressure Mass Spectrometry. Journal of The American Society for Mass Spectrometry, 26(8), 1266-1273. https://doi.org/10.1007/s13361-015-1154-6 Zhao, Y., Gong, X., Si, X., Wei, Z., Yang, C., Zhang, S., & Zhang, X. (2015). Coupling a solid phase microextraction (SPME) probe with ambient MS for rapid enrichment and detection of phosphopeptides in biological samples. Analyst, 140(8), 2599-2602. https://doi.org/10.1039/C4AN02156H Wei, Z., Han, S., Gong, X., Zhao, Y., Yang, C., Zhang, S., & Zhang, X. (2013). Rapid removal of matrices from small-volume samples by step-voltage nanoelectrospray. Angewandte Chemie, 52(42), 11025-11028. https://doi.org/10.1002/anie.201302870 Ma, X., Wei, Z., Xiong, X., Jiang, Y., He, J., Zhang, S., ... & Zhang, X. (2012). Gas-phase fragmentation of host–guest complexes between β-cyclodextrin and small molecules. Talanta, 93, 252-256. https://doi.org/10.1016/j.talanta.2012.02.029

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