个人简介
2017年博士毕业于北京大学，主要从事DNA损伤修复与肿瘤发生发展的相关研究，目前已在Science Advances、Nucleic Acids Res、Theranostics、Oncogene等发表论文，作为项目负责人主持国家自然科学基金面上项目1项，青年项目1项，上海市科委面上项目1项，并获得上海市“科技创新行动计划”启明星计划。
近期论文
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Tang Ming#*, Chen Guofang#, Tu Bo#, Hu Zhiyi, Huang Yujia, DuFort C. Christopher, Wan Xiaoping, Mao Zhiyong, Liu Yongzhong*, Zhu Wei-Guo*, Lu Wen*. SMYD2 inhibition mediated hypomethylation of Ku70 contributes to impaired non-homologous end joining repair and anti-tumor immunity, Science Advances, 2023, 9(24): eade6624.
Tang Ming#, Li Zhiming#, Zhang Chaohua, Lu Xiaopeng, Tu Bo, Cao Ziyang, Li Yinglu, Chen Yongcan, Jiang Lu, Wang Hui, Wang Lina, Wang Jiadong, Liu Baohua, Xu Xingzhi, Wang Haiying, Zhu Wei-Guo*, SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair, Science Advances, 2019, 5(3): eaav1118.
Tang Ming#, Lu Xiaopeng#, Zhang Chaohua, Du Changzheng, Cao Linlin, Hou Tianyun, Li Zhiming, Tu Bo, Cao Ziyang, Li Yinglu, Chen Yongcan, Jiang Lu, Wang Hui, Wang Lina, Liu Baohua, Xu Xingzhi, Luo Jianyuan, Wang Jiadong, Gu Jin, Wang Haiying*, Zhu Wei-Guo*, Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer, Theranostics, 2017, 7(5):1346-1359.
Lu Xiaopeng#, Tang Ming#, Zhu Qian, Yang Qiaoyan, Li Zhiming, Bao Yantao, Liu Ge, Hou Tianyun, Lv Yafei, Zhao Ying, Wang Haiying, Yang Yang, Cheng Zhongyi, Wen He, Liu Baohua, Xu Xingzhi, Gu Luo, Zhu Wei-Guo*, GLP-catalyzed H4K16me1 promotes 53BP1 recruitment to permit DNA damage repair and cell survival, Nucleic Acids Res, 2019,47(21):10977-10993.
Ma Aihui#, Tang Ming#, Zhang Li, Wang Boshi, Yang Zhaojuan, Liu Yun, Xu Guiqin, Wu Lin, Jing Tiantian, Xu Xiaoli, Yang Shengli, Liu Yongzhong*, USP1 inhibition destabilizes KPNA2 and suppresses breast cancer metastasis, Oncogene, 2018,38(13):2405-2419.
Tang Ming#, Tang Huangqi#, Tu Bo, Zhu Wei-Guo*, SIRT7: a sentinel of genome stability, Open Biology, 2021, 11(6):210047.
Zhai Zichao#, Tang Ming#, Yang Yue, Lu Ming, Zhu Wei-Guo*, Li Tingting*, Identifying Human SIRT1 Substrates by Integrating Heterogeneous Information from Various Sources, Sci Rep, 2017, 7(1):4614.
Tu Bo#, Bao Yantao#, Tang Ming#, Zhu Qian, Lu Xiaopeng, Wang Hui, Hou Tianyun, Zhao Ying, Zhang Ping*, Zhu Wei-Guo*, TIP60 recruits SUV39H1 to chromatin to maintain heterochromatin genome stability and resist hydrogen peroxide-induced cytotoxicity, Genome Instability & Disease, 2020, 1, 339-355.
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